| scholarly article | Q13442814 |
| P2093 | author name string | B K Park | |
| M D Tingle | |||
| H J Gill | |||
| P2860 | cites work | Protein measurement with the Folin phenol reagent | Q20900776 |
| Polymerase chain reaction-directed identification, cloning, and quantification of human CYP2C18 mRNA | Q28299067 | ||
| Studies on dapsone induced haemolytic anaemia. I. Methaemoglobin production and G-6-PD activity in correlation with dapsone dosage | Q28327078 | ||
| THE CARBON MONOXIDE-BINDING PIGMENT OF LIVER MICROSOMES. I. EVIDENCE FOR ITS HEMOPROTEIN NATURE | Q29547810 | ||
| Adverse Reactions to Trimethoprim-Sulfamethoxazole in Patients with the Acquired Immunodeficiency Syndrome | Q33476530 | ||
| Adverse reactions to trimethoprim-sulfamethoxazole in hospitalized patients | Q33483246 | ||
| Bioactivation of dapsone to a cytotoxic metabolite by human hepatic microsomal enzymes | Q34397894 | ||
| Systemic glutathione deficiency in symptom-free HIV-seropositive individuals | Q34668415 | ||
| Agranulocytosis associated with malaria prophylaxis with Maloprim. | Q34991556 | ||
| Drug hypersensitivity reactions and human immunodeficiency virus disease | Q35553836 | ||
| Human cytochromes P450: problems and prospects | Q35856204 | ||
| A comparison of the effectiveness of three regimens in the prevention of Pneumocystis carinii pneumonia in human immunodeficiency virus-infected patients | Q35910981 | ||
| Drug-protein conjugation and its immunological consequences | Q37944829 | ||
| Clinical pharmacokinetics of cimetidine | Q40210044 | ||
| Adverse reactions to dapsone in persons infected with human immunodeficiency virus | Q40675902 | ||
| Utility of dapsone for prophylaxis of Pneumocystis carinii pneumonia in trimethoprim-sulfamethoxazole-intolerant, HIV-infected individuals | Q40720382 | ||
| Pharmacogenetic phenotyping and genotyping. Present status and future potential. | Q40730354 | ||
| Selective inhibitors of cytochromes P450. | Q40746860 | ||
| Evaluation of triacetyloleandomycin, alpha-naphthoflavone and diethyldithiocarbamate as selective chemical probes for inhibition of human cytochromes P450. | Q41462331 | ||
| Role of dapsone hydroxylamine in dapsone-induced hemolytic anemia. | Q42213026 | ||
| Cimetidine improves the therapeutic/toxic ratio of dapsone in patients on chronic dapsone therapy | Q42281277 | ||
| The use of cimetidine as a selective inhibitor of dapsone N-hydroxylation in man. | Q42284991 | ||
| The effect of preincubation with cimetidine on the N-hydroxylation of dapsone by human liver microsomes | Q43205011 | ||
| AIDS-related Pneumocystis carinii pneumonia successfully treated with dapsone-trimethoprim | Q43229283 | ||
| Studies of the metabolism of dapsone in man and experimental animals: formation of N-hydroxy metabolites | Q43964132 | ||
| Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture | Q67532013 | ||
| Patient treatment compliance in leprosy; a critical review | Q67894259 | ||
| Glutathione depletion in HIV-infected patients: role of cysteine deficiency and effect of oral N-acetylcysteine | Q67917319 | ||
| Differential inhibition of individual human liver cytochromes P-450 by cimetidine | Q68063454 | ||
| Human liver microsomal N-hydroxylation of dapsone by cytochrome P-4503A4 | Q68129421 | ||
| Cytochrome P-450-dependent formation of reactive oxygen radicals: isozyme-specific inhibition of P-450-mediated reduction of oxygen and carbon tetrachloride | Q68365315 | ||
| Selective inhibition of drug oxidation after simultaneous administration of two probe drugs, antipyrine and tolbutamide | Q68411894 | ||
| Metabolism of dapsone to a hydroxylamine by human neutrophils and mononuclear cells | Q70386022 | ||
| Mechanism of methemoglobin formation by diphenylsulfones. Effect of 4-amino-4'-hydroxyaminodiphenylsulfone and other p-substituted derivatives | Q70405638 | ||
| Ketoconazole and sulphaphenazole as the respective selective inhibitors of P4503A and 2C9 | Q71904700 | ||
| Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes | Q72164438 | ||
| Metabolism of procainamide to a hydroxylamine by rat and human hepatic microsomes | Q72572782 | ||
| Absence of correlations among three putative in vivo probes of human cytochrome P4503A activity in young healthy men | Q72692420 | ||
| P433 | issue | 6 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | dapsone | Q422226 |
| P304 | page(s) | 531-538 | |
| P577 | publication date | 1995-12-01 | |
| P1433 | published in | British Journal of Clinical Pharmacology | Q176044 |
| P1476 | title | N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity | |
| P478 | volume | 40 |
| Q42284131 | A convenient five-drug cocktail for the assessment of major drug metabolizing enzymes: a pilot study |
| Q44298049 | Activation of cytochrome P450 2C9-mediated metabolism: mechanistic evidence in support of kinetic observations |
| Q44963267 | Alosetron repeat dose pharmacokinetics, effects on enzyme activities, and influence of demographic factors |
| Q34985540 | An evaluation of dapsone gel 5% in the treatment of acne vulgaris |
| Q28365904 | An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A) |
| Q53446036 | Bioactivation and inactivation of aflatoxin B1 by human, mouse and rat liver preparations: effect on SCE in human mononuclear leucocytes. |
| Q84586179 | Bioactivation of benzocaine to a methaemoglobin-forming metabolite by rat and human microsomes in vitro |
| Q84586364 | Bioactivation of the cyanide antidote 4-aminopropiophenone (4-PAPP) by human and rat hepatic microsomal enzymes: effect of inhibitors |
| Q28538986 | Clinical oxidative stress during leprosy multidrug therapy: impact of dapsone oxidation |
| Q39450909 | Dapsone and azole interactions: A clinical perspective |
| Q35824695 | Dapsone therapy for malaria during pregnancy: maternal and fetal outcomes |
| Q40504499 | Dapsone-induced agranulocytosis. The role of xenobiotic-metabolizing enzymes demonstrated by a case report |
| Q51432740 | Determination of a 'GW cocktail' of cytochrome P450 probe substrates and their metabolites in plasma and urine using automated solid phase extraction and fast gradient liquid chromatography tandem mass spectrometry. |
| Q48610657 | Development of the "Inje cocktail" for high-throughput evaluation of five human cytochrome P450 isoforms in vivo |
| Q36061821 | Drug bioactivation, covalent binding to target proteins and toxicity relevance |
| Q46038612 | Effect of age and postoperative time on cytochrome p450 enzyme activity following liver transplantation. |
| Q41906399 | Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N-acetyltransferase in healthy human subjects |
| Q37409135 | Effects of genetic variation at the CYP2C19/CYP2C9 locus on pharmacokinetics of chlorcycloguanil in adult Gambians |
| Q33858325 | Effects of the antifungal agents on oxidative drug metabolism: clinical relevance |
| Q47823101 | Haematological and biochemical alterations in leprosy patients already treated with dapsone and MDT. |
| Q35149421 | How useful is the "cocktail approach" for evaluating human hepatic drug metabolizing capacity using cytochrome P450 phenotyping probes in vivo? |
| Q41172369 | Idiosyncratic drug reactions. Metabolic bioactivation as a pathogenic mechanism |
| Q43800529 | Immunohematotoxicity studies with combinations of dapsone and zidovudine |
| Q28589006 | Increased constitutive c-Jun N-terminal kinase signaling in mice lacking glutathione S-transferase Pi |
| Q44088659 | Inter-strain variability in aldehyde oxidase activity in the mouse |
| Q38694005 | Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling |
| Q36068699 | Mechanism-based inhibition of cytochrome P450 3A4 by therapeutic drugs. |
| Q43678470 | Minimal in vivo activation of CYP2C9-mediated flurbiprofen metabolism by dapsone |
| Q73045073 | Obstacles to the prediction of estrogenicity from chemical structure: assay-mediated metabolic transformation and the apparent promiscuous nature of the estrogen receptor |
| Q41371110 | Pharmacogenetics in pediatrics. Implications for practice |
| Q36964648 | Pharmacokinetic considerations in clinical toxicology: clinical applications |
| Q34296740 | Pharmacokinetic interactions of antimalarial agents |
| Q44461925 | Preclinical factors affecting the interindividual variability in the clearance of the investigational anti-cancer drug 5,6-dimethylxanthenone-4-acetic acid |
| Q40916452 | Preliminary evaluation of the toxicity and efficacy of novel 2,4-diamino-5-benzylpyrimidine-sulphone derivatives using rat and human tissues in vitro |
| Q40822890 | Preliminary in vitro toxicological evaluation of a series of 2-pyridylcarboxamidrazone candidate anti-tuberculosis compounds |
| Q53146777 | Probable warfarin and dapsone interaction. |
| Q34738805 | Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations |
| Q46711988 | Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro |
| Q40243010 | Severe dapsone hypersensitivity syndrome in a child. |
| Q62232369 | Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group |
| Q53755539 | Structure activity relationship study on the peptide hormone preptin, a novel bone-anabolic agent for the treatment of osteoporosis. |
| Q42730149 | Studies on the toxicity and efficacy of some ester analogues of dapsone in vitro using rat and human tissues |
| Q32103802 | Summary of information on human CYP enzymes: human P450 metabolism data |
| Q35583064 | Systematic review: ursodeoxycholic acid--adverse effects and drug interactions |
| Q38136748 | Systemic use of non-biologic agents in orofacial diseases: other immunomodulatory agents |
| Q47986355 | The effect of 2,2'-substitution on the metabolism and toxicity of dapsone in vitro and in vivo. |
| Q78194451 | The effect of pregnenolone 16alpha-carbonitrile on the pharmacokinetics and metabolism of dapsone in rats |
| Q36851934 | Use of in vitro and in vivo data to estimate the likelihood of metabolic pharmacokinetic interactions |
| Q73846452 | Validation of the five-drug "Pittsburgh cocktail" approach for assessment of selective regulation of drug-metabolizing enzymes |
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