Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region

scientific article published on 24 March 2010

Gene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/NAR/GKQ170
P932PMC publication ID2910050
P698PubMed publication ID20338881
P5875ResearchGate publication ID42589005

P2093author name stringSimon Anderhub
Bernd Epe
Andriy Khobta
Nataliya Kitsera
P2860cites workDestabilized green fluorescent protein detects rapid removal of transcription blocks after genotoxic exposure.Q50666464
8-oxo-guanine bypass by human DNA polymerases in the presence of auxiliary proteinsQ59075328
New Histone Incorporation Marks Sites of UV Repair in Human CellsQ63383593
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG islandQ21092482
Translating the Histone CodeQ22065840
Histone H3.1 and H3.3 complexes mediate nucleosome assembly pathways dependent or independent of DNA synthesisQ24304348
Cloning and characterization of hOGG1, a human homolog of the OGG1 gene of Saccharomyces cerevisiaeQ24317398
HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanismQ24321756
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damageQ24651327
The role of chromatin during transcriptionQ27860995
Chromatin modifications and their functionQ27861067
Transcription factor-specific requirements for coactivators and their acetyltransferase functionsQ28260156
Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylaseQ28507243
RNA polymerase is poised for activation across the genomeQ29615047
Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodGQ29616532
The histone variant H3.3 marks active chromatin by replication-independent nucleosome assemblyQ29618256
Two-polymerase mechanisms dictate error-free and error-prone translesion DNA synthesis in mammalsQ33400985
Silencing of transgene transcription precedes methylation of promoter DNA and histone H3 lysine 9.Q34107315
Opposite base-dependent reactions of a human base excision repair enzyme on DNA containing 7,8-dihydro-8-oxoguanine and abasic sitesQ34250273
Single-stranded breaks in DNA but not oxidative DNA base damages block transcriptional elongation by RNA polymerase II in HeLa cell nuclear extracts.Q34300281
Effect of oxidative DNA damage in promoter elements on transcription factor bindingQ34706510
RNA polymerase II bypass of oxidative DNA damage is regulated by transcription elongation factorsQ35191105
Methylene blue plus light mediates 8-hydroxy 2'-deoxyguanosine formation in DNA preferentially over strand breakageQ35907978
Altered histone H1 stoichiometry and an absence of nucleosome positioning on transfected DNA.Q35920560
Measurement of DNA mismatch repair activity in live cellsQ36828042
Genome maintenance mechanisms are critical for preventing cancer as well as other aging-associated diseasesQ36858337
Nucleocytoplasmic transport of DNA: enhancing non-viral gene transfer.Q36903016
8-Oxoguanine-mediated transcriptional mutagenesis causes Ras activation in mammalian cellsQ36999922
Role of the cytomegalovirus major immediate early enhancer in acute infection and reactivation from latencyQ37039648
Cytotoxicity and mutagenicity of endogenous DNA base lesions as potential cause of human agingQ37114989
Heterochromatin protein 1 is recruited to various types of DNA damage.Q37263966
8-Oxoguanine DNA glycosylase (Ogg1) causes a transcriptional inactivation of damaged DNA in the absence of functional Cockayne syndrome B (Csb) protein.Q39907989
Transcription through 8-oxoguanine in DNA repair-proficient and Csb(-)/Ogg1(-) DNA repair-deficient mouse embryonic fibroblasts is dependent upon promoter strength and sequence contextQ40107274
Histone H3 lysine 9 methylation and HP1gamma are associated with transcription elongation through mammalian chromatinQ40390690
Analysis of DNA repair using transfection-based host cell reactivation.Q41176275
Effect of 8-oxoguanine on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II.Q43874835
Gene silencing in cancer by histone H3 lysine 27 trimethylation independent of promoter DNA methylationQ44364520
Oxidized guanine lesions as modulators of gene transcription. Altered p50 binding affinity and repair shielding by 7,8-dihydro-8-oxo-2'-deoxyguanosine lesions in the NF-kappaB promoter element.Q44544874
Transcription activities at 8-oxoG lesions in DNA.Q45067806
Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transferQ45862079
HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response.Q46625510
Host cell reactivation of plasmids containing oxidative DNA lesions is defective in Cockayne syndrome but normal in UV-sensitive syndrome fibroblastsQ46675864
Early effects of topoisomerase I inhibition on RNA polymerase II along transcribed genes in human cellsQ46904319
Specific histone patterns and acetylase/deacetylase activity at the breakpoint-cluster region of the human MLL geneQ47755580
DNA damage induced by photosensitizers in cellular and cell-free systemsQ50164001
P275copyright licenseCreative Commons Attribution-NonCommercial 2.5 GenericQ19113746
P6216copyright statuscopyrightedQ50423863
P433issue13
P921main subjectgene silencingQ1431332
P304page(s)4285-4295
P577publication date2010-03-24
P1433published inNucleic Acids ResearchQ135122
P1476titleGene silencing induced by oxidative DNA base damage: association with local decrease of histone H4 acetylation in the promoter region
P478volume38

Reverse relations

cites work (P2860)
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