Synthetic CpG oligodeoxynucleotides accelerate the development of lupus nephritis during preactive phase in NZB x NZWF1 mice

scientific article

Synthetic CpG oligodeoxynucleotides accelerate the development of lupus nephritis during preactive phase in NZB x NZWF1 mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1191/0961203303LU483OA
P698PubMed publication ID14667100

P2093author name stringT Hayashi
K Hasegawa
P2860cites workIncreased spontaneous secretion of IL-6 from B cells of patients with B chronic lymphatic leukaemia (B-CLL) and autoimmunityQ41671494
CpG-DNA derived from sera in systemic lupus erythematosus enhances ICAM-1 expression on endothelial cellsQ42100130
Promotion of lupus in NZB x NZWF1 mice by plasmids encoding interferon (IFN)-gamma but not by those encoding interleukin (IL)-4.Q44158780
CpG oligodeoxynucleotides accelerate reovirus type 2-triggered insulitis in DBA/1 suckling miceQ44365151
IL-6 receptor blockage inhibits the onset of autoimmune kidney disease in NZB/W F1 miceQ47901598
Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cellsQ47915755
Response of peripheral blood mononuclear cells from lupus patients to stimulation by CpG oligodeoxynucleotidesQ56897931
A Toll-like receptor recognizes bacterial DNAQ24290668
CpG motifs present in bacteria DNA rapidly induce lymphocytes to secrete interleukin 6, interleukin 12, and interferon gammaQ24568172
Anti-dsDNA antibody up-regulates interleukin 6, but not cyclo-oxygenase, gene expression in glomerular mesangial cells: a marker of immune-mediated renal damage?Q32108129
The antigenic properties of bacterial DNA in normal and aberrant immunityQ34005461
Interleukin 6 promotes murine lupus in NZB/NZW F1 miceQ34228814
Treatment of murine lupus with cDNA encoding IFN-gammaR/FcQ35126621
Pathogenesis of the glomerulonephritis of NZB/W miceQ36269048
Immunostimulatory oligodeoxynucleotides promote protective immunity and provide systemic therapy for leishmaniasis via IL-12- and IFN-gamma-dependent mechanismsQ36386875
CpG DNA: a pathogenic factor in systemic lupus erythematosus?Q40954780
Immune activation by bacterial DNA: a new genetic codeQ41182494
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectlupus nephritisQ1621830
P304page(s)838-845
P577publication date2003-01-01
P1433published inLupusQ6704846
P1476titleSynthetic CpG oligodeoxynucleotides accelerate the development of lupus nephritis during preactive phase in NZB x NZWF1 mice
P478volume12

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cites work (P2860)
Q44349028A safety study of a B-class CpG ODN in Sprague-Dawley rats
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Q36868322Antiinfective applications of toll-like receptor 9 agonists
Q83116640Autoantibodies in systemic lupus erythematosus
Q37944412Cellular and molecular pathogenesis of systemic lupus erythematosus: lessons from animal models
Q33941433Dendritic cells in systemic lupus erythematosus
Q35031736Dysfunction of lacrimal and salivary glands in Sjögren's syndrome: nonimmunologic injury in preinflammatory phase and mouse model
Q34619324Early development of the Toll-like receptor 9 agonist, PF-3512676, for the treatment of patients with advanced cancers
Q81277364Elimination of CD4(+)CD25(+) T cell accelerates the development of glomerulonephritis during the preactive phase in autoimmune-prone female NZB x NZW F mice
Q42135044Excessive activation of the TLR9/TGF-β1/PDGF-B pathway in the peripheral blood of patients with systemic lupus erythematosus
Q41670053HM71224, a selective Bruton's tyrosine kinase inhibitor, attenuates the development of murine lupus
Q36793158Identification of type I interferon-associated inflammation in the pathogenesis of cutaneous lupus erythematosus opens up options for novel therapeutic approaches.
Q36526351Immune mechanisms and therapeutic potential of CpG oligodeoxynucleotides
Q36150438Immunostimulatory oligonucleotides in therapy of allergic diseases
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Q36068780Inhibitory oligodeoxynucleotides - therapeutic promise for systemic autoimmune diseases?
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Q50571950Polarization toward Th1-type response in active, but not in inactive, lupus inhibits late allergic rhinitis in lupus-prone female NZB×NZWF(1) mice.
Q37801738Role for toll-like receptors in autoimmune disease: The example of systemic lupus erythematosus
Q36961012Structural requirements and applications of inhibitory oligodeoxyribonucleotides
Q56897860Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB × NZW mice
Q38072067Synthetic adjuvants for vaccine formulations: phytol derivatives
Q64972967Systemic administration of olygodeoxynucleotides with CpG motifs at priming phase reduces local Th2 response and late allergic rhinitis in BALB/c mice.
Q36673286Systemic lupus erythematosus: multiple immunological phenotypes in a complex genetic disease.
Q38329839TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production.
Q34106220Therapeutic Strategies for SLE Involving Cytokines: Mechanism-Oriented Therapies Especially IFN- Targeting Gene Therapy
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Q35790879Use of CpG oligodeoxynucleotides as immunoprotective agents

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