Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells

scientific article

Transforming properties of chimeric TEL-JAK proteins in Ba/F3 cells is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID10706877

P2093author name stringBernard OA
Berger R
Ghysdael J
Gisselbrecht S
Gouilleux F
Mayeux P
Mauchauffé M
Boureux A
Lacronique V
Dumon S
Monni R
P433issue6
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)2076-2083
P577publication date2000-03-01
P1433published inBloodQ885070
P1476titleTransforming properties of chimeric TEL-JAK proteins in Ba/F3 cells
P478volume95

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cites work (P2860)
Q245482508p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways
Q40434680Activated STAT5 proteins induce activation of the PI 3-kinase/Akt and Ras/MAPK pathways via the Gab2 scaffolding adapter
Q36936510Alternative TEL-JAK2 fusions associated with T-cell acute lymphoblastic leukemia and atypical chronic myelogenous leukemia dissected in zebrafish
Q38712212Anti-leukaemic activity of the TYK2 selective inhibitor NDI-031301 in T-cell acute lymphoblastic leukaemia.
Q39128976Canonical and Non-Canonical Aspects of JAK-STAT Signaling: Lessons from Interferons for Cytokine Responses
Q47422245Cucurbitacin I inhibits STAT3, but enhances STAT1 signaling in human cancer cells in vitro through disrupting actin filaments
Q38763094Development of Selective Covalent Janus Kinase 3 Inhibitors.
Q40288223Discovery and characterization of LY2784544, a small-molecule tyrosine kinase inhibitor of JAK2V617F.
Q60923199Ex Vivo Transposon-Mediated Genetic Screens for Cancer Gene Discovery
Q35120026Expression of TEL-JAK2 in primary human hematopoietic cells drives erythropoietin-independent erythropoiesis and induces myelofibrosis in vivo
Q37316601Following the cytokine signaling pathway to leukemogenesis: a chronology
Q33611301Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53
Q36740156In vivo identification of novel STAT5 target genes
Q27004027Inhibition of STAT5: a therapeutic option in BCR-ABL1-driven leukemia
Q26782539JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications
Q33586552Jak2 inhibitors: rationale and role as therapeutic agents in hematologic malignancies
Q34071332Jaks and stats as therapeutic targets
Q26991810Janus kinase deregulation in leukemia and lymphoma
Q24322021Janus kinases in immune cell signaling
Q35879915Kinome-wide selectivity profiling of ATP-competitive mammalian target of rapamycin (mTOR) inhibitors and characterization of their binding kinetics
Q41528529Modeling ETV6-JAK2-induced leukemia: insights from the zebrafish
Q42433996Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade
Q92814428Pharmacological Inhibition of Oncogenic STAT3 and STAT5 Signaling in Hematopoietic Cancers
Q27633822Polymerization of the SAM domain of TEL in leukemogenesis and transcriptional repression
Q37291219Posttranslational modification of TEL and TEL/AML1 by SUMO-1 and cell-cycle-dependent assembly into nuclear bodies
Q38116768STAT transcription factors in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention
Q33559005Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation
Q34627064Stat proteins and oncogenesis
Q42657514Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl+ K562 and Jak2(V617F)+ HEL Leukemia Cells.
Q35822851Suppression of cytokine signaling by SOCS3: characterization of the mode of inhibition and the basis of its specificity
Q36836799TYK2-STAT1-BCL2 pathway dependence in T-cell acute lymphoblastic leukemia
Q37347522Targeting signal transducer and activator of transcription signaling pathway in leukemias.
Q33613105The JAK2 inhibitor AZD1480 potently blocks Stat3 signaling and oncogenesis in solid tumors
Q38349780The influence of STAT5 antisense oligonucleotides on the proliferation and apoptosis of selected human leukaemic cell lines
Q24308570The tumor suppressor hTid1 inhibits STAT5b activity via functional interaction
Q24658483Therapeutic targeting of Janus kinases
Q34182738Transforming and tumorigenic activity of JAK2 by fusion to BCR: molecular mechanisms of action of a novel BCR-JAK2 tyrosine-kinase
Q37919976Tyrosine kinase gene fusions in cancer: translating mechanisms into targeted therapies
Q28081638Zebrafish as a model for leukemia and other hematopoietic disorders
Q34570939t(8;9)(p22;p24)/PCM1-JAK2 activates SOCS2 and SOCS3 via STAT5.