review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Sebastian Hofer | Q56784490 |
Andreas Zimmermann | Q60609278 | ||
P2093 | author name string | Didac Carmona-Gutierrez | |
Frank Madeo | |||
Katharina Kainz | |||
Tobias Pendl | |||
P2860 | cites work | mTOR regulates lysosomal ATP-sensitive two-pore Na(+) channels to adapt to metabolic state | Q24315101 |
Attenuation of polyglutamine-induced toxicity by enhancement of mitochondrial OXPHOS in yeast and fly models of aging. | Q37698147 | ||
The molecular and cellular action properties of artemisinins: what has yeast told us? | Q37698286 | ||
How do yeast sense mitochondrial dysfunction? | Q37698326 | ||
Histone modifications as regulators of life and death in Saccharomyces cerevisiae | Q37705706 | ||
Evidence for the hallmarks of human aging in replicatively aging yeast. | Q37705710 | ||
Extension of chronological life span in yeast by decreased TOR pathway signaling | Q24539948 | ||
Extending healthy life span--from yeast to humans | Q24599191 | ||
Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes | Q24616983 | ||
Replicative and chronological aging in Saccharomyces cerevisiae. | Q24633177 | ||
Rapamycin fed late in life extends lifespan in genetically heterogeneous mice | Q24647805 | ||
Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models | Q24683059 | ||
The crucial impact of lysosomes in aging and longevity | Q26749118 | ||
Growth factors, nutrient signaling, and cardiovascular aging | Q26852243 | ||
The search for antiaging interventions: from elixirs to fasting regimens | Q26863497 | ||
Aging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicans | Q26866874 | ||
Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release | Q27340068 | ||
Resveratrol improves health and survival of mice on a high-calorie diet | Q27860950 | ||
Regulation of longevity and stress resistance by Sch9 in yeast | Q27929987 | ||
The cell death protease Kex1p is essential for hypochlorite-induced apoptosis in yeast. | Q27937978 | ||
A caspase-related protease regulates apoptosis in yeast | Q27938405 | ||
Role of gamma-glutamyltranspeptidase in detoxification of xenobiotics in the yeasts Hansenula polymorpha and Saccharomyces cerevisiae. | Q27938544 | ||
The pleitropic drug ABC transporters from Saccharomyces cerevisiae. | Q27938933 | ||
A new dominant peroxiredoxin allele identified by whole-genome re-sequencing of random mutagenized yeast causes oxidant-resistance and premature aging | Q27939527 | ||
Essential role for autophagy in life span extension | Q28085050 | ||
The hallmarks of aging | Q28131641 | ||
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan | Q28203572 | ||
Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening | Q28210511 | ||
A human tRNA synthetase is a potent PARP1-activating effector target for resveratrol | Q28254419 | ||
Endonuclease G mediates α-synuclein cytotoxicity during Parkinson's disease | Q28300290 | ||
Substrate-specific activation of sirtuins by resveratrol | Q28305166 | ||
Identification of a small molecule inhibitor of Sir2p | Q28344005 | ||
Genome-wide consequences of deleting any single gene | Q28383348 | ||
Identification and characterization of antifungal compounds using a Saccharomyces cerevisiae reporter bioassay | Q28483330 | ||
Ink4a/Arf expression is a biomarker of aging | Q28570483 | ||
Efforts to make and apply humanized yeast | Q28602193 | ||
Induction of autophagy by spermidine promotes longevity | Q29614498 | ||
The mechanisms of vesicle budding and fusion | Q29615234 | ||
Ribosomal protein S6 kinase 1 signaling regulates mammalian life span | Q29615975 | ||
Genome-wide analysis of functional sirtuin chromatin targets in yeast | Q30412508 | ||
A microarray-based genetic screen for yeast chronological aging factors | Q30436367 | ||
The genetic architecture in Saccharomyces cerevisiae that contributes to variation in drug response to the antifungals benomyl and ketoconazole. | Q53313492 | ||
Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span. | Q53582417 | ||
p16INK4A is a robust in vivo biomarker of cellular aging in human skin. | Q53605130 | ||
Chemical genetic screen in fission yeast reveals roles for vacuolar acidification, mitochondrial fission, and cellular GMP levels in lifespan extension. | Q54442297 | ||
The therapeutic potential of resveratrol: a review of clinical trials. | Q55151370 | ||
Ceramide triggers metacaspase-independent mitochondrial cell death in yeast | Q58350041 | ||
Yeast as an honorary mammal | Q74071835 | ||
Yeast as a model system for anticancer drug discovery | Q80146770 | ||
Type 5 adenylyl cyclase disruption increases longevity and protects against stress | Q80700459 | ||
Aminoguanidine delays the replicative senescence of human diploid fibroblasts. | Q46859641 | ||
Defects in N-glycosylation induce apoptosis in yeast | Q46899354 | ||
A yeast-based cytotoxicity and genotoxicity assay for environmental monitoring using novel portable instrumentation | Q47249706 | ||
A Novel Sterol-Signaling Pathway Governs Azole Antifungal Drug Resistance and Hypoxic Gene Repression in Saccharomyces cerevisiae. | Q47274009 | ||
Guidelines and recommendations on yeast cell death nomenclature. | Q47550728 | ||
Cell differentiation within a yeast colony: metabolic and regulatory parallels with a tumor-affected organism. | Q47804989 | ||
Glycation inhibitors extend yeast chronological lifespan by reducing advanced glycation end products and by back regulation of proteins involved in mitochondrial respiration | Q47987670 | ||
Spermidine in health and disease. | Q48163525 | ||
The integrated stress response in budding yeast lifespan extension. | Q49278406 | ||
Methods to Assess Autophagy and Chronological Aging in Yeast. | Q50207016 | ||
Effect of Low-Dose Rapamycin on Senescence Markers and Physical Functioning in Older Adults with Coronary Artery Disease: Results of a Pilot Study. | Q51305911 | ||
Transcriptional remodeling in response to transfer upon carbon-limited or metformin-supplemented media in S. cerevisiae and its effect on chronological life span. | Q51619207 | ||
Age-dependent accumulation of advanced glycation end-products in adult Drosophila melanogaster. | Q52563298 | ||
New rapid screening method for anti-aging compounds using budding yeast and identification of beauveriolide I as a potent active compound. | Q53157400 | ||
Autophagy extends lifespan via vacuolar acidification | Q37705715 | ||
Simple is good: yeast models of neurodegeneration. | Q37767749 | ||
Cytochrome P450 enzymes in the fungal kingdom | Q37771488 | ||
Mitochondria, reactive oxygen species, and chronological aging: a message from yeast | Q37925178 | ||
Chronological aging in Saccharomyces cerevisiae | Q37957577 | ||
Chaperone networks in protein disaggregation and prion propagation | Q38009622 | ||
Cytochrome P450 enzymes in drug metabolism: regulation of gene expression, enzyme activities, and impact of genetic variation | Q38075335 | ||
Aging and differentiation in yeast populations: elders with different properties and functions | Q38151967 | ||
Lipids and cell death in yeast | Q38151973 | ||
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family in multidrug resistance: A review of the past decade | Q38616109 | ||
Studying the replicative life span of yeast cells | Q38729455 | ||
The budding yeast Saccharomyces cerevisiae as a model organism: possible implications for gerontological studies. | Q38749590 | ||
Caloric Restriction Mimetics Enhance Anticancer Immunosurveillance | Q38758370 | ||
Intracellular pH Modulates Autophagy and Mitophagy. | Q38792770 | ||
The Substrate Specificity of Sirtuins | Q38810867 | ||
The frequency of yeast [PSI+] prion formation is increased during chronological ageing | Q38823866 | ||
Yeast proteinopathy models: a robust tool for deciphering the basis of neurodegeneration. | Q39208066 | ||
Live fast, die soon: cell cycle progression and lifespan in yeast cells | Q39208079 | ||
From the baker to the bedside: yeast models of Parkinson's disease. | Q39208122 | ||
Autophagy: machinery and regulation | Q39208155 | ||
Signaling pathways and posttranslational modifications of tau in Alzheimer's disease: the humanization of yeast cells | Q39208164 | ||
Exacerbating and reversing lysosomal storage diseases: from yeast to humans | Q40038745 | ||
The Coordinated Action of Calcineurin and Cathepsin D Protects Against α-Synuclein Toxicity. | Q40998960 | ||
Cellular responses of Saccharomyces cerevisiae at near-zero growth rates: transcriptome analysis of anaerobic retentostat cultures. | Q41138196 | ||
Yeast as a model system to screen purine derivatives against human CDK1 and CDK2 kinases | Q41648702 | ||
Autophagy is a critical regulator of memory CD8(+) T cell formation | Q41668622 | ||
Autophagy is required for extension of yeast chronological life span by rapamycin | Q41679914 | ||
Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons | Q41774391 | ||
Expression of a human cytochrome p450 in yeast permits analysis of pathways for response to and repair of aflatoxin-induced DNA damage | Q41834934 | ||
Somatic growth, aging, and longevity | Q41907365 | ||
A yeast mutant showing diagnostic markers of early and late apoptosis | Q42065466 | ||
Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs | Q42119629 | ||
A yeast-based model of alpha-synucleinopathy identifies compounds with therapeutic potential | Q42167795 | ||
Recovery from rapamycin: drug-insensitive activity of yeast target of rapamycin complex 1 (TORC1) supports residual proliferation that dilutes rapamycin among progeny cells. | Q42212596 | ||
Yeast screening platform identifies FDA-approved drugs that reduce Aβ oligomerization | Q42316646 | ||
Anti-inflammatory and antioxidant effects of resveratrol in healthy smokers a randomized, double-blind, placebo-controlled, cross-over trial | Q42713454 | ||
Chronological aging leads to apoptosis in yeast | Q42774835 | ||
Oxygen stress: a regulator of apoptosis in yeast | Q42797452 | ||
Identification of ACA-28, a 1'-acetoxychavicol acetate analogue compound, as a novel modulator of ERK MAPK signaling, which preferentially kills human melanoma cells. | Q42800772 | ||
Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity | Q43079790 | ||
Elevation of endogenous sphingolipid long-chain base phosphates kills Saccharomyces cerevisiae cells | Q43857471 | ||
Regulation of longevity and stress resistance: a molecular strategy conserved from yeast to humans? | Q44095372 | ||
Restoring polyamines protects from age-induced memory impairment in an autophagy-dependent manner | Q44800085 | ||
A common highly conserved cadmium detoxification mechanism from bacteria to humans: heavy metal tolerance conferred by the ATP-binding cassette (ABC) transporter SpHMT1 requires glutathione but not metal-chelating phytochelatin peptides | Q46215291 | ||
A genome-wide screen for FTY720-sensitive mutants reveals genes required for ROS homeostasis | Q46242463 | ||
A method for high-throughput quantitative analysis of yeast chronological life span | Q46722596 | ||
High-throughput screening for growth inhibitors using a yeast model of familial paraganglioma | Q30457876 | ||
Insights into TOR function and rapamycin response: chemical genomic profiling by using a high-density cell array method. | Q30852003 | ||
High-throughput screening for fatty acid uptake inhibitors in humanized yeast identifies atypical antipsychotic drugs that cause dyslipidemias | Q33302249 | ||
Detection of compounds that rescue Rab1-synuclein toxicity | Q33326182 | ||
An integrated platform of genomic assays reveals small-molecule bioactivities | Q33351287 | ||
Compounds from an unbiased chemical screen reverse both ER-to-Golgi trafficking defects and mitochondrial dysfunction in Parkinson's disease models | Q33521022 | ||
Recombinant yeast screen for new inhibitors of human acetyl-CoA carboxylase 2 identifies potential drugs to treat obesity | Q33571309 | ||
Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons | Q33616462 | ||
A simple microfluidic platform to study age-dependent protein abundance and localization changes in Saccharomyces cerevisiae | Q33658227 | ||
Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster | Q33665807 | ||
Effects of resveratrol on cerebral blood flow variables and cognitive performance in humans: a double-blind, placebo-controlled, crossover investigation. | Q34107721 | ||
Candida Albicans: a molecular revolution built on lessons from budding yeast | Q34161985 | ||
An overview on glutathione in versus non-conventional yeasts | Q34191410 | ||
The role of glutathione-S-transferase in anti-cancer drug resistance | Q34272162 | ||
Metformin improves healthspan and lifespan in mice | Q34360789 | ||
Growth signaling promotes chronological aging in budding yeast by inducing superoxide anions that inhibit quiescence | Q34361242 | ||
Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. | Q34380191 | ||
Cardioprotection and lifespan extension by the natural polyamine spermidine. | Q34544613 | ||
Advanced glycation end products: sparking the development of diabetic vascular injury | Q34555042 | ||
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome | Q34600785 | ||
SOD2 functions downstream of Sch9 to extend longevity in yeast | Q34616845 | ||
Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates. | Q34624641 | ||
Target identification and mechanism of action in chemical biology and drug discovery | Q34626974 | ||
Yeast as a biosensor of detoxification: a tool for identifying new compounds that revert multidrug resistance. | Q34686134 | ||
Separation of mother and daughter cells | Q34694887 | ||
Quantification of genetically controlled cell death in budding yeast | Q34754970 | ||
Screen for small molecules increasing the mitochondrial membrane potential | Q34836339 | ||
Spermidine induces autophagy by inhibiting the acetyltransferase EP300. | Q35079516 | ||
Phosphatidylethanolamine positively regulates autophagy and longevity | Q35079520 | ||
Protein folding and quality control in the endoplasmic reticulum: Recent lessons from yeast and mammalian cell systems | Q35160159 | ||
Chemogenomic profiling: identifying the functional interactions of small molecules in yeast | Q35554300 | ||
Target of rapamycin (TOR) in nutrient signaling and growth control | Q35620394 | ||
Yeast as a system for modeling mitochondrial disease mechanisms and discovering therapies | Q35687142 | ||
Different 8-hydroxyquinolines protect models of TDP-43 protein, α-synuclein, and polyglutamine proteotoxicity through distinct mechanisms | Q35763165 | ||
A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay | Q35794951 | ||
H3K36 methylation promotes longevity by enhancing transcriptional fidelity | Q35879041 | ||
Identification of a small molecule yeast TORC1 inhibitor with a multiplex screen based on flow cytometry | Q35903219 | ||
High-throughput analysis of yeast replicative aging using a microfluidic system | Q35910113 | ||
Using Yeast Transposon-Insertion Libraries for Phenotypic Screening and Protein Localization | Q36037048 | ||
Continuous beer fermentation using immobilized yeast cell bioreactor systems. | Q36149046 | ||
The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models | Q36603128 | ||
The role of mitochondria in aging | Q36638140 | ||
Measurement of lifespan in Drosophila melanogaster | Q36639173 | ||
Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans | Q36658296 | ||
Metformin: an old but still the best treatment for type 2 diabetes | Q36715464 | ||
Resveratrol for primary prevention of atherosclerosis: clinical trial evidence for improved gene expression in vascular endothelium. | Q36823957 | ||
Development of the FUN-1 family of fluorescent probes for vacuole labeling and viability testing of yeasts | Q36869468 | ||
A Comprehensive Analysis of Replicative Lifespan in 4,698 Single-Gene Deletion Strains Uncovers Conserved Mechanisms of Aging. | Q36888608 | ||
Pathways change in expression during replicative aging in Saccharomyces cerevisiae | Q36924456 | ||
Epigenetic silencing mediates mitochondria stress-induced longevity | Q36960145 | ||
Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis | Q37076826 | ||
Drug-induced apoptosis in yeast | Q37077860 | ||
Replicative aging in yeast: the means to the end | Q37212205 | ||
Passage of molecules through yeast cell walls: a brief essay-review | Q37249507 | ||
Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet. | Q37320110 | ||
Yeast life span extension by depletion of 60s ribosomal subunits is mediated by Gcn4. | Q37359194 | ||
Targeting mTOR with rapamycin: one dose does not fit all | Q37409171 | ||
Fission yeast and other yeasts as emergent models to unravel cellular aging in eukaryotes. | Q37624333 | ||
Apoptosis in yeast: triggers, pathways, subroutines | Q37675909 | ||
Rapamycin: one drug, many effects | Q37679469 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P433 | issue | 6 | |
P921 | main subject | eukaryote | Q19088 |
yeast | Q45422 | ||
biomedical investigative technique | Q66648976 | ||
small molecule libraries | Q50573438 | ||
P577 | publication date | 2018-09-01 | |
P1433 | published in | FEMS Yeast Research | Q15751211 |
P1476 | title | Yeast as a tool to identify anti-aging compounds. | |
P478 | volume | 18 |
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