SMAD versus non-SMAD signaling is determined by lateral mobility of bone morphogenetic protein (BMP) receptors

scientific article published on 7 September 2012

SMAD versus non-SMAD signaling is determined by lateral mobility of bone morphogenetic protein (BMP) receptors is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.M112.387639
P932PMC publication ID3501045
P698PubMed publication ID22961979

P50authorPeter FratzlQ18412191
Petra KnausQ28324737
Peter A KreuzalerQ63762484
P2093author name stringMonika Zelman-Femiak
Asja Guzman
Petra Knaus
Gregory S Harms
Sandra Paschkowsky
Jan H Boergermann
P2860cites workDRAGON, a bone morphogenetic protein co-receptorQ24292739
The type I TGF-beta receptor engages TRAF6 to activate TAK1 in a receptor kinase-independent mannerQ24308947
Dynamics and interaction of caveolin-1 isoforms with BMP-receptorsQ24338470
Bone morphogenetic protein receptor complexes on the surface of live cells: a new oligomerization mode for serine/threonine kinase receptorsQ24548576
Bone morphogenetic protein-9 is a circulating vascular quiescence factorQ24657942
Characterization of bone morphogenetic protein-6 signaling pathways in osteoblast differentiationQ28145299
Interaction between two adapter proteins, PAG and EBP50: a possible link between membrane rafts and actin cytoskeletonQ28202663
Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoterQ28208212
PDK1 nucleates T cell receptor-induced signaling complex for NF-kappaB activationQ28242875
Bone morphogenetic protein receptors and signal transductionQ28258965
Biochemical and functional characterization of the Ror2/BRIb receptor complexQ28306387
Paradigm Shift of the Plasma Membrane Concept from the Two-Dimensional Continuum Fluid to the Partitioned Fluid: High-Speed Single-Molecule Tracking of Membrane MoleculesQ29011044
Different routes of bone morphogenic protein (BMP) receptor endocytosis influence BMP signalingQ30478289
Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membraneQ30499739
Q-Gene: processing quantitative real-time RT-PCR dataQ30813293
Platelet-derived growth factor activates mitogen-activated protein kinase in isolated caveolaeQ33718468
Single-molecule imaging of EGFR signalling on the surface of living cellsQ33892648
Neogenin regulation of BMP-induced canonical Smad signaling and endochondral bone formationQ34074669
BMP signaling and early embryonic patterning.Q34416108
Microtubules and actin microfilaments regulate lipid raft/caveolae localization of adenylyl cyclase signaling componentsQ34544258
Structure of the ternary signaling complex of a TGF-beta superfamily memberQ34589783
Lipid rafts and plasma membrane microorganization: insights from Ras.Q35683553
Nerve growth factor stimulates the concentration of TrkA within lipid rafts and extracellular signal-regulated kinase activation through c-Cbl-associated proteinQ35950181
Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineageQ36235105
Vav1/Rac-dependent actin cytoskeleton reorganization is required for lipid raft clustering in T cellsQ36294111
Dragon (repulsive guidance molecule b) inhibits IL-6 expression in macrophagesQ36896459
Specific activation of mitogen-activated protein kinase by transforming growth factor-beta receptors in lipid rafts is required for epithelial cell plasticityQ37078617
Recent advances in BMP receptor signalingQ37629355
The extracellular domain of the TGFbeta type II receptor regulates membrane raft partitioning.Q39862772
Critical role for lipid raft-associated Src kinases in activation of PI3K-Akt signallingQ40175298
Kinetics of the initial steps of G protein-coupled receptor-mediated cellular signaling revealed by single-molecule imagingQ40388102
A single residue of GDF-5 defines binding specificity to BMP receptor IB.Q40423467
Requirement of BMP-2-induced phosphatidylinositol 3-kinase and Akt serine/threonine kinase in osteoblast differentiation and Smad-dependent BMP-2 gene transcription.Q40722201
Second cysteine-rich region of epidermal growth factor receptor contains targeting information for caveolae/raftsQ40730492
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolismQ41871982
Formation of stable homomeric and transient heteromeric bone morphogenetic protein (BMP) receptor complexes regulates Smad protein signalingQ42740278
BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity.Q42806559
The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.Q42823613
Activation of p38 Mitogen-Activated Protein Kinase and c-Jun-NH2-Terminal Kinase by BMP-2 and Their Implication in the Stimulation of Osteoblastic Cell DifferentiationQ42834274
Initiation of Smad-dependent and Smad-independent signaling via distinct BMP-receptor complexes.Q44553786
Single-molecule study of lateral mobility of epidermal growth factor receptor 2/HER2 on activationQ46715317
Lateral diffusion of TGF-beta type I receptor studied by single-molecule imaging.Q48916119
Covalent quantum dot receptor linkage via the acyl carrier protein for single-molecule tracking, internalization, and trafficking studiesQ50696892
NHERF-1 and the cytoskeleton regulate the traffic and membrane dynamics of G protein-coupled receptors.Q51796458
X-linked inhibitor of apoptosis protein is an important regulator of vascular endothelial growth factor-dependent bovine aortic endothelial cell survival.Q53547938
Activation of mitogen-activated protein kinase cascades is involved in regulation of bone morphogenetic protein-2-induced osteoblast differentiation in pluripotent C2C12 cellsQ73853205
Selective inhibitory effects of Smad6 on bone morphogenetic protein type I receptorsQ80310310
P433issue47
P407language of work or nameEnglishQ1860
P921main subjectmorphogenesisQ815547
P304page(s)39492-39504
P577publication date2012-09-07
P1433published inJournal of Biological ChemistryQ867727
P1476titleSMAD versus non-SMAD signaling is determined by lateral mobility of bone morphogenetic protein (BMP) receptors
P478volume287

Reverse relations

cites work (P2860)
Q27309218A Novel, Noncanonical BMP Pathway Modulates Synapse Maturation at the Drosophila Neuromuscular Junction
Q91684611AMOT130 drives BMP-SMAD signaling at the apical membrane in polarized cells
Q47237512BMP Signalling at the Crossroad of Liver Fibrosis and Regeneration.
Q38152403BMP growth factor signaling in a biomechanical context
Q36159603BMP-SMAD signalling output is highly regionalized in cardiovascular and lymphatic endothelial networks
Q64917280BMP14 induces tenogenic differentiation of bone marrow mesenchymal stem cells in vitro.
Q35178694BMP2-induced chemotaxis requires PI3K p55γ/p110α-dependent phosphatidylinositol (3,4,5)-triphosphate production and LL5β recruitment at the cytocortex
Q38799538BMPR2 gene therapy for PAH acts via Smad and non-Smad signalling.
Q26746964Bone Morphogenetic Protein 4 Signalling in Neural Stem and Progenitor Cells during Development and after Injury
Q38733364Bone Morphogenetic Protein-Based Therapeutic Approaches
Q39013673Dab2 inhibits the cholesterol-dependent activation of JNK by TGF-β
Q38332401Emerging roles of BMP9 and BMP10 in hereditary hemorrhagic telangiectasia.
Q41661866Endothelial Msx1 transduces hemodynamic changes into an arteriogenic remodeling response
Q92049505Enhanced chondrogenesis from human embryonic stem cells
Q37398464FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney
Q52721263Heparan sulfate antagonism alters bone morphogenetic protein signaling and receptor dynamics, suggesting a mechanism in Hereditary Multiple Exostoses.
Q38176443Initiation and early control of tissue regeneration - bone healing as a model system for tissue regeneration
Q42262102Role of bone morphogenetic proteins in sprouting angiogenesis: differential BMP receptor-dependent signaling pathways balance stalk vs. tip cell competence
Q47951257Transdifferentiation of myoblasts into osteoblasts - possible use for bone therapy
Q28831008Tuning cellular responses to BMP-2 with material surfaces

Search more.