| P2093 | author name string | Xiao-Fang Yu | |
| | Wei Wei | |
| | Haoran Guo | |
| | Richard Markham | |
| | Qimeng Gao | |
| P2860 | cites work | SAMHD1-deficient CD14+ cells from individuals with Aicardi-Goutières syndrome are highly susceptible to HIV-1 infection | Q21089603 |
| | T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction | Q24300389 |
| | Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolase | Q24339547 |
| | Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx protein | Q24605807 |
| | How SAMHD1 changes our view of viral restriction | Q24605899 |
| | SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx | Q24605940 |
| | SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells | Q24615124 |
| | SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates | Q24624362 |
| | Tetramerization of SAMHD1 is required for biological activity and inhibition of HIV infection | Q24634238 |
| | Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein | Q24635842 |
| | Localization of the Vpx packaging signal within the C terminus of the human immunodeficiency virus type 2 Gag precursor protein | Q24645706 |
| | Vpx is critical for reverse transcription of the human immunodeficiency virus type 2 genome in macrophages | Q24651077 |
| | MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0 | Q26778434 |
| | HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase | Q27675416 |
| | Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection | Q28472652 |
| | Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase | Q29871440 |
| | Co-evolution of primate SAMHD1 and lentivirus Vpx leads to the loss of the vpx gene in HIV-1 ancestor | Q30416610 |
| | SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells. | Q30421200 |
| | Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction | Q33331396 |
| | VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes | Q33563208 |
| | Interaction with the p6 domain of the gag precursor mediates incorporation into virions of Vpr and Vpx proteins from primate lentiviruses | Q33639651 |
| | A conserved dileucine-containing motif in p6(gag) governs the particle association of Vpx and Vpr of simian immunodeficiency viruses SIV(mac) and SIV(agm) | Q33824939 |
| | HIV/simian immunodeficiency virus (SIV) accessory virulence factor Vpx loads the host cell restriction factor SAMHD1 onto the E3 ubiquitin ligase complex CRL4DCAF1. | Q34256688 |
| | The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus | Q34299501 |
| | Contribution of SAM and HD domains to retroviral restriction mediated by human SAMHD1. | Q34312205 |
| | The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation | Q34340339 |
| | Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1. | Q34371066 |
| | Evolutionary toggling of Vpx/Vpr specificity results in divergent recognition of the restriction factor SAMHD1. | Q34845553 |
| | Identification of critical regions in human SAMHD1 required for nuclear localization and Vpx-mediated degradation | Q34846363 |
| | Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages | Q36052320 |
| | Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac | Q36136752 |
| | Functional analysis of the relationship between Vpx and the restriction factor SAMHD1. | Q36436068 |
| | SAMHD1 restricts HIV-1 infection in dendritic cells (DCs) by dNTP depletion, but its expression in DCs and primary CD4+ T-lymphocytes cannot be upregulated by interferons | Q36480173 |
| | Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis. | Q36655127 |
| | Dispensable role of the human immunodeficiency virus type 2 Vpx protein in viral replication | Q36701891 |
| | The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage | Q36797922 |
| | Restriction of virus infection but not catalytic dNTPase activity is regulated by phosphorylation of SAMHD1. | Q37252735 |
| | Evidence for an activation domain at the amino terminus of simian immunodeficiency virus Vpx. | Q38348781 |
| | Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1. | Q39163475 |
| | A novel DCAF1-binding motif required for Vpx-mediated degradation of nuclear SAMHD1 and Vpr-induced G2 arrest | Q39317549 |
| | The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx. | Q39405160 |
| | SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells | Q40185026 |
| | Intracellular transport and virion incorporation of vpx requires interaction with other virus type-specific components. | Q41570102 |
| | A naturally immunogenic virion-associated protein specific for HIV-2 and SIV. | Q42649286 |
| | Isolation and characterization of a novel protein (X-ORF product) from SIV and HIV-2. | Q42658314 |
| | High levels of transduction of human dendritic cells with optimized SIV vectors | Q43894572 |
| | Restricting HIV the SAMHD1 way: through nucleotide starvation. | Q55056626 |
| P433 | issue | 1 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 583-591 | |
| P577 | publication date | 2013-10-30 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Variation of two primate lineage-specific residues in human SAMHD1 confers resistance to N terminus-targeted SIV Vpx proteins | |
| P478 | volume | 88 | |