Regulation of c-myc transcription by interleukin-2 (IL-2). Identification of a novel IL-2 response element interacting with STAT-4.

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Regulation of c-myc transcription by interleukin-2 (IL-2). Identification of a novel IL-2 response element interacting with STAT-4. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.275.10.7343
P698PubMed publication ID10702306

P2093author name stringGrigoriev VG
Hoover RG
Grigorieva I
Rowney MK
P2860cites workInterleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12Q24306559
Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferationQ24316156
STAM, signal transducing adaptor molecule, is associated with Janus kinases and involved in signaling for cell growth and c-myc inductionQ28236871
Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunitsQ28241606
Stat4, a novel gamma interferon activation site-binding protein expressed in early myeloid differentiationQ28243701
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cellsQ28244421
An interleukin-4-induced transcription factor: IL-4 StatQ28248059
A non-AUG translational initiation in c-myc exon 1 generates an N-terminally distinct protein whose synthesis is disrupted in Burkitt's lymphomasQ28294528
Interleukin 12 induces tyrosine phosphorylation and activation of STAT4 in human lymphocytesQ28295404
Protein tyrosine kinase Syk is associated with and activated by the IL-2 receptor: possible link with the c-myc induction pathwayQ28610817
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6Q28637521
STATs and Gene RegulationQ29547796
Interleukin-12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunityQ29619700
E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factorQ33856709
Critical role of the interleukin 2 (IL-2) receptor gamma-chain-associated Jak3 in the IL-2-induced c-fos and c-myc, but not bcl-2, gene inductionQ33921686
Approaches to DNA Mutagenesis: An OverviewQ34451063
Deregulated messenger RNA expression during T cell apoptosisQ34782647
DNA topology of the ordered chromatin domain 5' to the human c-myc geneQ35222859
myc function and regulationQ35671084
Induction of interferon gamma production by natural killer cell stimulatory factor: characterization of the responder cells and synergy with other inducersQ36361001
Interleukin 12 signaling in T helper type 1 (Th1) cells involves tyrosine phosphorylation of signal transducer and activator of transcription (Stat)3 and Stat4Q36364774
A nuclease-hypersensitive element of the human c-myc promoter interacts with a transcription initiation factor.Q36796109
Transcriptional repression of the E2-containing promoters EIIaE, c-myc, and RB1 by the product of the RB1 geneQ36821079
Novel promoter upstream of the human c-myc gene and regulation of c-myc expression in B-cell lymphomasQ36897540
Binding in vitro of multiple cellular proteins to immunoglobulin heavy-chain enhancer DNA.Q36901029
Differential promoter utilization by the c-myc gene in mitogen- and interleukin-2-stimulated human lymphocytesQ36920022
Regulation of c-myc mRNA levels in normal human lymphocytes by modulators of cell proliferationQ37692274
Nuclear factor E2F mediates basic transcription and trans-activation by E1a of the human MYC promoterQ38344934
Myc and Max proteins possess distinct transcriptional activitiesQ39499398
Identification of two enhancer elements downstream of the human c-myc geneQ40392540
The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transductionQ40661162
The Jak-STAT pathway: specific signal transduction from the cell membrane to the nucleusQ41017022
IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signaling pathways: demonstration of a novel role for c-mycQ41614199
A restricted cytoplasmic region of IL-2 receptor beta chain is essential for growth signal transduction but not for ligand binding and internalizationQ41759523
Consequences of widespread deregulation of the c-myc gene in transgenic mice: multiple neoplasms and normal developmentQ43512505
Posttranscriptional mechanisms are responsible for accumulation of truncated c-myc RNAs in murine plasma cell tumorsQ45084498
A FOS protein is present in a complex that binds a negative regulator of MYC.Q46185313
Chromatin structure and protein binding in the putative regulatory region of the c-myc gene in Burkitt lymphoma.Q48390236
The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic miceQ57338722
A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cellsQ59074575
Sequence requirements for premature termination of transcription in the human c-myc geneQ69824205
Differential expression of the translocated and the untranslocated c-myc oncogene in Burkitt lymphomaQ70449918
Analysis of human breast cancer nuclear proteins binding to the promoter elements of the c-myc geneQ71259707
Novel DNase I hypersensitive sites in the 3'-flanking region of the human c-myc geneQ71394502
Cooperation of natural killer cell stimulatory factor/interleukin-12 with other stimuli in the induction of cytokines and cytotoxic cell-associated molecules in human T and NK cellsQ72684162
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)7343-7350
P577publication date2000-03-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleRegulation of c-myc transcription by interleukin-2 (IL-2). Identification of a novel IL-2 response element interacting with STAT-4.
P478volume275

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cites work (P2860)
Q44717067Alterations of oncogenes expression in NK cells in patients with cancer
Q52593708EBNA1: Oncogenic Activity, Immune Evasion and Biochemical Functions Provide Targets for Novel Therapeutic Strategies against Epstein-Barr Virus- Associated Cancers
Q34986687Growth suppression by acute promyelocytic leukemia-associated protein PLZF is mediated by repression of c-myc expression
Q36370831Regulating type 1 IFN effects in CD8 T cells during viral infections: changing STAT4 and STAT1 expression for function
Q35988744Signal transducer and activator of transcription STAT5 is recruited to c-Myc super-enhancer
Q37013896The c-myc promoter: still MysterY and challenge

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