| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M307853200 |
| P698 | PubMed publication ID | 12954613 |
| P50 | author | Michelle A Digman | Q62062552 |
| P2093 | author name string | Wonhwa Cho | |
| Robert V Stahelin | |||
| Bharath Ananthanarayanan | |||
| P2860 | cites work | The C2 domain calcium-binding motif: structural and functional diversity | Q24674621 |
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| P433 | issue | 47 | |
| P407 | language of work or name | English | Q1860 |
| P1104 | number of pages | 9 | |
| P304 | page(s) | 46886-46894 | |
| P577 | publication date | 2003-09-03 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains | |
| P478 | volume | 278 |
| Q39626922 | 1H, 13C and 15N NMR assignments of the C1A and C1B subdomains of PKC-delta |
| Q39857220 | A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon. |
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| Q34221941 | An ankyrin repeat domain of AKR2 drives chloroplast targeting through coincident binding of two chloroplast lipids. |
| Q40531200 | Autophosphorylation suppresses whereas kinase inhibition augments the translocation of protein kinase Calpha in response to diacylglycerol |
| Q38844327 | Biphasic Effect of Basic Fibroblast Growth Factor on Anterior Pituitary Folliculostellate TtT/GF Cell Coupling, and Connexin 43 Expression and Phosphorylation |
| Q37239601 | Cellular membranes and lipid-binding domains as attractive targets for drug development |
| Q36479386 | Cholesterol modulates cell signaling and protein networking by specifically interacting with PDZ domain-containing scaffold proteins |
| Q42625879 | Curcumin Inhibits Protein Kinase Cα Activity by Binding to Its C1 Domain |
| Q89601061 | DGKγ Knock-Out Mice Show Impairments in Cerebellar Motor Coordination, LTD, and the Dendritic Development of Purkinje Cells through the Activation of PKCγ |
| Q34360144 | Diacylglycerol-dependent binding recruits PKCtheta and RasGRP1 C1 domains to specific subcellular localizations in living T lymphocytes. |
| Q58006829 | Diacylglycerol-induced Membrane Targeting and Activation of Protein Kinase Cϵ |
| Q36069660 | Diacylglycerols as activators of protein kinase C. |
| Q40128306 | Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs |
| Q38268439 | Differential targeting of cPKC and nPKC decodes and regulates Ca²⁺ and lipid signalling |
| Q26799286 | Dynamics and Membrane Interactions of Protein Kinase C |
| Q44136854 | Gating of long-term depression by Ca2+/calmodulin-dependent protein kinase II through enhanced cGMP signalling in cerebellar Purkinje cells. |
| Q37305439 | High-throughput fluorescence assay for membrane-protein interaction |
| Q40098611 | Identification of acidic amino acid residues in the protein kinase C alpha V5 domain that contribute to its insensitivity to diacylglycerol |
| Q41176555 | Identification of an autoinhibitory mechanism that restricts C1 domain-mediated activation of the Rac-GAP alpha2-chimaerin |
| Q27683701 | Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ) |
| Q33307238 | Immunogold electron microscopic demonstration of distinct submembranous localization of the activated gammaPKC depending on the stimulation |
| Q80306441 | Importance of interaction between C1 domain and lipids in protein kinase C alpha activation: hydrophobic side chain direction in isobenzofuranone ligands controls enzyme activation level |
| Q33207528 | Inhibition of gap junction activity through the release of the C1B domain of protein kinase Cgamma (PKCgamma) from 14-3-3: identification of PKCgamma-binding sites |
| Q36853834 | Insight into intra- and inter-molecular interactions of PKC: design of specific modulators of kinase function |
| Q34074459 | Interactions of protein kinase C-α C1A and C1B domains with membranes: a combined computational and experimental study |
| Q42206669 | Interfacial partitioning of a loop hinge residue contributes to diacylglycerol affinity of conserved region 1 domains |
| Q45953801 | Kinetic analysis of the interaction of the C1 domain of protein kinase C with lipid membranes by stopped-flow spectroscopy. |
| Q43097544 | Lateral diffusion of peripheral membrane proteins on supported lipid bilayers is controlled by the additive frictional drags of (1) bound lipids and (2) protein domains penetrating into the bilayer hydrocarbon core |
| Q64108192 | Mass Spectrometric Imaging Reveals Temporal and Spatial Dynamics of Bioactive Lipids in Arteries Undergoing Restenosis |
| Q40563515 | Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta |
| Q50335802 | Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta |
| Q36772356 | Modeling Smith-Lemli-Opitz syndrome with induced pluripotent stem cells reveals a causal role for Wnt/β-catenin defects in neuronal cholesterol synthesis phenotypes |
| Q46231206 | Modeling studies on the structural determinants for the DAG/phorbol ester binding to C1 domain |
| Q42262277 | NFAT and NFkappaB activation in T lymphocytes: a model of differential activation of gene expression |
| Q45218831 | Oxidative activation of protein kinase Cgamma through the C1 domain. Effects on gap junctions |
| Q34534789 | PKC activation by resveratrol derivatives with unsaturated aliphatic chain |
| Q30480459 | PKCalpha: a versatile key for decoding the cellular calcium toolkit |
| Q41694250 | Phorbol esters dPPA/dPA promote furin expression involving transcription factor CEBPβ in neuronal cells. |
| Q36298326 | Phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) specifically induces membrane penetration and deformation by Bin/amphiphysin/Rvs (BAR) domains |
| Q34852542 | Phosphatidylinositol 4,5-bisphosphate decreases the concentration of Ca2+, phosphatidylserine and diacylglycerol required for protein kinase C α to reach maximum activity. |
| Q34712409 | Phosphatidylserine is a critical modulator for Akt activation |
| Q46757435 | Phosphoinositide specificity of and mechanism of lipid domain formation by annexin A2-p11 heterotetramer |
| Q34435861 | Phosphoinositides differentially regulate protrudin localization through the FYVE domain |
| Q29303618 | Phospholipase C in Living Cells |
| Q38846159 | Polyphenol compounds and PKC signaling |
| Q60340336 | ProLIF – quantitative integrin protein–protein interactions and synergistic membrane effects on proteoliposomes |
| Q33850659 | Probing the determinants of diacylglycerol binding affinity in the C1B domain of protein kinase Cα. |
| Q36744811 | Protein Kinase Cα (PKCα) Is Resistant to Long Term Desensitization/Down-regulation by Prolonged Diacylglycerol Stimulation |
| Q36003170 | Protein kinase C as a stress sensor |
| Q36073050 | Protein kinase C gamma mutations in the C1B domain cause caspase-3-linked apoptosis in lens epithelial cells through gap junctions |
| Q38116565 | Protein kinase C inhibitors: a patent review (2010 - present). |
| Q39701288 | Protein kinase C-alpha is expressed and activated during the development of renal cell carcinoma |
| Q51747393 | Protein kinase C-gamma activation in the early streptozotocin diabetic rat lens. |
| Q34407341 | Protein kinase Cgamma regulates myosin IIB phosphorylation, cellular localization, and filament assembly |
| Q36216413 | Protein kinase Cθ C2 domain is a phosphotyrosine binding module that plays a key role in its activation |
| Q36804642 | Quantitative properties and receptor reserve of the DAG and PKC branch of G(q)-coupled receptor signaling |
| Q40452410 | Reactive cysteine in the structural Zn(2+) site of the C1B domain from PKCα. |
| Q114674412 | Retracted Article: Synthesis of diacylglycerol analogs bearing photoaffinity tags for labelling mammalian diacylglycerol kinase |
| Q30575223 | Single-molecule studies reveal a hidden key step in the activation mechanism of membrane-bound protein kinase C-α |
| Q40344765 | Specific protein kinase C isoforms are required for rod photoreceptor differentiation. |
| Q54453781 | Structural and membrane binding analysis of the Phox homology domain of phosphoinositide 3-kinase-C2alpha. |
| Q33973406 | Structural basis of protein kinase C isoform function |
| Q54324884 | Synthesis and protein kinase C (PKC)-C1 domain binding properties of diacyltetrol based anionic lipids. |
| Q26799902 | Targeting Protein Kinase C Downstream of Growth Factor and Adhesion Signalling |
| Q30476704 | Targeting of protein kinase C-epsilon during Fcgamma receptor-dependent phagocytosis requires the epsilonC1B domain and phospholipase C-gamma1. |
| Q42503795 | The Role of Regulatory Domains in Maintaining Autoinhibition in the Multidomain Kinase PKCα. |
| Q45360576 | The fatty acid composition of diacylglycerols determines local signaling patterns |
| Q40389337 | The origin of C1A-C2 interdomain interactions in protein kinase Calpha. |
| Q48143510 | Toggling of Diacylglycerol Affinity Correlates with Conformational Plasticity in C1 Domains. |
| Q35734162 | Vitamin E isoforms directly bind PKCα and differentially regulate activation of PKCα. |
| Q92440771 | Water-soluble variant of human Lynx1 induces cell cycle arrest and apoptosis in lung cancer cells via modulation of α7 nicotinic acetylcholine receptors |
| Q47713707 | α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion. |
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