| scholarly article | Q13442814 |
| P50 | author | Mark Marsh | Q37383678 |
| P2093 | author name string | Griffiths G | |
| Pelchen-Matthews A | |||
| Armes JE | |||
| P2860 | cites work | Five epitopes of a differentiation antigen on human inducer T cells distinguished by monoclonal antibodies | Q72708729 |
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| Interaction between CD4 and class II MHC molecules mediates cell adhesion | Q24339626 | ||
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| On the entry of Semliki forest virus into BHK-21 cells | Q27482326 | ||
| Human immunodeficiency virus infection of T cells and monocytes proceeds via receptor-mediated endocytosis | Q27482398 | ||
| HIV-gp120 can block CD4-class II MHC-mediated adhesion | Q28254561 | ||
| Lymphocyte activation by HIV-1 envelope glycoprotein | Q28281341 | ||
| The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck | Q28506433 | ||
| The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain | Q29618472 | ||
| Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts | Q33396990 | ||
| Binding site for human immunodeficiency virus coat protein gp120 is located in the NH2-terminal region of T4 (CD4) and requires the intact variable-region-like domain | Q33641132 | ||
| Transferrin receptor and its recycling in HeLa cells | Q33927904 | ||
| Interaction of the unique N-terminal region of tyrosine kinase p56lck with cytoplasmic domains of CD4 and CD8 is mediated by cysteine motifs | Q34149224 | ||
| The structure of the CD4 and CD8 genes | Q34685548 | ||
| Surface redistribution of 125I-insulin in cultured human lymphocytes | Q36205471 | ||
| Exocytosis of pinocytosed fluid in cultured cells: kinetic evidence for rapid turnover and compartmentation | Q36208793 | ||
| Phorbol esters and horseradish peroxidase stimulate pinocytosis and redirect the flow of pinocytosed fluid in macrophages | Q36211893 | ||
| Rapid analytical and preparative isolation of functional endosomes by free flow electrophoresis | Q36215953 | ||
| A quantitative analysis of the endocytic pathway in baby hamster kidney cells | Q36222043 | ||
| Meeting of the apical and basolateral endocytic pathways of the Madin-Darby canine kidney cell in late endosomes. | Q36222258 | ||
| Role of the human transferrin receptor cytoplasmic domain in endocytosis: localization of a specific signal sequence for internalization | Q36222540 | ||
| Perturbation of the T4 molecule transmits a negative signal to T cells | Q36350963 | ||
| Endocytosis and recycling of the T3-T cell receptor complex. The role of T3 phosphorylation | Q36353522 | ||
| Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes | Q36354762 | ||
| Coated pits act as molecular filters | Q36398255 | ||
| CD4: collaborator in immune recognition and HIV infection | Q37808725 | ||
| Virus entry into animal cells | Q38226881 | ||
| The lck tyrosine protein kinase interacts with the cytoplasmic tail of the CD4 glycoprotein through its unique amino-terminal domain | Q38343044 | ||
| The CD4 antigen: physiological ligand and HIV receptor | Q39184539 | ||
| Receptor-mediated endocytosis: concepts emerging from the LDL receptor system | Q39461911 | ||
| Continuous growth and differentiation of human myeloid leukaemic cells in suspension culture | Q40512568 | ||
| Human immunodeficiency virus infection of CD4-bearing cells occurs by a pH-independent mechanism | Q41091293 | ||
| The dynamic nature of the Golgi complex | Q41569694 | ||
| Characterization of the cation-independent mannose 6-phosphate receptor-enriched prelysosomal compartment in NRK cells | Q41635815 | ||
| Endocytosis and recycling of CD4. | Q41737817 | ||
| pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane | Q41764642 | ||
| Monoclonal antibody and enzymatic profiles of human malignant T-lymphoid cells and derived cell lines. | Q42822797 | ||
| Induction of HTLV-III/LAV from a nonvirus-producing T-cell line: implications for latency | Q44325918 | ||
| Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4. | Q44534068 | ||
| Role of the L3T4-antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cells | Q44844175 | ||
| Human T lymphocytes and monocytes bear the same Leu-3(T4) antigen | Q44886750 | ||
| HIV infection does not require endocytosis of its receptor, CD4. | Q45149382 | ||
| Adsorptive endocytosis of Semliki Forest virus | Q45790815 | ||
| The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family | Q48376775 | ||
| Comodulation of CD3 and CD4. Evidence for a specific association between CD4 and approximately 5% of the CD3:T cell receptor complexes on helper T lymphocytes. | Q50897238 | ||
| Fc receptor isoforms exhibit distinct abilities for coated pit localization as a result of cytoplasmic domain heterogeneity. | Q52486393 | ||
| CONTINUOUS CULTURE OF HUMAN LYMPHOBLASTS FROM PERIPHERAL BLOOD OF A CHILD WITH ACUTE LEUKEMIA. | Q52828546 | ||
| T4 endocytosis and phosphorylation induced by phorbol esters but not by mitogen or HIV infection. | Q54389507 | ||
| Transient modulation and internalization of T4 antigen induced by phorbol esters. | Q54424003 | ||
| Evidence for a physical association of CD4 and the CD3: α : β T-cell receptor | Q58974599 | ||
| A method using 3-O-methyl-D-glucose and phloretin for the determination of intracellular water space of cells in monolayer culture | Q67347702 | ||
| Internalization and cycling of the T cell antigen receptor. Role of protein kinase C | Q68829352 | ||
| The role of L3T4 in T cell activation: L3T4 may be both an Ia-binding protein and a receptor that transduces a negative signal | Q68856856 | ||
| Synergism between HIV gp120 and gp120-specific antibody in blocking human T cell activation | Q69374141 | ||
| Activators of protein kinase C induce dissociation of CD4, but not CD8, from p56lck | Q69742196 | ||
| Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen | Q70017245 | ||
| Signal transduction through CD4 receptors: stimulatory vs. inhibitory activity is regulated by CD4 proximity to the CD3/T cell receptor | Q70053370 | ||
| Cross-linking of the T cell receptor complex with the subset-specific differentiation antigen stimulates interleukin 2 receptor expression in human CD4 and CD8 T cells | Q70336391 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | lymphocyte | Q715347 |
| P304 | page(s) | 575-587 | |
| P577 | publication date | 1991-03-01 | |
| P1433 | published in | Journal of Experimental Medicine | Q3186912 |
| P1476 | title | Differential endocytosis of CD4 in lymphocytic and nonlymphocytic cells | |
| P478 | volume | 173 |
| Q28612864 | A Role for Acidic Residues in Di-leucine Motif-based Targeting to the Endocytic Pathway |
| Q24681865 | A conserved dileucine motif mediates clathrin and AP-2-dependent endocytosis of the HIV-1 envelope protein |
| Q41594028 | A lymphocyte-specific protein tyrosine kinase, p56lck, regulates the PMA-induced internalization of CD4 |
| Q37697278 | A novel endocytosis signal related to the KKXX ER-retrieval signal |
| Q36236526 | An internalization signal in the simian immunodeficiency virus transmembrane protein cytoplasmic domain modulates expression of envelope glycoproteins on the cell surface |
| Q41101974 | Antigen endocytosis and presentation mediated by human membrane IgG1 in the absence of the Ig(alpha)/Ig(beta) dimer |
| Q93037403 | Application of Physiologically Based Pharmacokinetic Modeling to Predict the Effects of FcRn Inhibitors in Mice, Rats, and Monkeys |
| Q33717239 | Aptamer-targeted cell-specific RNA interference |
| Q35991137 | CD4 Receptor is a Key Determinant of Divergent HIV-1 Sensing by Plasmacytoid Dendritic Cells. |
| Q40478558 | CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms. |
| Q35769448 | CD4/CD8 coreceptors in thymocyte development, selection, and lineage commitment: analysis of the CD4/CD8 lineage decision |
| Q33784814 | Carboxypeptidase D (gp180), a Golgi-resident protein, functions in the attachment and entry of avian hepatitis B viruses |
| Q36236078 | Clathrin-independent pinocytosis is induced in cells overexpressing a temperature-sensitive mutant of dynamin |
| Q36845470 | Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation |
| Q38070788 | Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium |
| Q30436655 | Controllable self-assembly of nanoparticles for specific delivery of multiple therapeutic molecules to cancer cells using RNA nanotechnology |
| Q36365202 | Current progress of RNA aptamer-based therapeutics |
| Q36941351 | Di-leucine signals mediate targeting of tyrosinase and synaptotagmin to synaptic-like microvesicles within PC12 cells. |
| Q35973681 | Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors |
| Q34110093 | Differential subcellular localization of the regulatory T-cell protein LAG-3 and the coreceptor CD4. |
| Q37154861 | Disruption of the CD4-p56lck complex is required for rapid internalization of CD4 |
| Q41508053 | Down-modulation of CD4 antigen during programmed cell death in U937 cells |
| Q41518173 | Endocytosis of glycophospholipid-anchored and transmembrane forms of CD4 by different endocytic pathways |
| Q40776242 | Evidence for cell surface association between CXCR4 and ganglioside GM3 after gp120 binding in SupT1 lymphoblastoid cells |
| Q34728079 | Genome-wide shRNA screening identifies host factors involved in early endocytic events for HIV-1-induced CD4 down-regulation |
| Q40283606 | HIV infection is influenced by dynamin at 3 independent points in the viral life cycle. |
| Q41142044 | HIV1 Nef: the Machiavelli of cellular activation |
| Q38782237 | Human immune cell targeting of protein nanoparticles--caveospheres. |
| Q33930465 | Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabeta |
| Q39868503 | Human immunodeficiency virus type 1 Nef induces accumulation of CD4 in early endosomes |
| Q36625495 | Human immunodeficiency virus type 1 Nef-induced down-modulation of CD4 is due to rapid internalization and degradation of surface CD4. |
| Q36499676 | Human immunodeficiency virus type 1 Nef: adapting to intracellular trafficking pathways |
| Q40567149 | Human immunodeficiency virus type 1-associated CD4 downmodulation. |
| Q30822437 | Immunoelectron microscopic investigations of patching, capping, endocytotic and shedding processes in T and B lymphocytes |
| Q40990044 | Lack of p56lck expression correlates with CD4 endocytosis in primary lymphoid and myeloid cells |
| Q42246262 | Low level of Lck kinase in Th2 cells limits expression of CD4 co-receptor and S73 phosphorylation of transcription factor c-Jun |
| Q24533226 | Mechanism of Nef-induced CD4 endocytosis: Nef connects CD4 with the mu chain of adaptor complexes |
| Q41578766 | Mechanism of action of the monosialoganglioside GM1 as a modulator of CD4 expression. Evidence that GM1-CD4 interaction triggers dissociation of p56lck from CD4, and CD4 internalization and degradation |
| Q40509085 | Mechanisms of HIV receptor and co-receptor down-regulation by prostratin: role of conventional and novel PKC isoforms |
| Q41271185 | Modulation of CD4 lateral mobility in intact cells by an intracellularly applied antibody |
| Q24336240 | Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain |
| Q30175880 | Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal alpha helix and proline repeat of Nef selectively regulate MHC-I trafficking |
| Q24678715 | Nef-mediated clathrin-coated pit formation |
| Q67903120 | Opposing effects of protein tyrosine kinase inhibitors on the monoclonal antibody induced internalization of CD3 and CD4 antigens |
| Q46188788 | Pharmacokinetics and pharmacodynamics of CD4-anchoring bi-functional fusion inhibitor in monkeys |
| Q54096893 | Phorbol ester-induced disruption of the CD4-Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms. |
| Q35847790 | Phorbol ester-induced down modulation of tailless CD4 receptors requires prior binding of gp120 and suggests a role for accessory molecules. |
| Q42805965 | Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting |
| Q36276570 | Phorbol esters and SDF-1 induce rapid endocytosis and down modulation of the chemokine receptor CXCR4. |
| Q44779448 | Physiologically-based modeling to predict the clinical behavior of monoclonal antibodies directed against lymphocyte antigens. |
| Q36655072 | Protein kinase C and NF-κB-dependent CD4 downregulation in macrophages induced by T cell-derived soluble factors: consequences for HIV-1 infection |
| Q28477747 | Proteomic-based identification of CD4-interacting proteins in human primary macrophages |
| Q24302853 | Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes |
| Q46665328 | Recombinant VSV G proteins reveal a novel raft-dependent endocytic pathway in resorbing osteoclasts |
| Q30494182 | Regulated movement of CD4 in and out of the immunological synapse |
| Q36362480 | Regulation of T cell receptor expression in immature CD4+CD8+ thymocytes by p56lck tyrosine kinase: basis for differential signaling by CD4 and CD8 in immature thymocytes expressing both coreceptor molecules |
| Q39872888 | Role of CD4 endocytosis in human immunodeficiency virus infection. |
| Q22003751 | Roles of CD4 and coreceptors in binding, endocytosis, and proteolysis of gp120 envelope glycoproteins derived from human immunodeficiency virus type 1 |
| Q64944696 | Second-Generation Histamine H1 Receptor Antagonists Suppress Delayed Rectifier K+-Channel Currents in Murine Thymocytes. |
| Q40243687 | Second-messenger regulation of receptor association with clathrin-coated pits: a novel and selective mechanism in the control of CD4 endocytosis |
| Q46415864 | Simultaneous flow cytometric analysis of IFN-γ and CD4 mRNA and protein expression kinetics in human peripheral blood mononuclear cells during activation |
| Q28582288 | The AP2 binding site of synaptotagmin 1 is not an internalization signal but a regulator of endocytosis |
| Q34418242 | The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane |
| Q33961280 | The Rous sarcoma virus Env glycoprotein contains a highly conserved motif homologous to tyrosine-based endocytosis signals and displays an unusual internalization phenotype |
| Q41907333 | The TGN38 glycoprotein contains two non-overlapping signals that mediate localization to the trans-Golgi network |
| Q36233014 | The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts |
| Q33683328 | The downregulation of CD4 and MHC-I by primate lentiviruses: a paradigm for the modulation of cell surface receptors |
| Q38762028 | The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling. |
| Q36231657 | The human immunodeficiency virus gp120 binding site on CD4: delineation by quantitative equilibrium and kinetic binding studies of mutants in conjunction with a high-resolution CD4 atomic structure |
| Q36669879 | The human immunodeficiency virus type 1 (HIV-1) CD4 receptor and its central role in promotion of HIV-1 infection. |
| Q41338308 | The multifaceted role of HIV Nef. |
| Q37450184 | The paramyxovirus simian virus 5 hemagglutinin-neuraminidase glycoprotein, but not the fusion glycoprotein, is internalized via coated pits and enters the endocytic pathway |
| Q39030295 | The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4. |
| Q41632663 | The protein tyrosine kinase p56lck inhibits CD4 endocytosis by preventing entry of CD4 into coated pits |
| Q45738527 | The simian immunodeficiency virus envelope glycoprotein contains multiple signals that regulate its cell surface expression and endocytosis |
| Q36342168 | Trafficking of an acylated cytosolic protein: newly synthesized p56(lck) travels to the plasma membrane via the exocytic pathway |
| Q34536198 | sCD44 internalization in human trabecular meshwork cells |
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