Javier Egea

researcher

Javier Egea is …
instance of (P31):
humanQ5

External links are
P2798Loop ID391178
P496ORCID iD0000-0003-4704-3019
P3829Publons author ID2897383
P1053ResearcherIDA-1694-2008
P1153Scopus author ID7005394797

P734family nameEgeaQ37478928
EgeaQ37478928
EgeaQ37478928
P735given nameJavierQ1142232
JavierQ1142232
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q379510701,8-Naphthyridine derivatives as cholinesterases inhibitors and cell Ca2+ regulators, a multitarget strategy for Alzheimer's disease
Q38195865A review of metal-catalyzed molecular damage: protection by melatonin
Q38969497Agmatine induces Nrf2 and protects against corticosterone effects in hippocampal neuronal cell line
Q38875865Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice
Q46694948Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction
Q88116246Analysis of gene expression profiles of CR80, a neuroprotective 1,8-Naphthyridine
Q38558848Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection
Q37732930Antioxidant, antiinflammatory and neuroprotective actions of chondroitin sulfate and proteoglycans
Q39302882Benzothiazepine CGP37157 and its isosteric 2'-methyl analogue provide neuroprotection and block cell calcium entry
Q46985466Blockade of nicotinic receptors of bovine adrenal chromaffin cells by nanomolar concentrations of atropine
Q43184352Both creatine and its product phosphocreatine reduce oxidative stress and afford neuroprotection in an in vitro Parkinson's model
Q38831694CALHM1 and its polymorphism P86L differentially control Ca²⁺homeostasis, mitogen-activated protein kinase signaling, and cell vulnerability upon exposure to amyloid β.
Q41539324Calcium signalling mediated through α7 and non-α7 nAChR stimulation is differentially regulated in bovine chromaffin cells to induce catecholamine release
Q39459684Chemical and pharmacological studies on enantiomerically pure p-methoxytacripyrines, promising multi-target-directed ligands for the treatment of Alzheimer's disease
Q60462302Chondroitin sulfate reduces cell death of rat hippocampal slices subjected to oxygen and glucose deprivation by inhibiting p38, NFκB and iNOS.
Q46477382ConBr, A Lectin Purified from the Seeds of Canavalia brasiliensis, Protects Against Ischemia in Organotypic Culture of Rat Hippocampus: Potential Implication of Voltage-Gated Calcium Channels.
Q47376955Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].
Q91606402Curcumin reduces renal damage associated with rhabdomyolysis by decreasing ferroptosis-mediated cell death
Q60688922Desensitized Nicotinic Receptors That, However, Afford Cytoprotection in Bovine Chromaffin Cells
Q91906967Early toll-like receptor 4 blockade reduces ROS and inflammation triggered by microglial pro-inflammatory phenotype in rodent and human brain ischaemia models
Q45368696Enantioselective neuroprotective effects of Tacripyrine ITH122 against oxygen and glucose deprivation in rat hippocampal slices
Q51998379Enhancement of secretion by threshold nicotinic stimulation in bovine chromaffin cells.
Q48289531Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia
Q33761211European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).
Q52726532Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS.
Q64072607From single drug targets to synergistic network pharmacology in ischemic stroke
Q46488938Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal cell death
Q44971808Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation
Q54549813Galantamine elicits neuroprotection by inhibiting iNOS, NADPH oxidase and ROS in hippocampal slices stressed with anoxia/reoxygenation.
Q50955863Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions.
Q39334402Guanosine protects human neuroblastoma SH-SY5Y cells against mitochondrial oxidative stress by inducing heme oxigenase-1 via PI3K/Akt/GSK-3β pathway.
Q43297366Haeme oxygenase-1 overexpression via nAChRs and the transcription factor Nrf2 has antinociceptive effects in the formalin test
Q38227730ITH12410/SC058: a new neuroprotective compound with potential in the treatment of Alzheimer's disease
Q60689087Identification of 4,6-diaryl-1,4-dihydropyridines as a new class of neuroprotective agents
Q39075138Ischemic brain injury: New insights on the protective role of melatonin
Q38317383Lectin from Canavalia brasiliensis (ConBr) protects hippocampal slices against glutamate neurotoxicity in a manner dependent of PI3K/Akt pathway
Q104560418Melatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux
Q38684594Melatonin as a versatile molecule to design novel multitarget hybrids against neurodegeneration
Q46490330Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices
Q42107527Melatonin-sulforaphane hybrid ITH12674 induces neuroprotection in oxidative stress conditions by a 'drug-prodrug' mechanism of action
Q46718947Microglial HO-1 induction by curcumin provides antioxidant, antineuroinflammatory, and glioprotective effects
Q42936340Mitochondrial Na+/Ca2+ exchanger, a new target for neuroprotection in rat hippocampal slices
Q45976080Mitochondrial Na+/Ca2+-exchanger blocker CGP37157 protects against chromaffin cell death elicited by veratridine.
Q60689081Modulation of serine/threonine phosphatases by melatonin: therapeutic approaches in neurodegenerative diseases
Q59505514Multipotente Liganden mit kombinierter Cholinesterase- und Monoaminooxidase-Inhibition sowie Histamin-H3 R-Antagonismus bei neurodegenerativen Erkrankungen
Q48130975Multitarget-Directed Ligands Combining Cholinesterase and Monoamine Oxidase Inhibition with Histamine H3 R Antagonism for Neurodegenerative Diseases.
Q33850729N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease
Q42503323NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.
Q46114392NP04634 prevents cell damage caused by calcium overload and mitochondrial disruption in bovine chromaffin cells
Q98164577Na+ controls hypoxic signalling by the mitochondrial respiratory chain
Q46912355Neuroprotectant minocycline depresses glutamatergic neurotransmission and Ca(2+) signalling in hippocampal neurons.
Q28591328Neuroprotection afforded by nicotine against oxygen and glucose deprivation in hippocampal slices is lost in alpha7 nicotinic receptor knockout mice
Q48326424Neuroprotection by nicotine in hippocampal slices subjected to oxygen-glucose deprivation: involvement of the alpha7 nAChR subtype
Q46922338Neuroprotective effect of dimebon against ischemic neuronal damage
Q54581993Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition.
Q39042187Neuroprotective effect of melatonin against ischemia is partially mediated by alpha-7 nicotinic receptor modulation and HO-1 overexpression
Q46601596Neuroprotective effect of the new thiadiazolidinone NP00111 against oxygen-glucose deprivation in rat hippocampal slices: implication of ERK1/2 and PPARgamma receptors
Q48329113Neuroprotective effects of E-PodoFavalin-15999 (Atremorine®).
Q38851642Neuroprotective mechanism of the novel melatonin derivative Neu-P11 in brain ischemia related models
Q39530798Neurotoxicity induced by dexamethasone in the human neuroblastoma SH-SY5Y cell line can be prevented by folic acid.
Q39515762Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by α7 and β2* nicotinic stimulation
Q44908231Neurotransmitters, calcium signalling and neuronal communication
Q39002084New 5-unsubstituted dihydropyridines with improved CaV1.3 selectivity as potential neuroprotective agents against ischemic injury
Q38950400New melatonin-cinnamate hybrids as multi-target drugs for neurodegenerative diseases: Nrf2-induction, antioxidant effect and neuroprotection.
Q58436324Nicotinic receptor activation by epibatidine induces heme oxygenase-1 and protects chromaffin cells against oxidative stress
Q38814647Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography
Q48258502Novel multitarget ligand ITH33/IQM9.21 provides neuroprotection in in vitro and in vivo models related to brain ischemia
Q48401352Novel tacrine-grafted Ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic acid hybrids
Q38652602Nrf2-ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases.
Q40061304Nrf2-mediated haeme oxygenase-1 up-regulation induced by cobalt protoporphyrin has antinociceptive effects against inflammatory pain in the formalin test in mice
Q60688901Participation of calbindin-D28K in nociception: results from calbindin-D28K knockout mice
Q47330519Podocytes are new cellular targets of haemoglobin-mediated renal damage.
Q38913180Positive allosteric modulation of alpha-7 nicotinic receptors promotes cell death by inducing Ca(2+) release from the endoplasmic reticulum
Q42874918Poststress treatment with PNU282987 can rescue SH-SY5Y cells undergoing apoptosis via α7 nicotinic receptors linked to a Jak2/Akt/HO-1 signaling pathway
Q104742929Protective Role of Nrf2 in Renal Disease
Q39181634Protective effect of creatine against 6-hydroxydopamine-induced cell death in human neuroblastoma SH-SY5Y cells: Involvement of intracellular signaling pathways.
Q64249983QuinoxalineTacrine QT78, a Cholinesterase Inhibitor as a Potential Ligand for Alzheimer's Disease Therapy
Q27000279Redox control of microglial function: molecular mechanisms and functional significance
Q51552162Regulation by L channels of Ca(2+)-evoked secretory responses in ouabain-treated chromaffin cells.
Q42126283Sensory Input-Dependent Changes in Glutamatergic Neurotransmission- Related Genes and Proteins in the Adult Rat Trigeminal Ganglion
Q92947743Serum Amyloid A1 as a Potential Intracranial and Extracranial Clinical Severity Biomarker in Traumatic Brain Injury
Q46937770Small synthetic hyaluronan disaccharides afford neuroprotection in brain ischemia-related models
Q48125798Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures
Q39694999Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells
Q58010802Synthesis and biological assessment of diversely substituted furo[2,3-b]quinolin-4-amine and pyrrolo[2,3-b]quinolin-4-amine derivatives, as novel tacrine analogues
Q39688701Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives
Q39299148Targeting Nrf2 in the Protection against Renal Disease.
Q48950857The Antioxidant Additive Approach for Alzheimer's Disease Therapy: New Ferulic (Lipoic) Acid Plus Melatonin Modified Tacrines as Cholinesterases Inhibitors, Direct Antioxidants, and Nuclear Factor (Erythroid-Derived 2)-Like 2 Activators
Q46120469The N-terminal tripeptide of insulin-like growth factor-I protects against beta-amyloid-induced somatostatin depletion by calcium and glycogen synthase kinase 3 beta modulation.
Q54656497The antinociceptive effects of AR-A014418, a selective inhibitor of glycogen synthase kinase-3 beta, in mice.
Q38940729The melatonin-N,N-dibenzyl(N-methyl)amine hybrid ITH91/IQM157 affords neuroprotection in an in vitro Alzheimer's model via hemo-oxygenase-1 induction
Q42964845The microglial α7-acetylcholine nicotinic receptor is a key element in promoting neuroprotection by inducing heme oxygenase-1 via nuclear factor erythroid-2-related factor 2.

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