The emerging role of complex modifications of tRNA(Lys)UUU in signaling pathways

scientific article published on January 2015

The emerging role of complex modifications of tRNA(Lys)UUU in signaling pathways is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.15698/MIC2015.01.185
P932PMC publication ID4374736
P698PubMed publication ID25821779
P5875ResearchGate publication ID274262541

P50authorValérie de Crécy-LagardQ84288090
P2093author name stringPatrick C Thiaville
P2860cites workPosttranscriptional RNA Modifications: playing metabolic games in a cell's chemical LegolandQ26849515
Elevated levels of two tRNA species bypass the requirement for elongator complex in transcription and exocytosis.Q27934002
Gcn4 misregulation reveals a direct role for the evolutionary conserved EKC/KEOPS in the t6A modification of tRNAsQ27934109
Distinct subsets of Sit4 holophosphatases are required for inhibition of Saccharomyces cerevisiae growth by rapamycin and zymocinQ27935021
Sua5p a single-stranded telomeric DNA-binding protein facilitates telomere replicationQ27936111
The yeast elongator histone acetylase requires Sit4-dependent dephosphorylation for toxin-target capacity.Q27937480
The T box mechanism: tRNA as a regulatory moleculeQ28265478
Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in miceQ28508971
Loss of a conserved tRNA anticodon modification perturbs cellular signalingQ28535022
Transcriptional profiling shows that Gcn4p is a master regulator of gene expression during amino acid starvation in yeastQ29614487
Translational regulation of GCN4 and the general amino acid control of yeastQ29615275
The TOR signaling cascade regulates gene expression in response to nutrientsQ29620801
The Drosophila EKC/KEOPS complex: roles in protein synthesis homeostasis and animal growthQ33728139
Elongator complex influences telomeric gene silencing and DNA damage response by its role in wobble uridine tRNA modificationQ34017522
In vitro biosynthesis of a universal t6A tRNA modification in Archaea and EukaryaQ34034860
Modification of tRNA(Lys) UUU by elongator is essential for efficient translation of stress mRNAs.Q34846015
tRNA thiolation links translation to stress responses in Saccharomyces cerevisiaeQ34960691
Translational control of cell division by ElongatorQ36073480
tRNA tKUUU, tQUUG, and tEUUC wobble position modifications fine-tune protein translation by promoting ribosome A-site binding.Q37049384
Sulfur amino acids regulate translational capacity and metabolic homeostasis through modulation of tRNA thiolationQ37133127
Loss of wobble uridine modification in tRNA anticodons interferes with TOR pathway signalingQ37698279
ppGpp: magic beyond RNA polymeraseQ37984220
Biosynthesis and function of posttranscriptional modifications of transfer RNAsQ38035925
Drosophila p53-related protein kinase is required for PI3K/TOR pathway-dependent growth.Q42434866
Familial dysautonomia (FD) patients have reduced levels of the modified wobble nucleoside mcm(5)s(2)U in tRNA.Q48434672
P433issue1
P304page(s)1-4
P577publication date2015-01-01
P1433published inMicrobial cell (Graz, Austria)Q56298176
P1476titleThe emerging role of complex modifications of tRNA(Lys)UUU in signaling pathways
P478volume2

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cites work (P2860)
Q45329525A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents
Q28553122Anticodon Modifications in the tRNA Set of LUCA and the Fundamental Regularity in the Standard Genetic Code
Q90240721Can Protein Expression Be Regulated by Modulation of tRNA Modification Profiles?
Q41244150Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNALysUUU modifications
Q41833611Global translational impacts of the loss of the tRNA modification t6A in yeast.
Q92650205KAE1 Allelic Variants Affect TORC1 Activation and Fermentation Kinetics in Saccharomyces cerevisiae
Q89834374Loss of Elongator- and KEOPS-Dependent tRNA Modifications Leads to Severe Growth Phenotypes and Protein Aggregation in Yeast
Q36529455Novel base-pairing interactions at the tRNA wobble position crucial for accurate reading of the genetic code
Q26752314Nucleoside modifications in the regulation of gene expression: focus on tRNA

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