scholarly article | Q13442814 |
P50 | author | Andreas Aufschnaiter | Q40999037 |
Tobias Eisenberg | Q56418521 | ||
Sabrina Büttner | Q59661707 | ||
Verena Kohler | Q87983331 | ||
Walter Keller | Q38325496 | ||
P2093 | author name string | Didac Carmona-Gutierrez | |
Lukas Habernig | |||
Jutta Diessl | |||
P2860 | cites work | Alpha-synuclein promotes SNARE-complex assembly in vivo and in vitro | Q24629968 |
A mutation in VPS35, encoding a subunit of the retromer complex, causes late-onset Parkinson disease | Q24633417 | ||
Distinct domains within Vps35p mediate the retrieval of two different cargo proteins from the yeast prevacuolar/endosomal compartment | Q24657977 | ||
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models | Q24683059 | ||
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Q25938999 | ||
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease | Q27860459 | ||
alpha-Synuclein locus triplication causes Parkinson's disease | Q27860533 | ||
α-Synuclein in Lewy bodies | Q27860680 | ||
Fiji: an open-source platform for biological-image analysis | Q27860912 | ||
A yeast homolog of the mammalian mannose 6-phosphate receptors contributes to the sorting of vacuolar hydrolases. | Q27932012 | ||
Multiple pathways for vacuolar sorting of yeast proteinase A. | Q27935051 | ||
Vps10p cycles between the late-Golgi and prevacuolar compartments in its function as the sorting receptor for multiple yeast vacuolar hydrolases. | Q27938475 | ||
Cytosolic Ca2+ homeostasis is a constitutive function of the V-ATPase in Saccharomyces cerevisiae | Q27938711 | ||
The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene | Q27939402 | ||
Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products | Q27939459 | ||
Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting | Q27939994 | ||
A versatile toolbox for PCR-based tagging of yeast genes: new fluorescent proteins, more markers and promoter substitution cassettes | Q28131622 | ||
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders | Q28205399 | ||
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease | Q28300290 | ||
Transformation of yeast by lithium acetate/single-stranded carrier DNA/polyethylene glycol method | Q29547550 | ||
Critical role of calpain-mediated cleavage of calcineurin in excitotoxic neurodegeneration. | Q33195171 | ||
Cathepsin D is the main lysosomal enzyme involved in the degradation of alpha-synuclein and generation of its carboxy-terminally truncated species | Q33360061 | ||
VPS35, the Retromer Complex and Parkinson's Disease. | Q33708940 | ||
Alpha-synuclein delays endoplasmic reticulum (ER)-to-Golgi transport in mammalian cells by antagonizing ER/Golgi SNAREs | Q33881676 | ||
Calcineurin links Ca2+ dysregulation with brain aging | Q33947530 | ||
Optimization of formaldehyde cross-linking for protein interaction analysis of non-tagged integrin beta1 | Q33961172 | ||
The calcineurin signaling network evolves via conserved kinase-phosphatase modules that transcend substrate identity | Q34021964 | ||
Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death. | Q34043163 | ||
Calcineurin determines toxic versus beneficial responses to α-synuclein | Q34120215 | ||
Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity | Q39914071 | ||
Control of macroautophagy by calcium, calmodulin-dependent kinase kinase-beta, and Bcl-2. | Q40179972 | ||
An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast | Q41970961 | ||
Homotypic vacuole fusion in yeast requires organelle acidification and not the V-ATPase membrane domain. | Q42105526 | ||
Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of -synuclein in Parkinson's disease models | Q42711308 | ||
The Rab GTPase Ypt7 is linked to retromer-mediated receptor recycling and fusion at the yeast late endosome | Q42825741 | ||
Yeast cells provide insight into alpha-synuclein biology and pathobiology | Q42988614 | ||
Ca 2+ -dependent autophagy is enhanced by the pharmacological agent PK11195. | Q43079159 | ||
Mitochondrial degradation in acetic acid-induced yeast apoptosis: the role of Pep4 and the ADP/ATP carrier | Q43117448 | ||
Forebrain-specific calcineurin knockout selectively impairs bidirectional synaptic plasticity and working/episodic-like memory | Q43815520 | ||
Characterization of alpha-synuclein aggregation and synergistic toxicity with protein tau in yeast | Q45308122 | ||
Evidence for a partially folded intermediate in alpha-synuclein fibril formation | Q46097239 | ||
Functional mitochondria are required for alpha-synuclein toxicity in aging yeast. | Q46810246 | ||
Post-transplant neurotoxicity: what role do calcineurin inhibitors actually play? | Q48421767 | ||
pH-dependent processing of yeast procarboxypeptidase Y by proteinase A in vivo and in vitro | Q61447128 | ||
Cytosolic acidification stimulates a calcium influx that activates Na(+)-H+ exchange in LLC-PK1 | Q68258899 | ||
Oxidative stress-induced phosphorylation, degradation and aggregation of alpha-synuclein are linked to upregulated CK2 and cathepsin D | Q80831427 | ||
Mitochondrial dysfunction in Parkinson's disease | Q88170868 | ||
The molecular machinery for lysosome biogenesis | Q34194555 | ||
Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. | Q34380191 | ||
Identification of genes affecting vacuole membrane fragmentation in Saccharomyces cerevisiae | Q34577025 | ||
In vivo demonstration that alpha-synuclein oligomers are toxic | Q34652122 | ||
α-Synuclein impairs macroautophagy: implications for Parkinson's disease. | Q35005567 | ||
The propeptide of yeast cathepsin D inhibits programmed necrosis. | Q35064998 | ||
Lifespan extension by methionine restriction requires autophagy-dependent vacuolar acidification | Q35160736 | ||
Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress | Q35586574 | ||
Vacuole acidification is required for trans-SNARE pairing, LMA1 release, and homotypic fusion | Q35642673 | ||
Aggregation of alpha-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies | Q35764504 | ||
Vacuolar H+-ATPase (V-ATPase) Promotes Vacuolar Membrane Permeabilization and Nonapoptotic Death in Stressed Yeast | Q36003655 | ||
Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease | Q36100354 | ||
The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models | Q36603128 | ||
Vacuolar and plasma membrane proton pumps collaborate to achieve cytosolic pH homeostasis in yeast | Q36761876 | ||
TFEB-mediated autophagy rescues midbrain dopamine neurons from α-synuclein toxicity | Q36835587 | ||
Bleach gel: A simple agarose gel for analyzing RNA quality | Q36975439 | ||
Acetate-induced apoptosis in colorectal carcinoma cells involves lysosomal membrane permeabilization and cathepsin D release | Q37073584 | ||
Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo. | Q37102231 | ||
The yeast lysosome-like vacuole: endpoint and crossroads | Q37266848 | ||
A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor | Q37386983 | ||
Blockade of protein phosphatase 2B activity in the amygdala increases anxiety- and depression-like behaviors in mice | Q37455947 | ||
The Role of Autophagy in Parkinson's Disease | Q37999796 | ||
Lysosome-dependent pathways as a unifying theme in Parkinson's disease. | Q38038561 | ||
Dysfunction of the autophagy/lysosomal degradation pathway is a shared feature of the genetic synucleinopathies | Q38107478 | ||
Lysosomal Dysfunction and α-Synuclein Aggregation in Parkinson's Disease: Diagnostic Links. | Q38753762 | ||
Cathepsin D protects colorectal cancer cells from acetate-induced apoptosis through autophagy-independent degradation of damaged mitochondria | Q38862588 | ||
Corynoxine, a natural autophagy enhancer, promotes the clearance of alpha-synuclein via Akt/mTOR pathway | Q39024437 | ||
Calcium: Alpha-Synuclein Interactions in Alpha-Synucleinopathies | Q39075636 | ||
From the baker to the bedside: yeast models of Parkinson's disease. | Q39208122 | ||
The emerging role of retromer in neuroprotection | Q39235096 | ||
Glucocorticoids downregulate Fyn and inhibit IP3-mediated calcium signaling to promote autophagy in T lymphocytes | Q39660061 | ||
AMPK-independent induction of autophagy by cytosolic Ca2+ increase. | Q39746175 | ||
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. | Q39867616 | ||
P921 | main subject | Synuclein | Q24767155 |
P304 | page(s) | 207 | |
P577 | publication date | 2017-06-30 | |
P1433 | published in | Frontiers in Molecular Neuroscience | Q27721913 |
P1476 | title | The Coordinated Action of Calcineurin and Cathepsin D Protects Against α-Synuclein Toxicity | |
P478 | volume | 10 |
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Q99202584 | Membrane-tethering of cytochrome c accelerates regulated cell death in yeast |
Q91795634 | Stable and destabilized GFP reporters to monitor calcineurin activity in Saccharomyces cerevisiae |
Q47112563 | Taking out the garbage: cathepsin D and calcineurin in neurodegeneration. |
Q55442883 | The Enzymatic Core of the Parkinson’s Disease-Associated Protein LRRK2 Impairs Mitochondrial Biogenesis in Aging Yeast. |
Q55262989 | Yeast as a tool to identify anti-aging compounds. |
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