| scholarly article | Q13442814 |
| P50 | author | Thomas A Einhorn | Q37368119 |
| Rayyan A Kayal | Q42274326 | ||
| Louis Charles Gerstenfeld | Q67658704 | ||
| P2093 | author name string | Dana T Graves | |
| Dan Faibish | |||
| Jazia Alblowi | |||
| Jody McLean | |||
| Michelle Siqueira | |||
| Nanarao Krothapalli | |||
| P2860 | cites work | Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor | Q22009126 |
| Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles | Q24536351 | ||
| Enhanced bone regeneration associated with decreased apoptosis in mice with partial HIF-1alpha deficiency | Q28509277 | ||
| Tumor necrosis factor alpha (TNF-alpha) coordinately regulates the expression of specific matrix metalloproteinases (MMPS) and angiogenic factors during fracture healing. | Q33213072 | ||
| Anti-TNF therapy for rheumatoid arthritis and other inflammatory diseases | Q34450313 | ||
| Type 2 diabetic mice demonstrate slender long bones with increased fragility secondary to increased osteoclastogenesis | Q34923714 | ||
| Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity | Q35029163 | ||
| Tumor necrosis factor alpha activation of the apoptotic cascade in murine articular chondrocytes is associated with the induction of metalloproteinases and specific pro-resorptive factors | Q79163029 | ||
| Gene expression changes with time in skeletal muscle of severely burned children | Q81591545 | ||
| Diabetes enhances mRNA levels of proapoptotic genes and caspase activity, which contribute to impaired healing | Q82410970 | ||
| Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression | Q83056072 | ||
| Tumor necrosis factor-alpha mediates diabetes-enhanced apoptosis of matrix-producing cells and impairs diabetic healing | Q35088004 | ||
| A new view of diabetic retinopathy: a neurodegenerative disease of the eye. | Q35092253 | ||
| Decisions on life and death: FOXO Forkhead transcription factors are in command when PKB/Akt is off duty | Q35139549 | ||
| FOXO transcription factors in cell-cycle regulation and the response to oxidative stress | Q36125022 | ||
| Application of histomorphometric methods to the study of bone repair | Q36256721 | ||
| Dynamic FoxO transcription factors | Q36889897 | ||
| Activation of the acquired immune response reduces coupled bone formation in response to a periodontal pathogen | Q37089072 | ||
| Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment. | Q37238865 | ||
| High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing | Q37362094 | ||
| The influence of diabetes mellitus on the healing of closed fractures. | Q39647861 | ||
| Oxygen tension regulates chondrocyte differentiation and function during endochondral ossification. | Q40244153 | ||
| The bone morphogenetic protein 2 signaling mediator Smad1 participates predominantly in osteogenic and not in chondrogenic differentiation in mesenchymal progenitors C3H10T1/2. | Q40849678 | ||
| Role of morphogenetic proteins in skeletal tissue engineering and regeneration | Q40864602 | ||
| Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5. | Q41032570 | ||
| Bone mineral density and bone metabolism in diabetes mellitus | Q41710701 | ||
| A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells | Q41735342 | ||
| Chondrocyte apoptosis after simulated intraarticular fracture: a comparison of histologic detection methods | Q42131847 | ||
| Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes | Q42522948 | ||
| FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons | Q42918105 | ||
| Expression of caspase-3 and -9 relevant to cartilage destruction and chondrocyte apoptosis in human osteoarthritic cartilage | Q43846414 | ||
| Caspase activation in retinas of diabetic and galactosemic mice and diabetic patients | Q43935487 | ||
| Does diabetes delay fracture healing? | Q44007208 | ||
| The effects of blood glucose control upon fracture healing in the BB Wistar rat with diabetes mellitus | Q44242468 | ||
| Molecular basis for affected cartilage formation and bone union in fracture healing of the streptozotocin-induced diabetic rat. | Q46412507 | ||
| Serum levels of insulin-like growth factor system components and relationship to bone metabolism in Type 1 and Type 2 diabetes mellitus patients | Q46413037 | ||
| The Ins2Akita mouse as a model of early retinal complications in diabetes | Q46508398 | ||
| Increased cathepsin K and tartrate-resistant acid phosphatase expression in bone of streptozotocin-induced diabetic rats | Q46966368 | ||
| Active role of chondrocyte apoptosis in endochondral ossification. | Q51093499 | ||
| Three-dimensional reconstruction of fracture callus morphogenesis. | Q52011688 | ||
| Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption. | Q52100443 | ||
| Bone formation is impaired in a model of type 1 diabetes. | Q53568790 | ||
| Histomorphometric analysis of diabetic osteopenia in streptozotocin-induced diabetic mice: a possible role of oxidative stress. | Q53575266 | ||
| FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis. | Q54686792 | ||
| Advanced glycation end products induce apoptosis in fibroblasts through activation of ROS, MAP kinases, and the FOXO1 transcription factor | Q58029351 | ||
| TNF-α antibodies and osteoprotegerin decrease systemic bone loss associated with inflammation through distinct mechanisms in collagen-induced arthritis | Q61833005 | ||
| Retardation of bone fracture healing in experimental diabetes | Q69218424 | ||
| Chondrocyte apoptosis in endochondral ossification of chick sterna | Q71578420 | ||
| Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology | Q73958624 | ||
| Programmed removal of chondrocytes during endochondral fracture healing | Q74493974 | ||
| Induction of apoptosis in chondrocytes by tumor necrosis factor-alpha | Q74525810 | ||
| Bone mineral density in patients with type 1 and type 2 diabetes | Q77945576 | ||
| P433 | issue | 7 | |
| P921 | main subject | apoptotic process | Q14599311 |
| bone fracture | Q68833 | ||
| P304 | page(s) | 1604-1615 | |
| P577 | publication date | 2010-07-01 | |
| P1433 | published in | Journal of Bone and Mineral Research | Q15750941 |
| P1476 | title | TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1 | |
| P478 | volume | 25 |
| Q91982037 | AdipoRon promotes diabetic fracture repair through endochondral ossification-based bone repair by enhancing survival and differentiation of chondrocytes |
| Q46716762 | Alcohol-related deficient fracture healing is associated with activation of FoxO transcription factors in mice |
| Q46427364 | Apoptosis of periodontium cells in streptozototocin- and ligature-induced experimental diabetic periodontitis in rats |
| Q36315765 | Augmented LPS responsiveness in type 1 diabetes-derived osteoclasts |
| Q47111511 | Bacterial infection increases periodontal bone loss in diabetic rats through enhanced apoptosis |
| Q58609660 | Bidirectional regulation of osteogenic differentiation by the FOXO subfamily of Forkhead transcription factors in mammalian MSCs |
| Q36493877 | Bisphosphonate treatment of type I diabetic mice prevents early bone loss but accentuates suppression of bone formation |
| Q41782043 | Chemokine expression is upregulated in chondrocytes in diabetic fracture healing |
| Q57803472 | Chondrocytes promote vascularization in fracture healing through a FOXO1 dependent mechanism |
| Q46292840 | Delayed bone regeneration and low bone mass in a rat model of insulin-resistant type 2 diabetes mellitus is due to impaired osteoblast function |
| Q36407732 | Diabetes and Its Effect on Bone and Fracture Healing. |
| Q38776127 | Diabetes and disordered bone metabolism (diabetic osteodystrophy): time for recognition |
| Q37965266 | Diabetes and fracture healing: the skeletal effects of diabetic drugs |
| Q26852990 | Diabetes mellitus related bone metabolism and periodontal disease |
| Q35137241 | Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism |
| Q40096097 | Diabetes-induced fibrotic matrix inhibits intramembranous bone healing |
| Q38972516 | Effects of Type 1 Diabetes on Osteoblasts, Osteocytes, and Osteoclasts. |
| Q55261710 | Effects of obesity on the healing of bone fracture in mice. |
| Q33594004 | FOXO transcription factors: their clinical significance and regulation. |
| Q57045573 | FOXO1 Deletion Reverses the Effect of Diabetic-Induced Impaired Fracture Healing |
| Q41621420 | FOXO1 deletion in keratinocytes improves diabetic wound healing through MMP9 regulation |
| Q35543164 | FOXO1 differentially regulates both normal and diabetic wound healing |
| Q34359097 | FOXO1, TGF-β regulation and wound healing |
| Q34626746 | FoxO transcription factors support oxidative stress resistance in human chondrocytes |
| Q38069459 | FoxO1 is crucial for sustaining cardiomyocyte metabolism and cell survival |
| Q37980336 | Fracture healing under healthy and inflammatory conditions |
| Q26851958 | Fracture healing: mechanisms and interventions |
| Q41159150 | Gene expression dynamics during diabetic periodontitis |
| Q90419968 | Impact of Diabetes Mellitus on Bone Health |
| Q35648310 | Impaired Fracture Healing Caused by Deficiency of the Immunoreceptor Adaptor Protein DAP12. |
| Q37694066 | Impaired osteogenesis of T1DM bone marrow-derived stromal cells and periosteum-derived cells and their differential in-vitro responses to growth factor rescue. |
| Q37789186 | Inflammation as death or life signal in diabetic fracture healing. |
| Q60628154 | Influence of Menopause on Inflammatory Cytokines during Murine and Human Bone Fracture Healing |
| Q58419491 | Interactions Between Multipotential Stromal Cells (MSCs) and Immune Cells During Bone Healing |
| Q92738054 | Lentiviral‑mediated Shh reverses the adverse effects of high glucose on osteoblast function and promotes bone formation via Sonic hedgehog signaling |
| Q35970838 | Loss of Bone and Wnt10b Expression in Male Type 1 Diabetic Mice Is Blocked by the Probiotic Lactobacillus reuteri. |
| Q37005199 | Low dose aspirin therapy decreases blood glucose levels but does not prevent type i diabetes-induced bone loss |
| Q47119870 | MiR-29b-3p promotes chondrocyte apoptosis and facilitates the occurrence and development of osteoarthritis by targeting PGRN. |
| Q37662730 | Modulation of macrophage activity during fracture repair has differential effects in young adult and elderly mice |
| Q90406506 | Molecular pathogenesis of fracture nonunion |
| Q48873501 | Pharmacological rescue of diabetic skeletal stem cell niches. |
| Q35126620 | Plasminogen activator inhibitor-1 is involved in impaired bone repair associated with diabetes in female mice |
| Q91924941 | Ras associated with diabetes may play a role in fracture nonunion development in rats |
| Q37858842 | Review: The diabetic bone: a cellular and molecular perspective |
| Q60932159 | Role of Forkhead Box O Transcription Factors in Oxidative Stress-Induced Chondrocyte Dysfunction: Possible Therapeutic Target for Osteoarthritis? |
| Q35791713 | Role of forkhead transcription factors in diabetes-induced oxidative stress |
| Q28573912 | SIRT1 inhibits TNF-α-induced apoptosis of vascular adventitial fibroblasts partly through the deacetylation of FoxO1 |
| Q50021725 | Skeletal fragility in diabetes |
| Q37722128 | Surgically‑induced mouse models in the study of bone regeneration: Current models and future directions (Review). |
| Q54996755 | TNFα contributes to diabetes impaired angiogenesis in fracture healing. |
| Q58109102 | The Cellular Biology of Fracture Healing |
| Q49294423 | The Impact of Type 2 Diabetes on Bone Fracture Healing |
| Q52366183 | The Role of the Immune Cells in Fracture Healing. |
| Q92881718 | The Roles of FoxO Transcription Factors in Regulation of Bone Cells Function |
| Q35683050 | The convergence of fracture repair and stem cells: interplay of genes, aging, environmental factors and disease |
| Q92971753 | The protective effect of bone marrow-derived mesenchymal stem cells in liver ischemia/reperfusion injury via down-regulation of miR-370 |
| Q47151037 | Tumor necrosis factor-α antagonist diminishes osteocytic RANKL and sclerostin expression in diabetes rats with periodontitis. |
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