Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity.

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Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M008491200
P698PubMed publication ID11029472
P5875ResearchGate publication ID12295846

P50authorRobert V. StahelinQ54008523
Lenka BittovaQ64681969
P2093author name stringCho W
P2860cites workPhorbol ester binding to protein kinase C requires a cysteine-rich zinc-finger-like sequenceQ24612940
Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserineQ27620399
Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol esterQ27730271
Structure of the protein kinase Cbeta phospholipid-binding C2 domain complexed with Ca2+Q27766029
Protein kinase C: structure, function, and regulationQ28618608
Protein kinase C as a molecular machine for decoding calcium and diacylglycerol signalsQ28631532
Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cellsQ36274901
Mutagenesis of the C2 domain of protein kinase C-alpha. Differential roles of Ca2+ ligands and membrane binding residuesQ41028602
Regulation of protein kinase C.Q41382903
Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules.Q41549028
Regulation of protein kinase C betaII by its C2 domainQ42061325
Interaction of protein kinase C with phosphatidylserine. 2. Specificity and regulationQ43541326
Relation between various phospholipase actions on human red cell membranes and the interfacial phospholipid pressure in monolayersQ43568458
Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinitiesQ49103877
The C2 domain of the Ca(2+)-independent protein kinase C Apl II inhibits phorbol ester binding to the C1 domain in a phosphatidic acid-sensitive mannerQ57042798
Phosphoinositide-specific phospholipase C-delta 1 binds with high affinity to phospholipid vesicles containing phosphatidylinositol 4,5-bisphosphateQ67507881
Association of protein kinase C with phospholipid monolayers: two-stage irreversible bindingQ70412727
Kinetic analysis of macromolecular interactions using surface plasmon resonance biosensorsQ73025426
A phospholipase A2 kinetic and binding assay using phospholipid-coated hydrophobic beadsQ73538440
The C1 and C2 domains of protein kinase C are independent membrane targeting modules, with specificity for phosphatidylserine conferred by the C1 domainQ74311725
Differential membrane-binding and activation mechanisms of protein kinase C-alpha and -epsilonQ74429962
Interplay of C1 and C2 domains of protein kinase C-alpha in its membrane binding and activationQ77955215
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)4218-4226
P577publication date2000-10-11
P1433published inJournal of Biological ChemistryQ867727
P1476titleRoles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity
P478volume276

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cites work (P2860)
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