Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma

scientific article published on October 1994

Synergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1015560033
P356DOI10.1038/371674A0
P698PubMed publication ID7935812
P5875ResearchGate publication ID15263049

P50authorRobert GalloQ469904
P2093author name stringRaffeld M
Brady JN
Ensoli B
Gendelman R
Markham P
Colombini S
Fiorelli V
Cafaro A
Chang HK
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Cancer metastasis and angiogenesis: An imbalance of positive and negative regulationQ36618743
Extracellular matrix and cell shape: potential control points for inhibition of angiogenesisQ36715134
Role of the alpha v beta 3 integrin in human melanoma cell invasionQ36847392
Interleukin 1 regulates heparin-binding growth factor 2 gene expression in vascular smooth muscle cellsQ37365521
The heparin-binding (fibroblast) growth factor family of proteinsQ38286731
Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patientsQ41734588
Kaposi's sarcoma cells: long-term culture with growth factor from retrovirus-infected CD4+ T cells.Q52833089
AIDS-Kaposi's sarcoma-derived cells express cytokines with autocrine and paracrine growth effects.Q54565305
Angiogenic properties of Kaposi's sarcoma-derived cells after long-term culture in vitro.Q55242415
The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic miceQ59060595
The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequenceQ24561727
Role of laminin and basement membrane in the morphological differentiation of human endothelial cells into capillary-like structuresQ24679747
Integrins: versatility, modulation, and signaling in cell adhesionQ27860844
Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDSQ28262859
The role of mononuclear phagocytes in HTLV-III/LAV infectionQ29618676
Requirement of vascular integrin alpha v beta 3 for angiogenesisQ29619681
Angiogenic factorsQ29620582
Human immunodeficiency virus (HIV) transcripts identified in HIV-related psoriasis and Kaposi's sarcoma lesionsQ33246074
The natural history of Kaposi's sarcoma in the acquired immunodeficiency syndromeQ34693731
Tat-mediated delivery of heterologous proteins into cellsQ34991904
In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases.Q36220034
P433issue6499
P407language of work or nameEnglishQ1860
P304page(s)674-680
P577publication date1994-10-01
P1433published inNatureQ180445
P1476titleSynergy between basic fibroblast growth factor and HIV-1 Tat protein in induction of Kaposi's sarcoma
P478volume371

Reverse relations

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Q33724002Perspective on Kaposi's sarcoma: facts, concepts, and conjectures
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Q28140820Phenotypic alterations in Kaposi's sarcoma cells by antisense reduction of perlecan
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Q34295807Reactivation and role of HHV-8 in Kaposi's sarcoma initiation
Q36135122Recent insights into the pathogenesis of Kaposi's sarcoma
Q34226294Reciprocal modulations between p53 and Tat of human immunodeficiency virus type 1
Q40832278Reciprocal regulatory interaction between human herpesvirus 8 and human immunodeficiency virus type 1.
Q36489392Reciprocal transactivation between HIV-1 and other human viruses
Q35866513Recombinant human immunodeficiency virus type 1 genomes with tat unconstrained by overlapping reading frames reveal residues in Tat important for replication in tissue culture.
Q58276496Regression of AIDS-related Kaposi's sarcoma following antiretroviral therapy with protease inhibitors: biological correlates of clinical outcome
Q53911175Role of Pax2 in apoptosis resistance and proinvasive phenotype of Kaposi's sarcoma cells.
Q22008760Role of alphavbeta3 integrin in the activation of vascular endothelial growth factor receptor-2.
Q41372610Role of soluble mediators in angiogenesis
Q45372146Salivary shedding of HHV-8 in people infected or not by human immunodeficiency virus 1
Q40439853Secreted complement regulatory protein clusterin interacts with dengue virus nonstructural protein 1.
Q71253864Seeking the cause of Kaposi's sarcoma
Q41335848Sensitization of T cells to CD95-mediated apoptosis by HIV-1 Tat and gp120.
Q38304360Signalling properties of an HIV-encoded angiogenic peptide mimicking vascular endothelial growth factor activity.
Q73236064Spectroscopic investigations of HIV-1 trans-activator and related peptides in aqueous solutions
Q74641832Stimulation of Kaposi's sarcoma cell growth by urine from women in early pregnancy, the current source for clinical-grade human chorionic gonadotropin preparations
Q35773499Strong expression of kinase insert domain-containing receptor, a vascular permeability factor/vascular endothelial growth factor receptor in AIDS-associated Kaposi's sarcoma and cutaneous angiosarcoma.
Q53406374Sustained angiogenesis enables in vivo transplantation of mucocutaneous derived AIDS-related Kaposi's sarcoma cells in murine hosts.
Q37415434Taking a hard look at the pathogenesis of childhood HIV-associated nephropathy
Q24683211Tat protein induces self-perpetuating permissivity for productive HIV-1 infection
Q24524076Tat protein of human immunodeficiency virus type 1 induces interleukin-10 in human peripheral blood monocytes: implication of protein kinase C-dependent pathway
Q35040673The HIV-1 Tat protein induces the activation of CD8+ T cells and affects in vivo the magnitude and kinetics of antiviral responses
Q41247263The angiogenesis induced by HIV-1 tat protein is mediated by the Flk-1/KDR receptor on vascular endothelial cells.
Q33974601The basic domain of HIV-tat transactivating protein is essential for its targeting to lipid rafts and regulating fibroblast growth factor-2 signaling in podocytes isolated from children with HIV-1-associated nephropathy
Q35741522The broad-spectrum anti-DNA virus agent cidofovir inhibits lung metastasis of virus-independent, FGF2-driven tumors.
Q54768257The detection and comparison of angiogenesis-associated factors in pyogenic granuloma by immunohistochemistry.
Q71549035The expression of p53 in patients with coexistent breast carcinoma and malignant melanoma
Q24534479The helical domain of GBP-1 mediates the inhibition of endothelial cell proliferation by inflammatory cytokines.
Q45764762The human immunodeficiency virus type-1 (HIV-1) Tat protein and Bcl-2 gene expression
Q37026769The microenvironment of AIDS-related diffuse large B-cell lymphoma provides insight into the pathophysiology and indicates possible therapeutic strategies
Q33864926The presence of anti-Tat antibodies in HIV-infected individuals is associated with containment of CD4+ T-cell decay and viral load, and with delay of disease progression: results of a 3-year cohort study
Q61566187The relevance of apoptosis to AIDS pathogenesis
Q45880112The role of cytokines in cancer
Q64882933The role of immunosuppression and immune-activation in classic Kaposi's sarcoma.
Q28476094Therapeutic immunization with HIV-1 Tat reduces immune activation and loss of regulatory T-cells and improves immune function in subjects on HAART
Q22251070Therapy Insight: AIDS-related malignancies—the influence of antiviral therapy on pathogenesis and management
Q74366112Thiol redox modulation of tumor necrosis factor-alpha responsiveness in cultured AIDS-related Kaposi's sarcoma cells
Q58906633Thrombospondin-1 inhibits Kaposi's sarcoma (KS) cell and HIV-1 Tat-induced angiogenesis and is poorly expressed in KS lesions
Q37217223Thymidine phosphorylase expression in Kaposi sarcoma
Q83564526Transfer of the ability of HIV-1 Tat to raise an adjuvant-free humoral immune response to unrelated antigens
Q35110917Treatment of gammaherpesvirus-related neoplastic disorders in the immunosuppressed host
Q24315143Tumorigenesis and metastasis of neoplastic Kaposi's sarcoma cell line in immunodeficient mice blocked by a human pregnancy hormone
Q37348840Tumorigenesis by human herpesvirus 8 vGPCR is accelerated by human immunodeficiency virus type 1 Tat.
Q35215799Use of HIV protease inhibitors to block Kaposi's sarcoma and tumour growth
Q35715660Use of boosted protease inhibitors reduces Kaposi sarcoma incidence among male veterans with HIV infection
Q45012988Vaccination with DNA containing tat coding sequences and unmethylated CpG motifs protects cynomolgus monkeys upon infection with simian/human immunodeficiency virus (SHIV89.6P).
Q35765203Vascular endothelial growth factor and basic fibroblast growth factor present in Kaposi's sarcoma (KS) are induced by inflammatory cytokines and synergize to promote vascular permeability and KS lesion development
Q35782711Vascular endothelial growth factor regulates angiogenesis and vascular permeability in Kaposi's sarcoma
Q35967211Vascular endothelial growth factor/vascular permeability factor is an autocrine growth factor for AIDS-Kaposi sarcoma
Q38666881Viral effects on the content and function of extracellular vesicles.
Q74581561Viral infections in the mouth
Q37871527Viruses as key regulators of angiogenesis
Q37220038What does the structure-function relationship of the HIV-1 Tat protein teach us about developing an AIDS vaccine?
Q71783262β2‐microglobulin expression of AIDS‐related and classical Kaposi's sarcoma

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