An anti-Ras function of neurofibromatosis type 2 gene product (NF2/Merlin).

scientific article published on September 1994

An anti-Ras function of neurofibromatosis type 2 gene product (NF2/Merlin). is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID8089100

P2093author name stringTikoo A
Ramesh V
Varga M
Gusella J
Maruta H
P433issue38
P407language of work or nameEnglishQ1860
P921main subjectneurofibromatosis type IIQ1935832
P304page(s)23387-23390
P577publication date1994-09-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleAn anti-Ras function of neurofibromatosis type 2 gene product (NF2/Merlin)
P478volume269

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cites work (P2860)
Q24533435Binding of the merlin-I product of the neurofibromatosis type 2 tumour suppressor gene to a novel site in beta-fodrin is regulated by association between merlin domains
Q22253159Cloning and characterization of SCHIP-1, a novel protein interacting specifically with spliced isoforms and naturally occurring mutant NF2 proteins
Q92637203Contribution of mTOR and PTEN to Radioresistance in Sporadic and NF2-Associated Vestibular Schwannomas: A Microarray and Pathway Analysis
Q41834097Distinct overlapping sequences at the carboxy-terminus of merlin regulate its tumour suppressor and morphogenic activity
Q42827339Ezrin expression in stromal cells of capillary hemangioblastoma. An immunohistochemical survey of brain tumors.
Q40370592Ezrin function is required for ROCK-mediated fibroblast transformation by the Net and Dbl oncogenes
Q24617964Ezrin self-association involves binding of an N-terminal domain to a normally masked C-terminal domain that includes the F-actin binding site
Q34145489Functional analysis of the neurofibromatosis type 2 protein by means of disease-causing point mutations
Q24338893Identification and characterization of putative tumor suppressor NGB, a GTP-binding protein that interacts with the neurofibromatosis 2 protein
Q30495325Identification of recurrent regions of chromosome loss and gain in vestibular schwannomas using comparative genomic hybridisation
Q24648337Increased expression of the Ras suppressor Rsu-1 enhances Erk-2 activation and inhibits Jun kinase activation
Q35049697Inhibition of Cdc42-mediated activation of mixed lineage kinase 3 by the tumor suppressor protein merlin
Q28283076Merlin, a "magic" linker between extracellular cues and intracellular signaling pathways that regulate cell motility, proliferation, and survival
Q38105985Merlin, the NF2 Gene Product
Q38023101Merlin: The wizard requires protein stability to function as a tumor suppressor
Q30457681Molecular mechanisms promoting the pathogenesis of Schwann cell neoplasms
Q47212698Mutual regulation of the Hippo/Wnt/LPA/TGF‑β signaling pathways and their roles in glaucoma (Review).
Q30498854Neurofibromatosis type 2 protein co-localizes with elements of the cytoskeleton
Q26825296Neurofibromatosis type 2 protein, NF2: an uncoventional cell cycle regulator
Q30486851Reduced expression of neurofibromin in human meningiomas
Q38979328Regulation ofDrosophilaglial cell proliferation by Merlin-Hippo signaling
Q36189820Role of Merlin/NF2 inactivation in tumor biology
Q39575140Role of phosphatidylinositol 4,5-bisphosphate in Ras/Rac-induced disruption of the cortactin-actomyosin II complex and malignant transformation.
Q71131047Screening for mutations in the neurofibromatosis type 2 (NF2) gene in sporadic meningiomas
Q34658335Silencing of CD44 Gene Expression in Human 143-B Osteosarcoma Cells Promotes Metastasis of Intratibial Tumors in SCID Mice
Q33707642The NF2 tumor suppressor gene product, merlin, inhibits cell proliferation and cell cycle progression by repressing cyclin D1 expression
Q91937389The NF2 tumor suppressor merlin interacts with Ras and RasGAP, which may modulate Ras signaling
Q41814702The neurofibromatosis 2 protein, merlin, regulates glial cell growth in an ErbB2- and Src-dependent manner
Q24650089The neurofibromatosis 2 tumor suppressor gene product, merlin, regulates human meningioma cell growth by signaling through YAP
Q54774110The phosphorylation status of merlin in sporadic vestibular Schwannomas.
Q28590774The tumor suppressor merlin is required for cell cycle exit, terminal differentiation, and cell polarity in the developing murine lens

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