Spinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in rats

scientific article published on 01 January 2000

Spinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0306-4522(00)00052-X
P698PubMed publication ID10842019

P50authorZhihong ZhaoQ73863037
P2093author name stringH L Pan
S R Chen
D W Busija
J C Eisenach
P2860cites workNociceptive effects induced by intrathecal administration of prostaglandin D2, E2, or F2 alpha to conscious miceQ28334553
Quantitative assessment of tactile allodynia in the rat pawQ29617366
Characterization of inducible cyclooxygenase in rat brainQ33593129
An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the ratQ34239178
Prostanoids synthesized by cyclo-oxygenase isoforms in rat spinal cord and their contribution to the development of neuronal hyperexcitabilityQ35027006
Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and painQ35953747
Cloning two isoforms of rat cyclooxygenase: differential regulation of their expressionQ36759109
COX-2, a synaptically induced enzyme, is expressed by excitatory neurons at postsynaptic sites in rat cerebral cortexQ37691478
Multiple representations of pain in human cerebral cortexQ39171883
The Role of Prostaglandins in the Central Nervous SystemQ39246028
Chronic neuropathic pain and its control by drugsQ40910684
Prostaglandin-induced neuropeptide release from spinal cord.Q40940941
A novel long-latency response of locus coeruleus neurons to noxious stimuli: mediation by peripheral C-fibersQ41034590
Prostaglandin E2 increases calcium conductance and stimulates release of substance P in avian sensory neuronsQ42454277
Eicosanoid metabolism in cholesterol-enriched arterial smooth muscle cells. Evidence for reduced posttranscriptional processing of cyclooxygenase I and reduced cyclooxygenase II gene expression.Q42503443
Expression of a mitogen-inducible cyclooxygenase in brain neurons: regulation by synaptic activity and glucocorticoidsQ42506522
Distribution and characterization of cyclooxygenase immunoreactivity in the ovine brainQ43664339
Hyperalgesia mediated by spinal glutamate or substance P receptor blocked by spinal cyclooxygenase inhibitionQ46223466
DAMGO inhibits prostaglandin E2-induced potentiation of a TTX-resistant Na+ current in rat sensory neurons in vitroQ46606406
Lack of analgesic effect of opioids on neuropathic and idiopathic forms of painQ48097606
MK-801 blocks the development of thermal hyperalgesia in a rat model of experimental painful neuropathyQ48690138
Analysis of the effects of cyclooxygenase (COX)-1 and COX-2 in spinal nociceptive transmission using indomethacin, a non-selective COX inhibitor, and NS-398, a COX-2 selective inhibitorQ48863125
Role of nitric oxide in the development of thermal hyperesthesia induced by sciatic nerve constriction injury in the rat.Q49251978
Painful neuropathy: altered central processing maintained dynamically by peripheral inputQ51679575
A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.Q52548223
Comparison of three rodent neuropathic pain modelsQ57503443
A thalamic nucleus specific for pain and temperature sensationQ58315038
The spinal and peripheral roles of bradykinin and prostaglandins in nociceptive processing in the ratQ60679699
Synergistic antiallodynic effects of spinal morphine with ketorolac and selective COX1- and COX2-inhibitors in nerve-injured rats☆Q60690712
Up-regulation of cyclooxygenase-2 mRNA in the rat spinal cord following peripheral inflammationQ71256145
Intrathecal ketorolac tromethamine produces analgesia after chronic constriction injury of sciatic nerve in ratQ71612212
Prostacyclin enhances the evoked-release of substance P and calcitonin gene-related peptide from rat sensory neuronsQ71666735
Prostaglandin G/H Synthase-2 Is a Major Contributor of Brain Prostaglandins in the NewbornQ71823569
Pre treatment with MK-801, a non-competitive NMDA antagonist, prevents development of mechanical hyperalgesia in a rat model of chronic neuropathy, but not in a model of chronic inflammationQ72025141
Arachidonic acid and its metabolites increase Cai in cultured rat oligodendrocytesQ72961160
The potential role of spinal cord cyclooxygenase-2 in the development of Freund's complete adjuvant-induced changes in hyperalgesia and allodyniaQ73343907
Increased levels of cyclooxygenase-2 mRNA in the rat spinal cord after peripheral inflammation: an in situ hybridization studyQ73894526
Mechanism of action of nonsteroidal anti-inflammatory drugsQ74509829
N-methyl D-aspartate induced mechanical allodynia is blocked by nitric oxide synthase and cyclooxygenase-2 inhibitorsQ77340853
Role of spinal NO in antiallodynic effect of intrathecal clonidine in neuropathic ratsQ77695455
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)743-748
P577publication date2000-01-01
P1433published inNeuroscienceQ15708571
P1476titleSpinal cyclooxygenase-2 is involved in development of allodynia after nerve injury in rats
P478volume97

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cites work (P2860)
Q46044403COX-1-dependent prostaglandin D2 in microglia contributes to neuropathic pain via DP2 receptor in spinal neurons
Q24649995Capnellene, a natural marine compound derived from soft coral, attenuates chronic constriction injury-induced neuropathic pain in rats
Q36704019Chronic pain after surgery: what can we do to prevent it.
Q35112822Curcumin alleviates neuropathic pain by inhibiting p300/CBP histone acetyltransferase activity-regulated expression of BDNF and cox-2 in a rat model.
Q43157098Leukotriene enhances NMDA-induced inward currents in dorsal horn neurons of the rat spinal cord after peripheral nerve injury
Q28581241Leukotriene synthases and the receptors induced by peripheral nerve injury in the spinal cord contribute to the generation of neuropathic pain
Q34038997Pharmacologic therapies for complex regional pain syndrome
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Q27329693Role of PAF receptor in proinflammatory cytokine expression in the dorsal root ganglion and tactile allodynia in a rodent model of neuropathic pain
Q33942912Role of spinal cyclooxygenase in human postoperative and chronic pain
Q37245429Secondary hyperalgesia in the rat first degree burn model is independent of spinal cyclooxygenase and nitric oxide synthase
Q46897771The effect of cyclooxygenase-2 inhibition on acute and chronic donor-site pain after spinal-fusion surgery
Q36717118Upregulation of nuclear factor of activated T-cells by nerve injury contributes to development of neuropathic pain
Q36571914p300 exerts an epigenetic role in chronic neuropathic pain through its acetyltransferase activity in rats following chronic constriction injury (CCI).

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