Chondrocytes promote vascularization in fracture healing through a FOXO1 dependent mechanism

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Chondrocytes promote vascularization in fracture healing through a FOXO1 dependent mechanism is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JBMR.3610
P932PMC publication ID6414243
P698PubMed publication ID30347467

P2093author name stringDana T Graves
Chanyi Lu
J Patrick O'Connor
Citong Zhang
Mohammed Alharbi
Daniel Feinberg
Zhenjiang Ding
P2860cites workBlood vessel formation and function in boneQ26739893
Nestin: a novel angiogenesis marker and possible target for tumor angiogenesisQ26824035
FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasisQ28285131
The Phosphate Source Influences Gene Expression and Quality of Mineralization during In Vitro Osteogenic Differentiation of Human Mesenchymal Stem CellsQ28534068
FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in miceQ33645103
Osteochondral angiogenesis and increased protease inhibitor expression in OA.Q33882628
Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnoverQ34075040
Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization.Q34094624
FOXO1, TGF-β regulation and wound healingQ34359097
Impact of Diabetes on the Protective Role of FOXO1 in Wound HealingQ34476575
FoxO transcription factors support oxidative stress resistance in human chondrocytesQ34626746
Foxo1 inhibits diabetic mucosal wound healing but enhances healing of normoglycemic woundsQ34762513
Molecular mechanisms controlling bone formation during fracture healing and distraction osteogenesisQ35029178
Genetic inactivation of ERK1 and ERK2 in chondrocytes promotes bone growth and enlarges the spinal canalQ35097630
FOXO1 differentially regulates both normal and diabetic wound healingQ35543164
Angiogenesis and bone repairQ35595383
Role of forkhead transcription factors in diabetes-induced oxidative stressQ35791713
Application of histomorphometric methods to the study of bone repairQ36256721
Vascular biology and the skeletonQ36371220
Angiogenesis is required for stress fracture healing in ratsQ36442977
Osteoblast-derived VEGF regulates osteoblast differentiation and bone formation during bone repairQ36515058
Characterization of genetically engineered mouse models carrying Col2a1-cre-induced deletions of Lrp5 and/or Lrp6.Q36635388
Interleukin-1β induces fibroblast growth factor 2 expression and subsequently promotes endothelial progenitor cell angiogenesis in chondrocytes.Q36701444
The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivoQ36702566
Vasculopathy and disordered angiogenesis in selected rheumatic diseases: rheumatoid arthritis and systemic sclerosisQ36927749
FOXOs attenuate bone formation by suppressing Wnt signaling.Q37052939
Activation of the acquired immune response reduces coupled bone formation in response to a periodontal pathogenQ37089072
Differentiation of osteoblasts and osteocytes from mesenchymal stem cellsQ37161007
Glucosamine activates autophagy in vitro and in vivoQ37168084
Diabetes causes the accelerated loss of cartilage during fracture repair which is reversed by insulin treatment.Q37238865
FOXO1 promotes wound healing through the up-regulation of TGF-β1 and prevention of oxidative stressQ37267966
High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healingQ37362094
Dysregulated FOXO transcription factors in articular cartilage in aging and osteoarthritisQ37600074
The role of vascular endothelial growth factor in ossificationQ38020747
FOXO1 modulates osteoblast differentiationQ38337669
Cartilage to bone transformation during fracture healing is coordinated by the invading vasculature and induction of the core pluripotency genes.Q39016219
Regulation of vascular endothelial growth factor, VEGF, gene promoter by the tumor suppressor, WT1.Q40204188
The endothelium in psoriasis.Q40400542
TNF-alpha mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis through FOXO1.Q42274273
Vascular Endothelial Growth Factor in Cartilage Development and OsteoarthritisQ42375971
Vascular endothelial growth factor: an essential component of angiogenesis and fracture healingQ42917193
Angiogenesis is required for successful bone induction during distraction osteogenesisQ46738877
Earliest phases of chondrogenesis are dependent upon angiogenesis during ectopic bone formation in mice.Q50443765
Forkhead box O transcription factors in chondrocytes regulate endochondral bone formation.Q50574660
Core Binding Factor β Plays a Critical Role During Chondrocyte Differentiation.Q50583143
Disruption of Sirt1 in chondrocytes causes accelerated progression of osteoarthritis under mechanical stress and during ageing in mice.Q50948674
FoxO transcription factors modulate autophagy and proteoglycan 4 in cartilage homeostasis and osteoarthritis.Q51769136
Col2a1-directed expression of Cre recombinase in differentiating chondrocytes in transgenic mice.Q52169988
Lactoferrin inhibits the inflammatory and angiogenic activation of bovine aortic endothelial cells.Q54397089
FOXO1 Deletion Reverses the Effect of Diabetic-Induced Impaired Fracture HealingQ57045573
The splice variants VEGF121 and VEGF189 of the angiogenic peptide vascular endothelial growth factor are expressed in osteoarthritic cartilageQ73880328
Prevention of fracture healing in rats by an inhibitor of angiogenesisQ77308562
FOXO1 regulates VEGFA expression and promotes angiogenesis in healing woundsQ88161468
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)547-556
P577publication date2018-11-20
P1433published inJournal of Bone and Mineral ResearchQ15750941
P1476titleChondrocytes Promote Vascularization in Fracture Healing Through a FOXO1-Dependent Mechanism
P478volume34

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cites work (P2860)
Q92313879FOXO1 Mediates Advanced Glycation End Products Induced Mouse Osteocyte-Like MLO-Y4 Cell Apoptosis and Dysfunctions
Q92071841Mucosal Immunity and the FOXO1 Transcription Factors

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