Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot.

scientific article

Identification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/CMDC.201500454
P698PubMed publication ID26553423

P50authorXiao YuQ56936950
Hao FangQ56972680
P2093author name stringPeng Xiao
Xu Chen
Lin Ge
Dao-lai Zhang
Hong-da Liu
Xu-Ben Hou
Jin-peng Sun
Dong-fang He
Du-xiao Yang
Kang-shuai Li
Ke-rui Han
Xiao-yuan Song
P2860cites workLIM kinase and slingshot are critical for neurite extensionQ79951658
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Fast identification of novel lymphoid tyrosine phosphatase inhibitors using target-ligand interaction-based virtual screeningQ85913041
Cofilin-phosphatase slingshot-1L (SSH1L) is over-expressed in pancreatic cancer (PC) and contributes to tumor cell migrationQ86743332
Control of actin reorganization by Slingshot, a family of phosphatases that dephosphorylate ADF/cofilinQ24292264
A pathway of neuregulin-induced activation of cofilin-phosphatase Slingshot and cofilin in lamellipodiaQ24294191
Protein kinase D1 regulates cofilin-mediated F-actin reorganization and cell motility through slingshotQ24310778
Interplay between components of a novel LIM kinase-slingshot phosphatase complex regulates cofilinQ24338579
The catalytic role of the M2 metal ion in PP2CαQ27698056
The catalytic region and PEST domain of PTPN18 distinctly regulate the HER2 phosphorylation and ubiquitination barcodesQ28118816
Mosaic PPM1D mutations are associated with predisposition to breast and ovarian cancerQ28388006
The cofilin phosphatase slingshot homolog 1 (SSH1) links NOD1 signaling to actin remodelingQ28542810
Suppression of the invasive capacity of rat ascites hepatoma cells by knockdown of Slingshot or LIM kinaseQ28580489
GPCR-mediated PLCβγ/PKCβ/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis.Q30621940
Targeting the disordered C terminus of PTP1B with an allosteric inhibitorQ33774262
Exome sequencing identifies somatic gain-of-function PPM1D mutations in brainstem gliomasQ33813999
Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).Q34093722
Control of growth cone motility and morphology by LIM kinase and Slingshot via phosphorylation and dephosphorylation of cofilin.Q34189411
Efficient Salmonella entry requires activity cycles of host ADF and cofilinQ34310027
Cofilin phosphatases and regulation of actin dynamicsQ36336031
The WIP1 oncogene promotes progression and invasion of aggressive medulloblastoma variantsQ36490004
Cadmium is a potent inhibitor of PPM phosphatases and targets the M1 binding siteQ37061354
Molecular mechanism of ERK dephosphorylation by striatal-enriched protein tyrosine phosphataseQ37626207
Signaling mechanisms and functional roles of cofilin phosphorylation and dephosphorylationQ38059941
Wip1 phosphatase in breast cancerQ38266298
Allosteric Wip1 phosphatase inhibition through flap-subdomain interaction.Q39037345
Formation of cofilin-actin rods following cucurbitacin-B-induced actin aggregation depends on Slingshot homolog 1-mediated cofilin hyperactivation.Q39148929
Rho GTPases regulate axon growth through convergent and divergent signaling pathways.Q47071970
Inactivation of brain Cofilin-1 by age, Alzheimer's disease and γ-secretaseQ48485476
The role of the MKK6/p38 MAPK pathway in Wip1-dependent regulation of ErbB2-driven mammary gland tumorigenesis.Q53595739
P433issue12
P304page(s)1980-1987
P577publication date2015-11-10
P1433published inChemMedChemQ2962252
P1476titleIdentification of para-Substituted Benzoic Acid Derivatives as Potent Inhibitors of the Protein Phosphatase Slingshot
P478volume10

Reverse relations

Q41660620Critical Roles of Dual-Specificity Phosphatases in Neuronal Proteostasis and Neurological Diseases.cites workP2860

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