Excessive activation of the TLR9/TGF-β1/PDGF-B pathway in the peripheral blood of patients with systemic lupus erythematosus

scientific article published on 29 March 2017

Excessive activation of the TLR9/TGF-β1/PDGF-B pathway in the peripheral blood of patients with systemic lupus erythematosus is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1084252259
P356DOI10.1186/S13075-017-1238-8
P932PMC publication ID5372299
P698PubMed publication ID28356164

P2093author name stringXiaosong Wang
Jing Sun
Yi Yuan
Genhong Cheng
Lili Song
Mingyue Yang
Zhenyu Jiang
Xue Diao
Kuo Wang
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Toll-like receptor 9 enhances nephritogenic immunity and glomerular leukocyte recruitment, exacerbating experimental crescentic glomerulonephritis.Q34254371
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Platelet-derived growth factor-BB induces renal tubulointerstitial myofibroblast formation and tubulointerstitial fibrosis.Q35773580
TNF-α and TGF-β counter-regulate PD-L1 expression on monocytes in systemic lupus erythematosusQ35795451
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Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotidesQ38289912
Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) miceQ38345765
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Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigensQ42261747
Activation profile of Toll-like receptors of peripheral blood lymphocytes in patients with systemic lupus erythematosus.Q43258243
Synthetic CpG oligodeoxynucleotides accelerate the development of lupus nephritis during preactive phase in NZB x NZWF1 miceQ44687455
Treatment with anti-TGF-beta antibody ameliorates chronic progressive nephritis by inhibiting Smad/TGF-beta signalingQ44692945
Urinary transforming growth factor-beta 1 in various types of nephropathyQ44730407
Amelioration of autoimmune nephritis by imatinib in MRL/lpr miceQ46829591
Toll-like receptor 9 signaling protects against murine lupusQ46872996
Levels of transforming growth factor-beta are low in systemic lupus erythematosus patients with active disease.Q53170451
Systemic lupus erythematosusQ55933861
Imatinib ameliorates renal disease and survival in murine lupus autoimmune diseaseQ57702684
Recombinant human anti–transforming growth factor β1 antibody therapy in systemic sclerosis: A multicenter, randomized, placebo-controlled phase I/II trial of CAT-192Q61646585
PDGF and TGF-beta contribute to the natural course of human IgA glomerulonephritisQ70847479
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Gene expression of PDGF and PDGF receptor in various forms of glomerulonephritisQ73126828
Specialization and complementarity in microbial molecule recognition by human myeloid and plasmacytoid dendritic cellsQ77357447
Expansion of toll-like receptor 9-expressing B cells in active systemic lupus erythematosus: implications for the induction and maintenance of the autoimmune processQ79318117
Measurement of cytokine production using whole bloodQ81142261
Expression of Toll-like receptor 9 in renal podocytes in childhood-onset active and inactive lupus nephritisQ83022836
Role of Treg cells and TGF-β1 in patients with systemic lupus erythematosus: a possible relation with lupus nephritisQ84080695
Distinct autoantibody profiles in systemic lupus erythematosus patients are selectively associated with TLR7 and TLR9 upregulationQ86553655
Effect of renal disease on the standardized mortality ratio and life expectancy of patients with systemic lupus erythematosusQ86932194
P433issue1
P921main subjectsystemic lupus erythematosusQ1485
toll-like receptorQ408004
P304page(s)70
P577publication date2017-03-29
P1433published inArthritis Research and TherapyQ15757229
P1476titleExcessive activation of the TLR9/TGF-β1/PDGF-B pathway in the peripheral blood of patients with systemic lupus erythematosus
P478volume19

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cites work (P2860)
Q55163735Aberrant T Cell Signaling and Subsets in Systemic Lupus Erythematosus.
Q91526078Cytokine signatures associate with disease severity in children with Mycoplasma pneumoniae pneumonia
Q42374957Interleukin 17A as a good predictor of the severity of Mycoplasma pneumoniae pneumonia in children
Q52726017Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis.
Q52725381The non-haemostatic role of platelets in systemic lupus erythematosus.
Q55410580Transcriptome Analysis of Bronchoalveolar Lavage Fluid From Children With Mycoplasma pneumoniae Pneumonia Reveals Natural Killer and T Cell-Proliferation Responses.

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