EGFR signaling promotes inflammation and cancer stem-like activity in inflammatory breast cancer

scientific article published on 4 July 2017

EGFR signaling promotes inflammation and cancer stem-like activity in inflammatory breast cancer is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.18632/ONCOTARGET.18958
P932PMC publication ID5620223
P698PubMed publication ID28978083

P50authorGabriel N HortobagyiQ88225186
P2093author name stringXiaoping Wang
Dongwei Zhang
Debu Tripathy
Peiying Yang
Chandra Bartholomeusz
Naoto T Ueno
Wendy A Woodward
James M Reuben
Yun Gong
Hiroko Masuda
Takahiro Kogawa
Bedrich L Eckhardt
Yohei Funakoshi
David A Pirman
Monica E Reyes
Adriana P Trape
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Mesenchymal stem cells promote mammosphere formation and decrease E-cadherin in normal and malignant breast cellsQ33680909
Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancerQ33870504
Prognostic influence of cyclooxygenase-2 protein and mRNA expression in node-negative breast cancer patientsQ34996098
Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancerQ35007782
International expert panel on inflammatory breast cancer: consensus statement for standardized diagnosis and treatmentQ35017523
Update on the management of inflammatory breast cancerQ35108008
The role of COX-2 in intestinal inflammation and colorectal cancerQ35234704
Mesenchymal stem cells mediate the clinical phenotype of inflammatory breast cancer in a preclinical modelQ35313206
Relationship of sialyl-Lewis(x/a) underexpression and E-cadherin overexpression in the lymphovascular embolus of inflammatory breast carcinomaQ35747568
Inflammatory breast cancer: a reviewQ36121844
Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity.Q36134167
Isolation and characterization of a new human breast cancer cell line, KPL-4, expressing the Erb B family receptors and interleukin-6.Q36618907
COX-2 modulates mammary tumor progression in response to collagen density.Q36715145
Nodal expression in triple-negative breast cancer: Cellular effects of its inhibition following doxorubicin treatmentQ36956874
Defining the molecular biology of inflammatory breast cancerQ37097306
Nodal promotes invasive phenotypes via a mitogen-activated protein kinase-dependent pathwayQ37259888
Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lungQ37429876
Nodal promotes the self-renewal of human colon cancer stem cells via an autocrine manner through Smad2/3 signaling pathwayQ37627063
Mesenchymal stem cells and macrophages interact through IL-6 to promote inflammatory breast cancer in pre-clinical modelsQ37696160
Nodal signaling activates the Smad2/3 pathway to regulate stem cell-like properties in breast cancer cellsQ37743505
Multiple drug resistance mechanisms in cancerQ37780709
A novel putative low-affinity insulin-like growth factor-binding protein, LIBC (lost in inflammatory breast cancer), and RhoC GTPase correlate with the inflammatory breast cancer phenotype.Q38467243
COX2 overexpression is a prognostic marker for Stage III breast cancerQ38474547
New Insights on COX-2 in Chronic Inflammation Driving Breast Cancer Growth and Metastasis.Q38550876
Plasticity underlies tumor progression: role of Nodal signalingQ38764247
Early clinical development of epidermal growth factor receptor targeted therapy in breast cancerQ39167876
Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness.Q39379114
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Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancerQ39893964
Prostaglandin E2 transactivates EGF receptor: a novel mechanism for promoting colon cancer growth and gastrointestinal hypertrophyQ40747279
Quantitative high-performance liquid chromatography/electrospray ionization tandem mass spectrometric analysis of 2- and 3-series prostaglandins in cultured tumor cellsQ44137975
Prostaglandin E2 regulates cell migration via the intracellular activation of the epidermal growth factor receptorQ44375278
Prostaglandin E2 stimulates the growth of colon cancer cells via induction of amphiregulinQ44590607
TIG1 promotes the development and progression of inflammatory breast cancer through activation of Axl kinase.Q53090999
Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.Q53279352
Increased angiogenesis and lymphangiogenesis in inflammatory versus noninflammatory breast cancer by real-time reverse transcriptase-PCR gene expression quantification.Q54690251
An inflammatory linkQ59081065
Inflammatory breast cancer: the experience of the surveillance, epidemiology, and end results (SEER) programQ69833744
Expression of growth factor and chemokine receptors: new insights in the biology of inflammatory breast cancerQ79918235
P433issue40
P407language of work or nameEnglishQ1860
P304page(s)67904-67917
P577publication date2017-07-04
P1433published inOncotargetQ1573155
P1476titleEGFR signaling promotes inflammation and cancer stem-like activity in inflammatory breast cancer
P478volume8

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cites work (P2860)
Q90161213Comparison of molecular profile in triple-negative inflammatory and non-inflammatory breast cancer not of mesenchymal stem-like subtype
Q93251378Eicosapentaenoic acid in combination with EPHA2 inhibition shows efficacy in preclinical models of triple-negative breast cancer by disrupting cellular cholesterol efflux
Q99630247Identification of key pathways and genes shared between Crohn's disease and breast cancer using bioinformatics analysis
Q63366138Inflammatory breast cancer biology: the tumour microenvironment is key
Q91783003Perspectives on Inflammatory Breast Cancer (IBC) Research, Clinical Management and Community Engagement from the Duke IBC Consortium
Q49887925Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges
Q63366144Safety and Efficacy of Panitumumab Plus Neoadjuvant Chemotherapy in Patients With Primary HER2-Negative Inflammatory Breast Cancer
Q64890079Stapled EGFR peptide reduces inflammatory breast cancer and inhibits additional HER-driven models of cancer.
Q90478729Targeted Delivery of 111In Into the Nuclei of EGFR Overexpressing Cells via Modular Nanotransporters With Anti-EGFR Affibody

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