Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase

scientific article published on April 2008

Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.EJPHAR.2008.03.033
P932PMC publication ID2703817
P698PubMed publication ID18440503
P5875ResearchGate publication ID5410897

P2093author name stringLinda S Sorkin
Carmen M Doom
Danielle B Nanigian
Karly P Maruyama
P2860cites workNonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysisQ24646764
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Evoked Release of Amino Acids and Prostanoids in Spinal Cords of Anesthetized Rats: Changes During Peripheral Inflammation and HyperalgesiaQ34115711
The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammationQ41102806
Mechanical allodynia in rats is blocked by a Ca2+ permeable AMPA receptor antagonistQ41711894
Regulation of peripheral inflammation by spinal adenosine: role of somatic afferent fibersQ42453292
Effects of intrathecal administration of nitric oxide synthase inhibitors on carrageenan-induced thermal hyperalgesiaQ43191285
Antinociceptive actions of spinal nonsteroidal anti-inflammatory agents on the formalin test in the ratQ43453302
Pain models display differential sensitivity to Ca2+-permeable non-NMDA glutamate receptor antagonistsQ43769836
Pharmacology of spinal glutamatergic receptors in post-thermal injury-evoked tactile allodynia and thermal hyperalgesiaQ43901857
Spinal and peripheral mu opioids and the development of secondary tactile allodynia after thermal injuryQ43935278
The novel N-type calcium channel blocker, AM336, produces potent dose-dependent antinociception after intrathecal dosing in rats and inhibits substance P release in rat spinal cord slicesQ43946700
Cyclooxygenase-1 in the spinal cord plays an important role in postoperative painQ44509506
Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid/kainate receptors mediate development, but not maintenance, of secondary allodynia evoked by first-degree burn in the rat.Q44555430
Spinal glutamate receptor antagonists differentiate primary and secondary mechanical hyperalgesia caused by incision.Q44589936
Cyclooxygenase inhibition and the spinal release of prostaglandin E2 and amino acids evoked by paw formalin injection: a microdialysis study in unanesthetized rats.Q44603003
Inhibition of Spinal Prostaglandin Synthesis Early after L5/L6 Nerve Ligation Prevents the Development of Prostaglandin-dependent and Prostaglandin-independent Allodynia in the RatQ44630658
Pre- and postsynaptic contributions of voltage-dependent Ca2+ channels to nociceptive transmission in rat spinal lamina I neuronsQ44747851
Constitutive spinal cyclooxygenase-2 participates in the initiation of tissue injury-induced hyperalgesia.Q44804055
The potent inducible nitric oxide synthase inhibitor ONO-1714 inhibits neuronal NOS and exerts antinociception in ratsQ44971795
Role of voltage-dependent calcium channel subtypes in experimental tactile allodynia.Q46013689
NMDA evokes an L-NAME sensitive spinal release of glutamate and citrullineQ46052832
Spinal nitric oxide synthesis inhibition blocks NMDA-induced thermal hyperalgesia and produces antinociception in the formalin test in ratsQ46176636
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibitionQ46223466
Selective N-type neuronal voltage-sensitive calcium channel blocker, SNX-111, produces spinal antinociception in rat models of acute, persistent and neuropathic pain.Q46409717
Pharmacology of the spinal action of ketorolac, morphine, ST-91, U50488H, and L-PIA on the formalin test and an isobolographic analysis of the NSAID interactionQ46484659
Activated PKA and PKC, but not CaMKIIalpha, are required for AMPA/Kainate-mediated pain behavior in the thermal stimulus modelQ46693243
An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokineQ46832694
Effect of COX-1 and COX-2 inhibition on induction and maintenance of carrageenan-evoked thermal hyperalgesia in ratsQ46835426
Switch to Ca2+-permeable AMPA and reduced NR2B NMDA receptor-mediated neurotransmission at dorsal horn nociceptive synapses during inflammatory pain in the rat.Q46885932
Chronic catheterization of the spinal subarachnoid spaceQ48344815
Depression of NMDA-receptor-mediated segmental transmission by ketamine and ketoprofen, but not L-NAME, on the in vitro neonatal rat spinal cord preparationQ48528901
The nitric oxide-cyclic GMP pathway is required for nociceptive signalling at specific loci within the somatosensory pathwayQ48955112
Intrathecal non-NMDA excitatory amino acid receptor antagonists inhibit pain behaviors in a rat model of postoperative pain.Q51527481
Lack of effect of intrathecally administered N-methyl-D-aspartate receptor antagonists in a rat model for postoperative pain.Q51531263
Nitric oxide synthase inhibitor does not reduce minimum alveolar anesthetic concentration of halothane in rats.Q51633854
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.Q51685152
The induction and maintenance of central sensitization is dependent on N -methyl-d-aspartic acid receptor activation; implications for the treatment of post-injury pain hypersensitivity statesQ52237708
Agonist- and voltage-gated calcium entry in cultured mouse spinal cord neurons under voltage clamp measured using arsenazo III.Q52255160
l-NAME, an inhibitor of nitric oxide synthase, blocks the established allodynia induced by intrathecal administration of prostaglandin E2Q60735321
The role of NMDA receptor-operated calcium channels in persistent nociception after formalin-induced tissue injuryQ67503828
Enhanced responses of spinothalamic tract neurons to excitatory amino acids accompany capsaicin-induced sensitization in the monkeyQ68071189
Synaptic strengthening through activation of Ca2+-permeable AMPA receptorsQ71133430
Immunochemical identification and subcellular distribution of the alpha 1A subunits of brain calcium channelsQ71511381
Intrathecal ketorolac tromethamine produces analgesia after chronic constriction injury of sciatic nerve in ratQ71612212
L-thiocitrulline. A stereospecific, heme-binding inhibitor of nitric-oxide synthasesQ71650774
NMDA receptor antagonists attenuate mechanical hyperalgesia in rats with unilateral inflammation of the hindpawQ72665928
Activation of spinal N-methyl-D-aspartate receptors stimulates a nitric oxide/cyclic guanosine 3,5-monophosphate/glutamate release cascade in nociceptive signalingQ73156704
Effects of intrathecal administration of ziconotide, a selective neuronal N-type calcium channel blocker, on mechanical allodynia and heat hyperalgesia in a rat model of postoperative painQ73427479
Spinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in ratsQ73863040
Intrathecally administered COX-2 but not COX-1 or COX-3 inhibitors attenuate streptozotocin-induced mechanical hyperalgesia in ratsQ79368212
L-type calcium channels and NMDA receptors: a determinant duo for short-term nociceptive plasticityQ79619271
P433issue1-3
P407language of work or nameEnglishQ1860
P921main subjectsecondary hyperalgesiaQ108802278
P304page(s)118-123
P577publication date2008-04-01
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleSecondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase
P478volume587

Reverse relations

cites work (P2860)
Q93071825Effects of Intrathecal Verapamil on Cerebral Vasospasm in Experimental Rat Study
Q37396872Intrathecal P/Q- and R-type calcium channel blockade of spinal substance P release and c-Fos expression
Q39159941Local Administration of Thiamine Ameliorates Ongoing Pain in a Rat Model of Second-Degree Burn
Q42008612Spinal p38 mitogen-activated protein kinase mediates allodynia induced by first-degree burn in the rat.

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