Spinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat.

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Spinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JNR.21905
P932PMC publication ID2644733
P698PubMed publication ID18855936
P5875ResearchGate publication ID23317498

P50authorCamilla I SvenssonQ59689137
P2093author name stringW Marie Campana
Michael P Hefferan
Linda Sorkin
Toni L Jones-Cordero
P2860cites workTactile allodynia, but not thermal hyperalgesia, of the hindlimbs is blocked by spinal transection in rats with nerve injuryQ74328913
Activation of p38 MAP kinase in the rat dorsal root ganglia and spinal cord following peripheral inflammation and nerve injuryQ78711859
Activation of microglia and p38 mitogen-activated protein kinase in the dorsal column nucleus contributes to tactile allodynia following peripheral nerve injuryQ81162644
Tumor necrosis factor-alpha induces mechanical allodynia after spinal nerve ligation by activation of p38 MAPK in primary sensory neuronsQ28189772
P2X4 receptors induced in spinal microglia gate tactile allodynia after nerve injuryQ28201682
Quantitative assessment of tactile allodynia in the rat pawQ29617366
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesiaQ29620385
Glial activation: a driving force for pathological painQ33953790
Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesiaQ34208152
Low-dose methotrexate reduces peripheral nerve injury-evoked spinal microglial activation and neuropathic pain behavior in ratsQ36876891
The search for physiological substrates of MAP and SAP kinases in mammalian cellsQ36914508
Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthaseQ37245429
Prosaptide activates the MAPK pathway by a G-protein-dependent mechanism essential for enhanced sulfatide synthesis by Schwann cells.Q41059550
Mechanical allodynia in rats is blocked by a Ca2+ permeable AMPA receptor antagonistQ41711894
Pain models display differential sensitivity to Ca2+-permeable non-NMDA glutamate receptor antagonistsQ43769836
Pharmacology of spinal glutamatergic receptors in post-thermal injury-evoked tactile allodynia and thermal hyperalgesiaQ43901857
The selective p38 inhibitor SB-239063 protects primary neurons from mild to moderate excitotoxic injuryQ44054561
p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.Q44451943
Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate receptors mediate development, but not maintenance, of secondary allodynia evoked by first-degree burn in the rat.Q44555430
Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injuryQ44675650
Systemic administration of CNI-1493, a p38 mitogen-activated protein kinase inhibitor, blocks intrathecal human immunodeficiency virus-1 gp120-induced enhanced pain states in ratsQ45709544
A novel model of primary and secondary hyperalgesia after mild thermal injury in the rat.Q45943942
Systemic gabapentin and S(+)-3-isobutyl-gamma-aminobutyric acid block secondary hyperalgesia.Q45947870
Induction of MAPK phosphorylation by prosaposin and prosaptide in PC12 cells.Q46030974
Spinal astrocyte glutamate receptor 1 overexpression after ischemic insult facilitates behavioral signs of spasticity and rigidity.Q46061075
Activation of p38 mitogen-activated protein kinase in spinal microglia is a critical link in inflammation-induced spinal pain processingQ46165562
Pharmacological properties of SD-282 - an alpha-isoform selective inhibitor for p38 MAP kinaseQ46502298
Activated PKA and PKC, but not CaMKIIalpha, are required for AMPA/Kainate-mediated pain behavior in the thermal stimulus modelQ46693243
Chronic catheterization of the spinal subarachnoid spaceQ48344815
Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleusQ48485015
Neurogenic hyperalgesia: central neural correlates in responses of spinothalamic tract neuronsQ48694926
Nerve injury-induced tactile allodynia is mediated via ascending spinal dorsal column projections.Q51367356
Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity.Q51432094
The effect of intrathecal gabapentin and 3-isobutyl gamma-aminobutyric acid on the hyperalgesia observed after thermal injury in the rat.Q51530518
Phosphorylation of transcription factor CREB in rat spinal cord after formalin-induced hyperalgesia: relationship to c-fos induction.Q51548076
ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain modelQ57990428
Somatotopic organization of cutaneous afferent terminals and dorsal horn neuronal receptive fields in the superficial and deep laminae of the rat lumbar spinal cordQ69664700
Peripheral neural mechanisms of cutaneous hyperalgesia following mild injury by heatQ70375373
P433issue4
P304page(s)948-955
P577publication date2009-03-01
P1433published inJournal of Neuroscience ResearchQ6295654
P1476titleSpinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat.
P478volume87

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cites work (P2860)
Q34161669A p38 mitogen-activated protein kinase-dependent mechanism of disinhibition in spinal synaptic transmission induced by tumor necrosis factor-alpha
Q35159237Effect of Electroacupuncture on Activation of p38MAPK in Spinal Dorsal Horn in Rats with Complete Freund's Adjuvant-Induced Inflammatory Pain.
Q47724911Electroacupuncture attenuates spinal nerve ligation-induced microglial activation mediated by p38 mitogen-activated protein kinase
Q34039604Expression profiling of genes modulated by minocycline in a rat model of neuropathic pain
Q39248070Immunofluorescent spectral analysis reveals the intrathecal cannabinoid agonist, AM1241, produces spinal anti-inflammatory cytokine responses in neuropathic rats exhibiting relief from allodynia
Q92485986Inflammatory mediators of opioid tolerance: Implications for dependency and addiction
Q36942588Intrathecal Injection of Resveratrol Attenuates Burn Injury Pain by Activating Spinal Sirtuin 1
Q92442159Microglial Modulation as a Target for Chronic Pain: From the Bench to the Bedside and Back
Q48613201Minocycline and fluorocitrate suppress spinal nociceptive signaling in intrathecal IL-1β-induced thermal hyperalgesic rats
Q33814688Peripheral inflammation induces tumor necrosis factor dependent AMPA receptor trafficking and Akt phosphorylation in spinal cord in addition to pain behavior
Q35676163The pathophysiology of acute pain: animal models
Q40993825Transcriptomic and behavioural characterisation of a mouse model of burn pain identify the cholecystokinin 2 receptor as an analgesic target
Q92897331Yoga: Can it be integrated with treatment of neuropathic pain?

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