CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes

scientific article published on May 2017

CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CCELL.2017.04.005
P932PMC publication ID5587180
P698PubMed publication ID28486105

P50authorStephen B. BaylinQ28113000
Wenbing XieQ41634154
P2093author name stringMichael M Seidman
Feyruz V Rassool
Li-Rong Yu
Daiming Fan
Yi Cai
Huili Li
Kaichun Wu
Yongzhan Nie
Cynthia A Zahnow
Limin Xia
Wenjie Huang
Ray-Whay Chiu Yen
Yang W Zhang
Wenbing Xie
Marina Bellani
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ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaksQ24321489
XRCC3 promotes homology-directed repair of DNA damage in mammalian cellsQ24597771
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A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencingQ33268624
Comparing the DNA hypermethylome with gene mutations in human colorectal cancerQ33300134
The Mi-2/NuRD complex associates with pericentromeric heterochromatin during S phase in rapidly proliferating lymphoid cellsQ33601155
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damageQ33715275
The chromatin-remodeling factor CHD4 coordinates signaling and repair after DNA damageQ34110993
Cancer biology and NuRD: a multifaceted chromatin remodelling complexQ34148512
Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage.Q34485631
Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.Q34981653
Resistance to therapy in BRCA2 mutant cells due to loss of the nucleosome remodeling factor CHD4.Q35173275
The TWIST/Mi2/NuRD protein complex and its essential role in cancer metastasisQ35348193
Chromodomain helicase DNA-binding protein 4 (CHD4) regulates homologous recombination DNA repair, and its deficiency sensitizes cells to poly(ADP-ribose) polymerase (PARP) inhibitor treatment.Q35838961
A DNA hypermethylation module for the stem/progenitor cell signature of cancer.Q35914847
The chromatin remodeling complex NuRD establishes the poised state of rRNA genes characterized by bivalent histone modifications and altered nucleosome positionsQ35991515
Depletion of the chromatin remodeler CHD4 sensitizes AML blasts to genotoxic agents and reduces tumor formationQ36070463
Replication fork stability confers chemoresistance in BRCA-deficient cellsQ36083474
Genome-wide nucleosome specificity and function of chromatin remodellers in ES cellsQ36912132
The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genesQ37445834
Colorectal cancer epigenetics: complex simplicityQ37827277
H3K9 methyltransferase G9a and the related molecule GLP.Q37865974
Interplay between the cancer genome and epigenomeQ38094260
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Defeating EpCAM(+) liver cancer stem cells by targeting chromatin remodeling enzyme CHD4 in human hepatocellular carcinomaQ38861692
A model for transmission of the H3K27me3 epigenetic markQ39927750
Targeted p16(Ink4a) epimutation causes tumorigenesis and reduces survival in mice.Q42252961
Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress.Q50942636
Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4aQ57277034
Crosstalk between chromatin state and DNA damage response in cellular senescence and cancerQ95407636
P4510describes a project that usesImageJQ1659584
P433issue5
P304page(s)653-668.e7
P577publication date2017-05-01
P1433published inCancer CellQ280018
P1476titleCHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes
P478volume31

Reverse relations

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