| scholarly article | Q13442814 |
| P50 | author | Thomas A Einhorn | Q37368119 |
| Rayyan A Kayal | Q42274326 | ||
| P2093 | author name string | Dana T Graves | |
| Erin McKenzie | |||
| Jazia Alblowi | |||
| Louis Gerstenfeld | |||
| Barbara Nikolajczyk | |||
| Jason Conn | |||
| Jody McLean | |||
| Michelle Siqueira | |||
| Nanarao Krothapalli | |||
| P2860 | cites work | Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles | Q24536351 |
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| Biomechanical evaluation of early fracture healing in normal and diabetic rats | Q30305469 | ||
| Alterations of cartilage and collagen expression during fracture healing in experimental diabetes | Q30306094 | ||
| BMP treatment of C3H10T1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis. | Q31028194 | ||
| Lower bone mineral content in children with type 1 diabetes mellitus is linked to female sex, low insulin-like growth factor type I levels, and high insulin requirement | Q33250630 | ||
| Comparison of effects of the bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing. | Q33385262 | ||
| Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction | Q33886695 | ||
| Resorption of bone by isolated rabbit osteoclasts | Q34268059 | ||
| Diminished bone formation during diabetic fracture healing is related to the premature resorption of cartilage associated with increased osteoclast activity | Q35029163 | ||
| Regulation of cell survival and proliferation by the FOXO (Forkhead box, class O) subfamily of Forkhead transcription factors | Q35053112 | ||
| Fracture healing as a post-natal developmental process: molecular, spatial, and temporal aspects of its regulation. | Q35077692 | ||
| FoxOs at the crossroads of cellular metabolism, differentiation, and transformation | Q35770614 | ||
| Application of histomorphometric methods to the study of bone repair | Q36256721 | ||
| Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment. | Q37238865 | ||
| TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand | Q37413745 | ||
| Tumor necrosis factor alpha regulates expression of the major histocompatibility complex class II-associated invariant chain by binding of an NF-kappa B-like factor to a promoter element | Q38339930 | ||
| Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis | Q38360588 | ||
| The influence of diabetes mellitus on the healing of closed fractures. | Q39647861 | ||
| FOXO transcription factor activation by oxidative stress mediated by the small GTPase Ral and JNK. | Q40493379 | ||
| Wnt signaling during BMP-2 stimulation of mesenchymal chondrogenesis | Q40752065 | ||
| Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells | Q40927574 | ||
| Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5. | Q41032570 | ||
| Blockade of receptor for advanced glycation end-products restores effective wound healing in diabetic mice. | Q41893958 | ||
| Diabetes enhances periodontal bone loss through enhanced resorption and diminished bone formation | Q42072774 | ||
| Expression of osteoprotegerin, receptor activator of NF-kappaB ligand (osteoprotegerin ligand) and related proinflammatory cytokines during fracture healing. | Q42505465 | ||
| FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons | Q42918105 | ||
| Diabetes and risk of fracture: The Blue Mountains Eye Study | Q43651870 | ||
| Calcaneal ultrasonometry in patients with Charcot osteoarthropathy and its relationship with densitometry in the lumbar spine and femoral neck and with markers of bone turnover | Q43687480 | ||
| Retardation of fracture healing in experimental diabetes | Q43757418 | ||
| Does diabetes delay fracture healing? | Q44007208 | ||
| Serum levels of insulin-like growth factor system components and relationship to bone metabolism in Type 1 and Type 2 diabetes mellitus patients | Q46413037 | ||
| Osteoclastic function is accelerated in male patients with type 2 diabetes mellitus: the preventive role of osteoclastogenesis inhibitory factor/osteoprotegerin (OCIF/OPG) on the decrease of bone mineral density | Q46462609 | ||
| Relative fracture risk in patients with diabetes mellitus, and the impact of insulin and oral antidiabetic medication on relative fracture risk | Q46503292 | ||
| Acute Charcot arthropathy successfully treated with pamidronate: long-term follow-up | Q46752274 | ||
| Chondrogenic differentiation of murine C3H10T1/2 multipotential mesenchymal cells: I. Stimulation by bone morphogenetic protein-2 in high-density micromass cultures. | Q50518954 | ||
| Measurement of markers of osteoclast and osteoblast activity in patients with acute and chronic diabetic Charcot neuroarthropathy. | Q50946684 | ||
| Three-dimensional reconstruction of fracture callus morphogenesis. | Q52011688 | ||
| Impaired fracture healing in the absence of TNF-alpha signaling: the role of TNF-alpha in endochondral cartilage resorption. | Q52100443 | ||
| Oxidative stress antagonizes Wnt signaling in osteoblast precursors by diverting beta-catenin from T cell factor- to forkhead box O-mediated transcription. | Q53541681 | ||
| FOXO1 functions as a master switch that regulates gene expression necessary for tumor necrosis factor-induced fibroblast apoptosis. | Q54686792 | ||
| Diabetes mellitus and healing of closed fractures | Q68095573 | ||
| Factors influencing survival following fractures of the upper end of the femur | Q69642199 | ||
| Bone loss and bone turnover in diabetes | Q72332597 | ||
| Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology | Q73958624 | ||
| Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women | Q74086478 | ||
| Bone mineral density in patients with type 1 and type 2 diabetes | Q77945576 | ||
| The urinary excretion of deoxypyridinium cross-links is higher in diabetic than in nondiabetic adolescents | Q78077246 | ||
| Diabetes causes decreased osteoclastogenesis, reduced bone formation, and enhanced apoptosis of osteoblastic cells in bacteria stimulated bone loss | Q79117033 | ||
| Tumor necrosis factor alpha activation of the apoptotic cascade in murine articular chondrocytes is associated with the induction of metalloproteinases and specific pro-resorptive factors | Q79163029 | ||
| Plasma levels of tumour necrosis factor-alpha in patients with chronic periodontitis and type 2 diabetes | Q79371948 | ||
| Analysis of fracture healing by large-scale transcriptional profile identified temporal relationships between metalloproteinase and ADAMTS mRNA expression | Q83056072 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | bone fracture | Q68833 |
| cartilage | Q502730 | ||
| P304 | page(s) | 1574-1585 | |
| P577 | publication date | 2009-09-10 | |
| P1433 | published in | The American Journal of Pathology | Q4744259 |
| P1476 | title | High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing | |
| P478 | volume | 175 |
| Q43240676 | Abnormal cell responses and role of TNF-α in impaired diabetic wound healing |
| Q47566350 | Association of Bone Metabolic Markers With Diabetic Retinopathy and Diabetic Macular Edema in Elderly Chinese Individuals With Type 2 Diabetes Mellitus |
| Q36315765 | Augmented LPS responsiveness in type 1 diabetes-derived osteoclasts |
| Q36493877 | Bisphosphonate treatment of type I diabetic mice prevents early bone loss but accentuates suppression of bone formation |
| Q41782043 | Chemokine expression is upregulated in chondrocytes in diabetic fracture healing |
| Q57803472 | Chondrocytes promote vascularization in fracture healing through a FOXO1 dependent mechanism |
| Q34794967 | Constructing the toolbox: Patient-specific genetic factors of altered fracture healing |
| Q41620772 | Cytocompatible Anti-microbial Dressings of Syzygium cumini Cellulose Nanocrystals Decorated with Silver Nanoparticles Accelerate Acute and Diabetic Wound Healing |
| Q33727997 | Delayed fracture healing and increased callus adiposity in a C57BL/6J murine model of obesity-associated type 2 diabetes mellitus |
| Q36407732 | Diabetes and Its Effect on Bone and Fracture Healing. |
| Q26852990 | Diabetes mellitus related bone metabolism and periodontal disease |
| Q35137241 | Diabetes reduces mesenchymal stem cells in fracture healing through a TNFα-mediated mechanism |
| Q28392350 | Effect of isolated hyperglycemia on native mechanical and biologic shoulder joint properties in a rat model |
| Q53577470 | Effects of local vanadium delivery on diabetic fracture healing. |
| Q92287484 | Experimental arthritis and Porphyromonas gingivalis administration synergistically decrease bone regeneration in femoral cortical defects |
| Q33594004 | FOXO transcription factors: their clinical significance and regulation. |
| Q57045573 | FOXO1 Deletion Reverses the Effect of Diabetic-Induced Impaired Fracture Healing |
| Q35164358 | FOXO1 mediates RANKL-induced osteoclast formation and activity |
| Q37267966 | FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stress |
| Q37980336 | Fracture healing under healthy and inflammatory conditions |
| Q26851958 | Fracture healing: mechanisms and interventions |
| Q33746706 | From isolation to implantation: a concise review of mesenchymal stem cell therapy in bone fracture repair |
| Q41159150 | Gene expression dynamics during diabetic periodontitis |
| Q35570026 | Harnessing and modulating inflammation in strategies for bone regeneration. |
| Q53414641 | Impaired healing of fragility fractures in type 2 diabetes: clinical and radiographic assessments and serum cytokine levels. |
| Q33761069 | Influence of antiTNF-alpha antibody treatment on fracture healing under chronic inflammation |
| Q39226629 | Inhibition of fracture healing in the presence of contamination by Staphylococcus aureus: Effects of growth state and immune response |
| Q58419491 | Interactions Between Multipotential Stromal Cells (MSCs) and Immune Cells During Bone Healing |
| Q35970838 | Loss of Bone and Wnt10b Expression in Male Type 1 Diabetic Mice Is Blocked by the Probiotic Lactobacillus reuteri. |
| Q37005199 | Low dose aspirin therapy decreases blood glucose levels but does not prevent type i diabetes-induced bone loss |
| Q35822559 | Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response. |
| Q42383995 | MMP9 regulates the cellular response to inflammation after skeletal injury |
| Q90406506 | Molecular pathogenesis of fracture nonunion |
| Q58695435 | N-Acetylcysteine (NAC) Ameliorates Lipid-Related Metabolic Dysfunction in Bone Marrow Stromal Cells-Derived Adipocytes |
| Q91912587 | Osteoarthritis and type 2 diabetes: From pathogenetic factors to therapeutic intervention |
| Q37096266 | Palmitic acid and DGAT1 deficiency enhance osteoclastogenesis, while oleic acid-induced triglyceride formation prevents it |
| Q48873501 | Pharmacological rescue of diabetic skeletal stem cell niches. |
| Q92647341 | Postoperative Serum Levels of Interleukin-1β (IL-1β), Interleukin-17 (IL-17), and Tumor Necrosis Factor-α (TNF-α) in Patients Following Hip Replacement Surgery for Traumatic Fractured Femoral Neck: A Retrospective Study |
| Q26799843 | Redox regulation of FoxO transcription factors |
| Q97419698 | Role of TNF-α and FGF-2 in the Fracture Healing Disorder of Type 2 Diabetes Model Induced by High Fat Diet Followed by Streptozotocin |
| Q55171215 | Role of Toll-Like Receptor 4 on Osteoblast Metabolism and Function. |
| Q35791713 | Role of forkhead transcription factors in diabetes-induced oxidative stress |
| Q35197731 | Smoking and impaired bone healing: will activation of cholinergic anti-inflammatory pathway be the bridge? |
| Q51737339 | Superior Potential of CD34-Positive Cells Compared to Total Mononuclear Cells for Healing of Nonunion Following Bone Fracture. |
| Q51326303 | Sustained, localized salicylic acid delivery enhances diabetic bone regeneration via prolonged mitigation of inflammation. |
| Q36981367 | Systemic inhibition of canonical Notch signaling results in sustained callus inflammation and alters multiple phases of fracture healing |
| Q42274273 | TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1. |
| Q54996755 | TNFα contributes to diabetes impaired angiogenesis in fracture healing. |
| Q58109102 | The Cellular Biology of Fracture Healing |
| Q92881718 | The Roles of FoxO Transcription Factors in Regulation of Bone Cells Function |
| Q27026032 | The adverse effects of diabetes on osteoarthritis: update on clinical evidence and molecular mechanisms |
| Q35683050 | The convergence of fracture repair and stem cells: interplay of genes, aging, environmental factors and disease |
| Q38488511 | The role of the microenvironment on the fate of adult stem cells |
| Q36395829 | Trauma-induced heterotopic bone formation and the role of the immune system: A review |
| Q26824702 | Tumor necrosis factor-induced cerebral insulin resistance in Alzheimer's disease links numerous treatment rationales |
| Q42486595 | Tumor necrosis factor-α and interleukin-6 expression in leukocytes and their association with polymorphisms and bone markers in diabetic individuals treated with pioglitazone. |
| Q47151037 | Tumor necrosis factor-α antagonist diminishes osteocytic RANKL and sclerostin expression in diabetes rats with periodontitis. |
| Q50198712 | Use of thiazolidinediones and risk of hip fracture in old people in a case-control study in Taiwan. |
| Q26777025 | Using mesenchymal stem cells as a therapy for bone regeneration and repairing |
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