Internalization and recycling of CD4 transfected into HeLa and NIH3T3 cells

scientific article published on December 1989

Internalization and recycling of CD4 transfected into HeLa and NIH3T3 cells is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID402046
P698PubMed publication ID2583114

P50authorMark MarshQ37383678
P2093author name stringPelchen-Matthews A
Armes JE
P2860cites workMolecular biology and function of CD4 and CD8Q24299317
Interaction between CD4 and class II MHC molecules mediates cell adhesionQ24339626
Receptor-mediated endocytosis: insights from the lipoprotein receptor systemQ24596157
The CD4 receptor is complexed in detergent lysates to a protein-tyrosine kinase (pp58) from human T lymphocytesQ24653345
Membrane flow during pinocytosis. A stereologic analysisQ24682143
Measurement of protein using bicinchoninic acidQ26778491
Human immunodeficiency virus infection of T cells and monocytes proceeds via receptor-mediated endocytosisQ27482398
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirusQ28259668
Lymphocyte activation by HIV-1 envelope glycoproteinQ28281341
The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lckQ28506433
Signal transduction through the CD4 receptor involves the activation of the internal membrane tyrosine-protein kinase p56lckQ28511623
Binding of the human retrovirus HTLV-III/LAV/ARV/HIV to the CD4 (T4) molecule: conformation dependence, epitope mapping, antibody inhibition, and potential for idiotypic mimicryQ28646789
Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptorQ28646793
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAVQ28646817
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brainQ29618472
Transferrin receptor and its recycling in HeLa cellsQ33927904
Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigenQ34685578
Surface distribution and recycling of the low density lipoprotein receptor as visualized with antireceptor antibodiesQ36206225
Perturbation of the T4 molecule transmits a negative signal to T cellsQ36350963
Transport of macrophage Fc receptors and Fc receptor-bound ligands to lysosomesQ36351748
Variable and conserved neutralization antigens of human immunodeficiency virusQ38891686
Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanismQ41091293
Evidence that pinocytosis in lymphoid cells has a low capacityQ41502421
Antibody to mannose 6-phosphate specific receptor induces receptor deficiency in human fibroblastsQ41573025
pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membraneQ41764642
Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: effect of HIV sequence variation and a mechanism for CD4+ cell depletionQ42818707
Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4.Q44534068
The role of the L3T4 molecule in mitogen and antigen-activated signal transductionQ44807312
Role of the L3T4-antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cellsQ44844175
Human immunodeficiency virus infection of monocytic and T-lymphocytic cells: receptor modulation and differentiation induced by phorbol esterQ44890078
HIV infection does not require endocytosis of its receptor, CD4.Q45149382
Adsorptive endocytosis of Semliki Forest virusQ45790815
The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene familyQ48376775
Phosphorylation of CD4 and CD8 molecules following T cell triggering.Q50899650
T4 endocytosis and phosphorylation induced by phorbol esters but not by mitogen or HIV infection.Q54389507
Transient modulation and internalization of T4 antigen induced by phorbol esters.Q54424003
T cells can present antigens such as HIV gp120 targeted to their own surface moleculesQ57160468
Evidence for a physical association of CD4 and the CD3: α : β T-cell receptorQ58974599
Expression and function of CD4 in a murine T-cell hybridomaQ58974630
Distribution of the transferrin receptor in normal human fibroblasts and fibrosarcoma cellsQ67276205
Stimulation and proliferation of CD4+ peripheral blood T lymphocytes induced by an anti-CD4 monoclonal antibodyQ68092456
The role of L3T4 in T cell activation: L3T4 may be both an Ia-binding protein and a receptor that transduces a negative signalQ68856856
Recognition of HIV glycoprotein gp120 by T cells. Role of monocyte CD4 in the presentation of gp120Q69330430
Requirements for modulation of the CD4 molecule in response to phorbol myristate acetate. Role of the cytoplasmic domainQ69735860
Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigenQ70017245
CD4 molecules are associated with the antigen receptor complex on activated but not resting T cellsQ70052178
Modulation of CD4 by antigenic activationQ70322737
Lymphokine activation of T4+ T lymphocytes and monocytesQ70341772
Preparation of F(ab')2 fragments from mouse IgG of various subclassesQ70426518
Kinetics of internalization and recycling of the asialoglycoprotein receptor in a hepatoma cell lineQ72926638
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)3641-3649
P577publication date1989-12-01
P1433published inThe EMBO JournalQ1278554
P1476titleInternalization and recycling of CD4 transfected into HeLa and NIH3T3 cells
P478volume8

Reverse relations

cites work (P2860)
Q37697278A novel endocytosis signal related to the KKXX ER-retrieval signal
Q33820909An acidic cluster in the cytosolic domain of human cytomegalovirus glycoprotein B is a signal for endocytosis from the plasma membrane
Q36236526An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface
Q36957794CCL2 increases X4-tropic HIV-1 entry into resting CD4+ T cells.
Q36793470CD4 is retained in the endoplasmic reticulum by the human immunodeficiency virus type 1 glycoprotein precursor
Q39550956CD4-Chemokine receptor hybrids in human immunodeficiency virus type 1 infection.
Q36845470Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation
Q41834240Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells
Q33888654Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site
Q41518173Endocytosis of glycophospholipid-anchored and transmembrane forms of CD4 by different endocytic pathways
Q36764375Genetic analysis of the variable region genes encoding a monospecific human natural anti-DNA antibody
Q33581852HIV-1 clade B Tat, but not clade C Tat, increases X4 HIV-1 entry into resting but not activated CD4+ T cells
Q40067319Human immunodeficiency virus type 1 NL4-3 replication in four T-cell lines: rate and efficiency of entry, a major determinant of permissiveness
Q39868503Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes
Q36625495Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4.
Q36499676Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways
Q36158056Identification and characterization of two CD4 alleles in Microminipigs
Q24533226Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes
Q34333514Mutation of the dominant endocytosis motif in human immunodeficiency virus type 1 gp41 can complement matrix mutations without increasing Env incorporation
Q30175880Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking
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Q24678715Nef-mediated clathrin-coated pit formation
Q42805965Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting
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Q41632663The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits

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