review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0065-230X(08)60958-6 |
P698 | PubMed publication ID | 8394044 |
P2093 | author name string | Fujiki H | |
Suganuma M | |||
P2860 | cites work | jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun | Q24302170 |
Molecular cloning and expression of a receptor for human tumor necrosis factor | Q24303604 | ||
Association of protein phosphatase 2A with polyoma virus medium tumor antigen | Q24558730 | ||
Dephosphorylation of simian virus 40 large-T antigen and p53 protein by protein phosphatase 2A: inhibition by small-t antigen | Q24603984 | ||
Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes | Q28277749 | ||
Ca2(+)-calmodulin-dependent protein kinase II phosphorylates various types of non-epithelial intermediate filament proteins | Q28300112 | ||
Liver tumor promotion by the cyanobacterial cyclic peptide toxin microcystin-LR | Q28320616 | ||
ras genes | Q29547799 | ||
The role of protein kinase C in cell surface signal transduction and tumour promotion | Q29618532 | ||
The structure and regulation of protein phosphatases | Q29618929 | ||
Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism | Q29619866 | ||
Structural characterization of toxic cyclic peptides from blue-green algae by tandem mass spectrometry | Q30450854 | ||
Okadaic acid: an additional non-phorbol-12-tetradecanoate-13-acetate-type tumor promoter | Q33559371 | ||
Molecular cloning and expression of the human 55 kd tumor necrosis factor receptor | Q33903826 | ||
Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis | Q34162269 | ||
Polyoma small and middle T antigens and SV40 small t antigen form stable complexes with protein phosphatase 2A. | Q34181194 | ||
Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants | Q34188529 | ||
Indole alkaloids: dihydroteleocidin B, teleocidin, and lyngbyatoxin A as members of a new class of tumor promoters | Q34269711 | ||
Okadaic acid and dinophysistoxin-1, non-TPA-type tumor promoters, stimulate prostaglandin E2 production in rat peritoneal macrophages | Q69234415 | ||
Codon 61 mutations in the c-Harvey-ras gene in mouse skin tumors induced by 7,12-dimethylbenz[a]anthracene plus okadaic acid class tumor promoters | Q69241108 | ||
Okadaic acid, a specific protein phosphatase inhibitor, induces maturation and MPF formation in Xenopus laevis oocytes | Q69334325 | ||
Calyculin A and okadaic acid: inhibitors of protein phosphatase activity | Q69337324 | ||
Effects of okadaic acid on mouse hemopoietic cells | Q69392036 | ||
Preparation of monoclonal antibodies against okadaic acid prepared from the sponge Halichondria okadai | Q69454381 | ||
Vimentin, a cytoskeletal substrate of protein kinase C | Q69818641 | ||
Effect of okadaic acid on phosphorylation-dephosphorylation of myosin light chain in aortic smooth muscle homogenate | Q69828701 | ||
Tumor promoting activity of teleocidin in skin and forestomach of mice initiated transplacentally with 7,12-dimethylbenz(a)anthracene | Q70332263 | ||
Diaplacental initiation of NMRI mice with 7,12-dimethylbenz[a]anthracene during gestation days 6--20 and postnatal treatment of the F1-generation with the phorbol ester 12-O-tetradecanoylphorbol-13-acetate: tumor incidence in organs other than the s | Q71581300 | ||
Phosphorylation of intermediate filament proteins by cAMP-dependent protein kinases | Q72886404 | ||
Nodularin, microcystin, and the configuration of Adda | Q78319628 | ||
Identification of 12 hepatotoxins from a Homer Lake bloom of the cyanobacteria Microcystis aeruginosa, Microcystis viridis, and Microcystis wesenbergii: nine new microcystins | Q78328681 | ||
The structure of cyanoginosin-LA, a cyclic heptapeptide toxin from the cyanobacterium Microcystis aeruginosa | Q104246623 | ||
Evidence of liver damage by toxin from a bloom of the blue‐green alga, Microcystis aeruginosa | Q104391898 | ||
Calyculins E, F, G, and H, additional inhibitors of protein phosphatases 1 and 2a, from the marine sponge discodermia calyx | Q104397534 | ||
Bioactive marine metabolites. Part 16. Calyculin A. A novel antitumor metabolite from the marine sponge Discodermia calyx | Q104996461 | ||
Acanthifolicin, a new episulfide-containing polyether carboxylic acid from extracts of the marine sponge Pandaros acanthifolium | Q105205556 | ||
Flat reversion by okadaic acid of raf and ret-II transformants | Q34325946 | ||
Tumor necrosis factor (TNF). | Q34378376 | ||
Allelotype of colorectal carcinomas | Q34461209 | ||
Structure-Function Relationships of Microcystins, Liver Tumor Promoters, in Interaction with Protein Phosphatase | Q34507668 | ||
Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases | Q34631024 | ||
Toxins contained in Microcystis species of cyanobacteria (blue-green algae). | Q34686085 | ||
Mechanisms of action of okadaic acid class tumor promoters on mouse skin | Q35034113 | ||
Is the inhibition of protein phosphatase 1 and 2A activities a general mechanism of tumor promotion in human cancer development? | Q35226651 | ||
Toxicity and partial structure of a hepatotoxic peptide produced by the cyanobacterium Nodularia spumigena Mertens emend. L575 from New Zealand | Q36071590 | ||
Dual regulation of intermediate filament phosphorylation | Q36210185 | ||
Modulation of fibroblast functions by interleukin 1: increased steady-state accumulation of type I procollagen messenger RNAs and stimulation of other functions but not chemotaxis by human recombinant interleukin 1 alpha and beta | Q36218317 | ||
When worlds collide: immunosuppressants meet protein phosphatases | Q36680216 | ||
Regulation of collagenase gene expression by okadaic acid, an inhibitor of protein phosphatases | Q36735394 | ||
Cytoskeletal integrity in interphase cells requires protein phosphatase activity | Q37308359 | ||
Protein phosphatase inhibitor okadaic acid enhances transmitter release at neuromuscular junctions | Q37417185 | ||
Specific labeling of mouse brain membrane phospholipids with [20-3H]phorbol 12-p-azidobenzoate 13-benzoate, a photolabile phorbol ester | Q37612325 | ||
Regulation of gene expression by tumor promoters | Q38038962 | ||
Tumor necrosis, cachexia, shock, and inflammation: a common mediator | Q39532135 | ||
Molecular and cellular biology of intermediate filaments | Q39532153 | ||
The protein phosphatase inhibitor okadaic acid induces morphological changes typical of apoptosis in mammalian cells | Q41129663 | ||
Okadaic acid induces the expression of both early and secondary response genes in mouse keratinocytes | Q41646684 | ||
Rapid histone H3 phosphorylation in response to growth factors, phorbol esters, okadaic acid, and protein synthesis inhibitors | Q41683430 | ||
Phosphorylation of nuclear protein is an early event in TGFβ1 action | Q41690730 | ||
Regulation of progesterone receptor-mediated transcription by phosphorylation | Q41710148 | ||
Intermediate filament reorganization during mitosis is mediated by p34cdc2 phosphorylation of vimentin | Q41721264 | ||
Hepatocellular uptake of 3H-dihydromicrocystin-LR, a cyclic peptide toxin | Q41731167 | ||
The non-phorbol ester tumor promoter okadaic acid does not promote morphological transformation or inhibit junctional communication in hamster embryo cells | Q41739960 | ||
Cell cycle oscillation of phosphatase inhibitor-2 in rat fibroblasts coincident with p34cdc2 restriction | Q41740976 | ||
Computer modelling of the 3-dimensional structures of the cyanobacterial hepatotoxins microcystin-LR and nodularin | Q41837487 | ||
Promotion of BALB/3T3 cell transformation by the okadaic acid class of tumor promoters, okadaic acid and dinophysistoxin-1. | Q41867607 | ||
Inhibition of protein phosphatases by microcystins and nodularin associated with hepatotoxicity | Q41901692 | ||
Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A | Q41973818 | ||
Specific binding of okadaic acid, a new tumor promoter in mouse skin | Q42057482 | ||
Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics | Q42163759 | ||
Phospholipids involved in specific binding of 12-O-(5-azido-2-nitrobenzoyl)phorbol-13-acetate to epidermal microsomes, a photolabeling study | Q42224354 | ||
The tumor promoters 12-O-tetradecanoylphorbol-13-acetate and okadaic acid differ in toxicity, mitogenic activity and induction of gene expression | Q42796260 | ||
Mouse skin carcinomas induced in vivo by chemical carcinogens have a transforming Harvey-ras oncogene | Q42823403 | ||
Calyculin-A increases the level of protein phosphorylation and changes the shape of 3T3 fibroblasts | Q42829835 | ||
Okadaic acid and phorbol esters: comparative effects of these tumor promoters on cell transformation, intercellular communication and differentiation in vitro | Q42832457 | ||
Okadaic acid identifies a phosphorylation/dephosphorylation cycle controlling the inhibitory guanine-nucleotide-binding regulatory protein Gi2 | Q42860144 | ||
Characterization of chemically tritiated microcystin-LR and its distribution in mice | Q43687348 | ||
The role of the kappa enhancer and its binding factor NF-kappa B in the developmental regulation of kappa gene transcription | Q43814141 | ||
Activity of diverse tumor promoters in a keratinocyte co-culture model of initiated epidermis | Q44242337 | ||
Binding competition of okadaic acid derivatives to anti-okadaic acid antibody | Q44404670 | ||
Apparent "activation" of protein kinases by okadaic acid class tumor promoters | Q44550752 | ||
Photoaffinity labeling of protein phosphatase 2A, the receptor for a tumor promoter okadaic acid, by [27-3H]methyl 7-O-(4-azidobenzoyl)okadaate | Q44796766 | ||
Vimentin is hyperphosphorylated in primary human fibroblasts treated with okadaic acid | Q45035649 | ||
Smooth muscle myosin phosphatase inhibition and force enhancement by black sponge toxin | Q46175060 | ||
Effects of a protein phosphatase inhibitor, okadaic acid, on membrane currents of isolated guinea-pig cardiac myocytes | Q46473208 | ||
Rapid purification of protein phosphatase 2A from mouse brain by microcystin-affinity chromatography | Q48795241 | ||
The marine toxin okadaic acid is a potent neurotoxin for cultured cerebellar neurons | Q48830106 | ||
Structure-activity relationship within a series of okadaic acid derivatives | Q48890052 | ||
Structurally different members of the okadaic acid class selectively inhibit protein serine/threonine but not tyrosine phosphatase activity | Q50791473 | ||
Isolation and characterization of the minor components associated with microcystins LR and RR in the cyanobacterium (blue-green algae). | Q50883683 | ||
Naming of cyclic heptapeptide toxins of cyanobacteria (blue-green algae). | Q50899038 | ||
Permeability of a non-TPA-type tumor promoter, okadaic acid, through lipid bilayer membrane. | Q53506577 | ||
Diarrhetic shellfish toxin, dinophysistoxin-1, is a potent tumor promoter on mouse skin. | Q53520166 | ||
Teleocidin from Streptomyces is a potent promoter of mouse skin carcinogenesis. | Q53567537 | ||
A novel protein phosphatase inhibitor, tautomycin. Effect on smooth muscle. | Q53858292 | ||
Okadaic acid is a potent angiogenesis inducer | Q55260182 | ||
Poisonous Australian Lake | Q56455113 | ||
Diarrhetic shellfish toxins | Q57310225 | ||
Okadaic acid, a cytotoxic polyether from two marine sponges of the genus Halichondria | Q57310226 | ||
Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism | Q59067763 | ||
Tautomycin from the bacterium Streptomyces verticillatus | Q61770148 | ||
Bioactive marine metabolites. 24. Isolation and structure elucidation of calyculins B, C, and D, novel antitumor metabolites, from the marine sponge Discodermia calyx | Q61861448 | ||
Induction of ornithine decarboxylase activity in mouse skin by a possible tumor promoter, okadaic acid | Q62661150 | ||
Analysis and purification of toxic peptides from cyanobacteria by reversed-phase high-performance liquid chromatography | Q67237532 | ||
Hyperphosphorylation of cytokeratins 8 and 18 by microcystin-LR, a new liver tumor promoter, in primary cultured rat hepatocytes | Q67466257 | ||
An alternative theory of tissue specificity by tumor promotion of okadaic acid in glandular stomach of SD rats | Q67505739 | ||
Induction of morphological change of human myeloid leukemia and activation of protein kinase C by a novel antibiotic, tautomycin | Q67925484 | ||
Production of antibodies and development of a radioimmunoassay for okadaic acid | Q68103977 | ||
Increased activity of the eEF-2 specific, Ca2+ and calmodulin dependent protein kinase III during the S-phase in Ehrlich ascites cells | Q68263610 | ||
Structural determination of geometrical isomers of microcystins LR and RR from cyanobacteria by two-dimensional NMR spectroscopic techniques | Q68397042 | ||
How does interleukin 1 activate cells? Interleukin 1 signal transduction | Q68440903 | ||
In vitro and in vivo effects of protein phosphatase inhibitors, microcystins and nodularin, on mouse skin and fibroblasts | Q68478485 | ||
Histopathological studies on experimental marine toxin poisoning. I. Ultrastructural changes in the small intestine and liver of suckling mice induced by dinophysistoxin-1 and pectenotoxin-1 | Q68976935 | ||
A new antibiotic, tautomycin | Q69138351 | ||
P407 | language of work or name | English | Q1860 |
P921 | main subject | Tumor promotion | Q7852681 |
P304 | page(s) | 143-194 | |
P577 | publication date | 1993-01-01 | |
P1433 | published in | Advances in Cancer Research | Q3113522 |
P1476 | title | Tumor promotion by inhibitors of protein phosphatases 1 and 2A: the okadaic acid class of compounds | |
P478 | volume | 61 |
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Q33510686 | ADP ribosylation factor like 2 (Arl2) regulates breast tumor aggressivity in immunodeficient mice |
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Q48422366 | Acute or chronic administration of okadaic acid to rats induces brain damage rather than Alzheimer-like neuropathology |
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Q28690003 | Biological importance of marine algae |
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Q59265479 | Chapter 1 Recent Developments in Mediterranean Harmful Algal Events |
Q38357113 | Characterization of a unique aspartate-rich protein of the SET/TAF-family in the human malaria parasite, Plasmodium falciparum, which inhibits protein phosphatase 2A. |
Q38828243 | Combination of zoledronic acid and serine/threonine phosphatase inhibitors induces synergistic cytotoxicity and apoptosis in human breast cancer cells via inhibition of PI3K/Akt pathway. |
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