| scholarly article | Q13442814 |
| P2093 | author name string | David H Gutmann | |
| Marco Giovannini | |||
| Ryan J Emnett | |||
| S Sean Houshmandi | |||
| P2860 | cites work | ErbB-2 activates Stat3 alpha in a Src- and JAK2-dependent manner | Q24293488 |
| Tumorigenic transformation by CPI-17 through inhibition of a merlin phosphatase | Q24298753 | ||
| Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2 | Q24313491 | ||
| Neurofibromatosis 2 (NF2) tumor suppressor schwannomin and its interacting protein HRS regulate STAT signaling | Q24319849 | ||
| Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer | Q27824847 | ||
| Protein 4.1 tumor suppressors: getting a FERM grip on growth regulation | Q28204748 | ||
| Src kinase regulation by phosphorylation and dephosphorylation | Q28246342 | ||
| The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44 | Q28363493 | ||
| Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2. | Q28507503 | ||
| Loss of tuberous sclerosis complex 1 (Tsc1) expression results in increased Rheb/S6K pathway signaling important for astrocyte cell size regulation | Q28507521 | ||
| Glioma formation in neurofibromatosis 1 reflects preferential activation of K-RAS in astrocytes | Q28510368 | ||
| NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions | Q28511556 | ||
| Merlin, the neurofibromatosis type 2 gene product, and beta1 integrin associate in isolated and differentiating Schwann cells | Q28583992 | ||
| Merlin inhibits growth hormone-regulated Raf-ERKs pathways by binding to Grb2 protein | Q28587255 | ||
| Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein. | Q28648056 | ||
| Cellular functions regulated by Src family kinases | Q29616038 | ||
| Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer | Q29616112 | ||
| Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck- and FynT-dependent T cell activation | Q29617586 | ||
| ERM proteins and merlin: integrators at the cell cortex | Q29619893 | ||
| An EGF receptor/Ral-GTPase signaling cascade regulates c-Src activity and substrate specificity | Q30449907 | ||
| Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas | Q30502716 | ||
| CD44 mediates constitutive type I receptor signaling in cervical carcinoma cells | Q31018670 | ||
| Echistatin inhibits pp125FAK autophosphorylation, paxillin phosphorylation and pp125FAK-paxillin interaction in fibronectin-adherent melanoma cells | Q33289370 | ||
| Ganglioside GD3 promotes cell growth and invasion through p130Cas and paxillin in malignant melanoma cells. | Q33904439 | ||
| ERM proteins: from cellular architecture to cell signaling | Q34079082 | ||
| Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins | Q34334946 | ||
| Astrocyte-specific inactivation of the neurofibromatosis 1 gene (NF1) is insufficient for astrocytoma formation. | Q34441257 | ||
| Neurofibromatosis 2 tumor suppressor protein colocalizes with ezrin and CD44 and associates with actin-containing cytoskeleton. | Q34447308 | ||
| Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells | Q34460378 | ||
| Focal adhesion kinase controls cellular levels of p27/Kip1 and p21/Cip1 through Skp2-dependent and -independent mechanisms. | Q34717950 | ||
| Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouse | Q35776239 | ||
| Contact-dependent inhibition of EGFR signaling by Nf2/Merlin | Q36118464 | ||
| New concepts regarding focal adhesion kinase promotion of cell migration and proliferation | Q36528648 | ||
| Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation | Q37383632 | ||
| Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L | Q37709703 | ||
| An anti-Ras function of neurofibromatosis type 2 gene product (NF2/Merlin). | Q38304298 | ||
| Epidermal growth factor stimulates Rac activation through Src and phosphatidylinositol 3-kinase to promote colonic epithelial cell migration | Q40054538 | ||
| Dasatinib, an orally active small molecule inhibitor of both the src and abl kinases, selectively inhibits growth of basal-type/"triple-negative" breast cancer cell lines growing in vitro | Q40176252 | ||
| Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac. | Q40181731 | ||
| Inhibition of the hyaluronan-CD44 interaction by merlin contributes to the tumor-suppressor activity of merlin | Q40235602 | ||
| Involvement of the paxillin pathway in JB6 Cl41 cell transformation | Q40272691 | ||
| Re-expression of the tumor suppressor NF2/merlin inhibits invasiveness in mesothelioma cells and negatively regulates FAK. | Q40284714 | ||
| The c-Src tyrosine kinase associates with the catalytic domain of ErbB-2: implications for ErbB-2 mediated signaling and transformation. | Q40371716 | ||
| p27Kip1 and cyclin D1 are necessary for focal adhesion kinase regulation of cell cycle progression in glioblastoma cells propagated in vitro and in vivo in the scid mouse brain | Q40489224 | ||
| Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells | Q40568614 | ||
| Lentivirus-delivered stable gene silencing by RNAi in primary cells | Q41996459 | ||
| Formation of a beta1 integrin signaling complex in Schwann cells is independent of rho. | Q42528418 | ||
| The Nf2 tumor suppressor, merlin, functions in Rac-dependent signaling. | Q42823880 | ||
| The neurofibromatosis type 2 gene is inactivated in schwannomas | Q43555539 | ||
| Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology | Q44064233 | ||
| Discovery of N-(2-chloro-6-methyl- phenyl)-2-(6-(4-(2-hydroxyethyl)- piperazin-1-yl)-2-methylpyrimidin-4- ylamino)thiazole-5-carboxamide (BMS-354825), a dual Src/Abl kinase inhibitor with potent antitumor activity in preclinical assays. | Q45198729 | ||
| Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity. | Q48106714 | ||
| A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor | Q48129277 | ||
| Nucleophosmin mediates mammalian target of rapamycin-dependent actin cytoskeleton dynamics and proliferation in neurofibromin-deficient astrocytes | Q48164011 | ||
| Tumor suppressor in lung cancer-1 (TSLC1) functions as a glioma tumor suppressor | Q48356306 | ||
| Defects in neurofibromatosis 2 protein function can arise at multiple levels. | Q48489922 | ||
| Protein 4.1B/differentially expressed in adenocarcinoma of the lung-1 functions as a growth suppressor in meningioma cells by activating Rac1-dependent c-Jun-NH(2)-kinase signaling. | Q48535606 | ||
| Loss of merlin expression in sporadic meningiomas, ependymomas and schwannomas | Q48672251 | ||
| Expression of the neurofibromatosis 2 tumor suppressor gene product, merlin, in Schwann cells. | Q52198858 | ||
| Eleven novel mutations in the NF2 tumour suppressor gene | Q57266930 | ||
| Predominant occurrence of somatic mutations of theNF2 gene in meningiomas and schwannomas | Q57304749 | ||
| Evidence for the complete inactivation of the NF2 gene in the majority of sporadic meningiomas | Q58862180 | ||
| Direct and specific interaction of c-Src with Neu is involved in signaling by the epidermal growth factor receptor | Q71703153 | ||
| C-Src activation by ErbB2 leads to attachment-independent growth of human breast epithelial cells | Q77293332 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | cell growth | Q189159 |
| neurofibromatosis type II | Q1935832 | ||
| P304 | page(s) | 1472-1486 | |
| P577 | publication date | 2008-12-22 | |
| P1433 | published in | Molecular and Cellular Biology | Q3319478 |
| P1476 | title | The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner | |
| P478 | volume | 29 |
| Q58543600 | A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas |
| Q30464280 | Contribution of persistent C-Jun N-terminal kinase activity to the survival of human vestibular schwannoma cells by suppression of accumulation of mitochondrial superoxides. |
| Q54282272 | DNA copy gains of tumor-related genes in vestibular schwannoma. |
| Q50973584 | E-cadherin expression is correlated with focal adhesion kinase inhibitor resistance in Merlin-negative malignant mesothelioma cells. |
| Q37885731 | Emerging therapeutic targets in schwannomas and other merlin-deficient tumors |
| Q54867398 | Hallmarks of glioblastoma: a systematic review. |
| Q42493873 | Insulin-like growth factor-binding protein-1 (IGFBP-1) regulates human schwannoma proliferation, adhesion and survival. |
| Q39212723 | Involvement of Src in the membrane skeletal complex, MPP6-4.1G, in Schmidt-Lanterman incisures of mouse myelinated nerve fibers in PNS. |
| Q34193347 | Merlin deficiency predicts FAK inhibitor sensitivity: a synthetic lethal relationship |
| Q34389516 | Merlin is a negative regulator of human melanoma growth |
| Q28283076 | Merlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survival |
| Q38010858 | Merlin, a multi-suppressor from cell membrane to the nucleus |
| Q35670477 | Merlin-deficient human tumors show loss of contact inhibition and activation of Wnt/β-catenin signaling linked to the PDGFR/Src and Rac/PAK pathways |
| Q30456266 | Microarray analysis of gene expression in vestibular schwannomas reveals SPP1/MET signaling pathway and androgen receptor deregulation |
| Q36273267 | NF2 Loss Promotes Oncogenic RAS-Induced Thyroid Cancers via YAP-Dependent Transactivation of RAS Proteins and Sensitizes Them to MEK Inhibition |
| Q30440530 | NF2/merlin in hereditary neurofibromatosis 2 versus cancer: biologic mechanisms and clinical associations |
| Q64102900 | Neurofibromatosis type 2 gene mutation and progesterone receptor messenger RNA expression in the pathogenesis of sporadic orbitocranial meningioma |
| Q26825296 | Neurofibromatosis type 2 protein, NF2: an uncoventional cell cycle regulator |
| Q55234046 | Neurofibromatosis type 2 tumor suppressor protein is expressed in oligodendrocytes and regulates cell proliferation and process formation. |
| Q30459213 | Neurofibromatosis type 2 tumor suppressor protein, NF2, induces proteasome-mediated degradation of JC virus T-antigen in human glioblastoma |
| Q37643115 | Neurooncology of familial cancer syndromes |
| Q24307540 | Nf2-Yap signaling controls the expansion of DRG progenitors and glia during DRG development |
| Q33591646 | Nf2/Merlin controls spinal cord neural progenitor function in a Rac1/ErbB2-dependent manner |
| Q30398838 | Oncogenic role of Merlin/NF2 in glioblastoma |
| Q30438898 | Optimizing biologically targeted clinical trials for neurofibromatosis. |
| Q92572049 | Peroxynitrite supports a metabolic reprogramming in merlin-deficient Schwann cells and promotes cell survival |
| Q84990314 | Podoplanin and CD34 in peripheral nerve sheath tumours: focus on neurofibromatosis 1-associated atypical neurofibroma |
| Q42223215 | Ponatinib promotes a G1 cell-cycle arrest of merlin/NF2-deficient human schwann cells |
| Q90250769 | Proximity biotinylation identifies a set of conformation-specific interactions between Merlin and cell junction proteins |
| Q38979328 | Regulation of Drosophila glial cell proliferation by Merlin-Hippo signaling |
| Q36189820 | Role of Merlin/NF2 inactivation in tumor biology |
| Q38180808 | Schwannomas and their pathogenesis |
| Q39904260 | The neurofibromatosis type 1 tumor suppressor controls cell growth by regulating signal transducer and activator of transcription-3 activity in vitro and in vivo. |
| Q34999204 | The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. |
| Q28590774 | The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens |
| Q28504464 | Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators |
| Q34176631 | Using the neurofibromatosis tumor predisposition syndromes to understand normal nervous system development |
| Q39173616 | Vascular hyperpermeability as a hallmark of phacomatoses: is the etiology angiogenesis related to or comparable with mechanisms seen in inflammatory pathways? Part II: angiogenesis- and inflammation-related molecular pathways, tumor-associated macro |
| Q91823921 | YAP/TAZ Inhibition Induces Metabolic and Signaling Rewiring Resulting in Targetable Vulnerabilities in NF2-Deficient Tumor Cells |
| Q30401833 | p75NTR is highly expressed in vestibular schwannomas and promotes cell survival by activating nuclear transcription factor κB. |
Search more.