Noncytolytic CD8 T cell-mediated suppression of HIV replication

scientific article published on January 1997

Noncytolytic CD8 T cell-mediated suppression of HIV replication is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/BF00813503
P698PubMed publication ID9089954

P50authorSimon F LaceyQ56978267
Kent J. WeinholdQ109935303
Dani BolognesiQ109936341
P2093author name stringChen CH
Greenberg ML
P2860cites workHigh levels of HIV-1 in plasma during all stages of infection determined by competitive PCRQ22242246
Isolation of a T-Lymphotropic Retrovirus from a Patient at Risk for Acquired Immune Deficiency Syndrome (AIDS)Q22242256
HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled ReceptorQ22242268
Identification of a major co-receptor for primary isolates of HIV-1Q22251282
Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infectionQ24645815
Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndromeQ24648628
Long-term HIV-1 infection without immunologic progressionQ28242263
The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirusQ28259668
HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of diseaseQ28267375
Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cellsQ28270680
Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infectionQ28304764
Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infectionQ28304773
T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAVQ28646817
Frequent Detection and Isolation of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and at Risk for AIDSQ29614260
HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5Q29616094
The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brainQ29618472
The immunopathogenesis of human immunodeficiency virus infectionQ34060285
CD8+ cell anti-HIV activity correlates with the clinical state of the infected individualQ34185306
Isolation of Lymphocytopathic Retroviruses from San Francisco Patients with AIDSQ34250436
CD8+ lymphocytes can control HIV infection in vitro by suppressing virus replicationQ34390292
CD8+ T cells suppress human immunodeficiency virus replication by inhibiting viral transcriptionQ34585299
CD8+ T lymphocytes of African green monkeys secrete an immunodeficiency virus-suppressing lymphokineQ35621878
Defective accessory genes in a human immunodeficiency virus type 1-infected long-term survivor lacking recoverable virusQ35841354
A cytotoxic T lymphocyte inhibits acquired immunodeficiency syndrome virus replication in peripheral blood lymphocytesQ36356023
Inhibition of human immunodeficiency virus replication in acutely infected CD4+ cells by CD8+ cells involves a noncytotoxic mechanismQ36820948
Stable growth transformation of human T lymphocytes by herpesvirus saimiriQ36939191
Human immunodeficiency virus type 1 mRNA expression in peripheral blood cells predicts disease progression independently of the numbers of CD4+ lymphocytesQ37558815
Viral DNA and mRNA expression correlate with the stage of human immunodeficiency virus (HIV) type 1 infection in humans: evidence for viral replication in all stages of HIV diseaseQ40049075
Oligoclonal CD8 lymphocytes from persons with asymptomatic human immunodeficiency virus (HIV) type 1 infection inhibit HIV-1 replication.Q40971485
Relative resistance to HIV-1 infection of CD4 lymphocytes from persons who remain uninfected despite multiple high-risk sexual exposureQ41212897
Suppression of activation of the human immunodeficiency virus long terminal repeat by CD8+ T cells is not lentivirus specificQ41276077
Suppression of HIV replication by CD8+ cell clones derived from HIV-infected and uninfected individualsQ41414397
The characterization of non-progressors: long-term HIV-1 infection with stable CD4+ T-cell levels.Q41531784
Detection of HIV-1 DNA and messenger RNA in individual cells by PCR-driven in situ hybridization and flow cytometryQ41553819
Inhibition of cellular activation of retroviral replication by CD8+ T cells derived from non-human primatesQ41571158
In vitro replication of HIV-1 in naturally infected CD4+ T cells is inhibited by rIFN alpha 2 and by a soluble factor secreted by activated CD8+ T cells, but not by rIFN beta, rIFN gamma, or recombinant tumor necrosis factor-alphaQ41707962
Plasma viremia in human immunodeficiency virus infectionQ43513599
CD8+ T cells inhibit HIV replication in naturally infected CD4+ T cells. Evidence for a soluble inhibitorQ43730414
Reliable isolation of human immunodeficiency virus from cultures of naturally infected CD4+ T cellsQ43875706
A diffusible lymphokine produced by CD8+ T lymphocytes suppresses HIV replication.Q44141073
Suppression of human immunodeficiency virus replication by CD8+ cells from infected and uninfected chimpanzeesQ44246260
Studies in subjects with long-term nonprogressive human immunodeficiency virus infectionQ44369963
Predictive markers for the acquired immunodeficiency syndrome (AIDS) in hemophiliacs: persistence of p24 antigen and low T4 cell countQ44658885
Predictors for non- and slow progression in human immunodeficiency virus (HIV) type 1 infection: low viral RNA copy numbers in serum and maintenance of high HIV-1 p24-specific but not V3-specific antibody levelsQ45786423
Isolation of human immunodeficiency virus (HIV) from plasma during primary HIV infectionQ45831397
Suppression of simian immunodeficiency virus replication in vitro by CD8+ lymphocytesQ45839300
Quantitation of human immunodeficiency virus type 1 in the blood of infected personsQ45844274
High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infectionQ45854355
Transient High Levels of Viremia in Patients with Primary Human Immunodeficiency Virus Type 1 InfectionQ45856562
CD8+ T cells from HIV-1-infected individuals inhibit acute infection by human and primate immunodeficiency virusesQ46494799
Effect of cytokines on HIV replication in CD4+ lymphocytes: lack of identity with the CD8+ cell antiviral factorQ46550585
HIV suppression by interleukin-16.Q48068605
Long-term symptomless HIV-1 infection in recipients of blood products from a single donorQ57076560
Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDSQ59057787
CD8+ and CD45RA+ human peripheral blood lymphocytes are potent sources of macrophage inflammatory protein 1α, interleukin-8 and RANTESQ59200610
Identification of multiple and distinct CD8+ T cell suppressor activities: dichotomy between infected and uninfected individuals, evolution with progression of disease, and sensitivity to gamma irradiationQ71151752
Inhibition of HIV replication by CD8+ T cells correlates with CD4 counts and clinical stage of diseaseQ71634193
Quantitation of HIV-1 RNA in plasma predicts outcome after seroconversionQ72624142
CD8+ T lymphocyte-mediated inhibition of HIV-1 long terminal repeat transcription: a novel antiviral mechanismQ72782422
P433issue3
P304page(s)355-369
P577publication date1997-01-01
P1433published inSeminars in ImmunopathologyQ15724576
P1476titleNoncytolytic CD8 T cell-mediated suppression of HIV replication
P478volume18

Reverse relations

cites work (P2860)
Q35114369CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression.
Q37157103Noncytotoxic suppression of human immunodeficiency virus type 1 transcription by exosomes secreted from CD8+ T cells
Q30445480Novel function of prothymosin alpha as a potent inhibitor of human immunodeficiency virus type 1 gene expression in primary macrophages
Q36576683The CXC chemokine stromal cell-derived factor 1 is not responsible for CD8+ T cell suppression of syncytia-inducing strains of HIV-1.
Q45012988Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P).

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