IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development.

scientific article published on 8 October 2016

IKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.12527
P932PMC publication ID5363549
P698PubMed publication ID27732959

P50authorAngustias PageQ42353148
Jesus M. ParamioQ43100805
Angel RamirezQ43127788
Manuel NavarroQ47159759
Mª Jesús Fernández-AceñerpQ64780252
P2093author name stringAna Bravo
Marcela Del Río
Josefa P Alameda
Cristian Suárez-Cabrera
María del Carmen Fariña
Rodolfo Moreno-Maldonado
María de Los Llanos Casanova
P2860cites workIKK1-deficient mice exhibit abnormal development of skin and skeletonQ24604269
Increased IKKα expression in the basal layer of the epidermis of transgenic mice enhances the malignant potential of skin tumorsQ27332624
Barrier function of the skin: "la raison d'être" of the epidermisQ28189520
Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeletonQ28235021
Nuclear cytokine-activated IKKalpha controls prostate cancer metastasis by repressing MaspinQ28294196
Deciphering the role of nuclear and cytoplasmic IKKα in skin cancerQ28828173
Signaling to NF-kappaBQ29547844
Missing pieces in the NF-kappaB puzzleQ29547864
IKKalpha regulates mitogenic signaling through transcriptional induction of cyclin D1 via Tcf.Q34177562
ToppGene Suite for gene list enrichment analysis and candidate gene prioritizationQ34982758
Enrichr: a comprehensive gene set enrichment analysis web server 2016 updateQ36007700
Matrix metalloproteinases and tumor metastasisQ36471104
I kappa B kinase alpha (IKKα) activity is required for functional maturation of dendritic cells and acquired immunity to infectionQ36706104
Aberrant IKKα and IKKβ cooperatively activate NF-κB and induce EGFR/AP1 signaling to promote survival and migration of head and neck cancerQ37589257
CYLD regulates keratinocyte differentiation and skin cancer progression in humans.Q38626355
S100A7: A rAMPing up AMP molecule in psoriasis.Q38731589
Molecular mechanisms of constitutive and inducible NF-kappaB activation in oesophageal adenocarcinomaQ38919007
IKK(α) controls canonical TGF(ß)-SMAD signaling to regulate genes expressing SNAIL and SLUG during EMT in panc1 cellsQ39631094
IKKalpha enhances human keratinocyte differentiation and determines the histological variant of epidermal squamous cell carcinomasQ39964601
Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factorQ40389246
A cutaneous gene therapy approach to treat infection through keratinocyte-targeted overexpression of antimicrobial peptidesQ40509451
Ectopic expression of PA2.26 antigen in epidermal keratinocytes leads to destabilization of adherens junctions and malignant progression.Q40840443
Abnormal morphogenesis but intact IKK activation in mice lacking the IKKalpha subunit of IkappaB kinaseQ41644582
Interleukin-17 and Interleukin-22 Induced Proinflammatory Cytokine Production in Keratinocytes via Inhibitor of Nuclear Factor κB Kinase-α ExpressionQ42088686
Limb and skin abnormalities in mice lacking IKKalphaQ42470314
IKKalpha controls formation of the epidermis independently of NF-kappaB.Q42502421
A preclinical model for the analysis of genetically modified human skin in vivoQ43579755
Production of matrix metalloproteinase-9 by activated human monocytes involves a phosphatidylinositol-3 kinase/Akt/IKKalpha/NF-kappaB pathwayQ46412497
Reduction in IkappaB kinase alpha expression promotes the development of skin papillomas and carcinomasQ46972187
IKKalpha is required to maintain skin homeostasis and prevent skin cancer.Q53530644
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammationQ59054264
Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablationQ59403442
Electrophoretic analysis of plasminogen activators in polyacrylamide gels containing sodium dodecyl sulfate and copolymerized substratesQ70645807
P4510describes a project that useslimmaQ112236343
P433issue47
P407language of work or nameEnglishQ1860
P921main subjectskin cancerQ192102
P304page(s)76779-76792
P577publication date2016-11-01
P1433published inOncotargetQ1573155
P1476titleIKKα regulates the stratification and differentiation of the epidermis: implications for skin cancer development
P478volume7

Reverse relations

cites work (P2860)
Q64234089IKKα Promotes the Progression and Metastasis of Non-Small Cell Lung Cancer Independently of its Subcellular Localization
Q48265359LINC00473 antagonizes the tumour suppressor miR-195 to mediate the pathogenesis of Wilms tumour via IKKα.
Q64273058Podoplanin in Inflammation and Cancer
Q96438252lncRNA- RP11-156p1.3, novel diagnostic and therapeutic targeting via CRISPR/Cas9 editing in hepatocellular carcinoma

Search more.