| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M507574200 |
| P698 | PubMed publication ID | 16243846 |
| P2093 | author name string | Lina M Obeid | |
| Wonhwa Cho | |||
| Robert V Stahelin | |||
| Zee-Yong Park | |||
| Jin-Hahn Kim | |||
| Jeong H Hwang | |||
| Korey R Johnson | |||
| P2860 | cites work | Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate | Q22010773 |
| Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform | Q22253469 | ||
| Cloning and characterization of a protein kinase A anchoring protein (AKAP)-related protein that interacts with and regulates sphingosine kinase 1 activity | Q24300119 | ||
| The nucleotide-binding site of human sphingosine kinase 1 | Q24312950 | ||
| Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine | Q27620399 | ||
| Contrasting membrane interaction mechanisms of AP180 N-terminal homology (ANTH) and epsin N-terminal homology (ENTH) domains | Q28203579 | ||
| Membrane targeting of C2 domains of phospholipase C-delta isoforms | Q28204978 | ||
| Identification and characterization of RPK118, a novel sphingosine kinase-1-binding protein | Q28206055 | ||
| Deamidation in human gamma S-crystallin from cataractous lenses is influenced by surface exposure | Q28208171 | ||
| PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA) | Q28215068 | ||
| Membrane-protein interactions in cell signaling and membrane trafficking | Q28248356 | ||
| Molecular cloning and functional characterization of murine sphingosine kinase | Q28281335 | ||
| Sphingosine 1-phosphate receptors | Q29013537 | ||
| Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway | Q29041393 | ||
| Sphingosine-1-phosphate: an enigmatic signalling lipid | Q29620563 | ||
| Sphingosine kinase-mediated Ca2+ signalling by G-protein-coupled receptors | Q32064388 | ||
| Role of the sphingosine-1-phosphate receptor EDG-1 in PDGF-induced cell motility | Q32075112 | ||
| Membrane targeting by C1 and C2 domains | Q34296902 | ||
| Sphingosine kinase 1 is an intracellular effector of phosphatidic acid | Q34341056 | ||
| Membrane binding assays for peripheral proteins. | Q34367949 | ||
| Effect of acidic phospholipids on sphingosine kinase | Q34389208 | ||
| Activation of sphingosine kinase 1 by ERK1/2-mediated phosphorylation | Q36267274 | ||
| Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival. | Q36294755 | ||
| Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta | Q40563515 | ||
| Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox | Q40674156 | ||
| The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2. | Q40676859 | ||
| Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity. | Q40849607 | ||
| Activation of sphingosine kinase by tumor necrosis factor-alpha inhibits apoptosis in human endothelial cells | Q40917265 | ||
| Mutagenesis of the C2 domain of protein kinase C-alpha. Differential roles of Ca2+ ligands and membrane binding residues | Q41028602 | ||
| Lateral pressure in membranes | Q41290982 | ||
| Use of surface plasmon resonance to probe the equilibrium and dynamic aspects of interactions between biological macromolecules. | Q41549028 | ||
| Regulatory effect of phorbol esters on sphingosine kinase in BALB/C 3T3 fibroblasts (variant A31): demonstration of cell type-specific response--a preliminary note | Q42802651 | ||
| Sphingosine-1-phosphate as second messenger in cell proliferation induced by PDGF and FCS mitogens | Q42805681 | ||
| Relation between various phospholipase actions on human red cell membranes and the interfacial phospholipid pressure in monolayers | Q43568458 | ||
| Differential roles of ionic, aliphatic, and aromatic residues in membrane-protein interactions: a surface plasmon resonance study on phospholipases A2. | Q43569366 | ||
| Mechanism of group IVA cytosolic phospholipase A(2) activation by phosphorylation | Q44529205 | ||
| A comparative study of the phase transitions of phospholipid bilayers and monolayers | Q45021086 | ||
| Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs. | Q52596156 | ||
| P433 | issue | 52 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | sphingosine 1-phosphate | Q418267 |
| P1104 | number of pages | 9 | |
| P304 | page(s) | 43030-43038 | |
| P577 | publication date | 2005-10-21 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The mechanism of membrane targeting of human sphingosine kinase 1. | |
| P478 | volume | 280 |
| Q34593159 | "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets |
| Q24306896 | A critical role for the protein phosphatase 2A B′α regulatory subunit in dephosphorylation of sphingosine kinase 1 |
| Q37255365 | Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells |
| Q36744076 | Aging bone marrow mesenchymal stromal cells have altered membrane glycerophospholipid composition and functionality |
| Q24628769 | An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown |
| Q40729905 | An active form of sphingosine kinase-1 is released in the extracellular medium as component of membrane vesicles shed by two human tumor cell lines. |
| Q33614412 | An autocrine sphingosine-1-phosphate signaling loop enhances NF-kappaB-activation and survival. |
| Q50078186 | An intrinsic lipid-binding interface controls sphingosine kinase 1 function |
| Q35268434 | An novel role of sphingosine kinase-1 (SPHK1) in the invasion and metastasis of esophageal carcinoma |
| Q51663836 | ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. |
| Q34488214 | Capitalizing on diversity: an integrative approach towards the multiplicity of cellular mechanisms underlying myogenic responsiveness |
| Q34505523 | Coupling between endocytosis and sphingosine kinase 1 recruitment. |
| Q36727413 | Cross-talk at the crossroads of sphingosine-1-phosphate, growth factors, and cytokine signaling |
| Q37391105 | Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. |
| Q40456885 | Deactivation of sphingosine kinase 1 by protein phosphatase 2A. |
| Q42458279 | Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain |
| Q39774569 | Enhancement of sphingosine kinase 1 catalytic activity by deletion of 21 amino acids from the COOH-terminus |
| Q39958771 | Filamin A links sphingosine kinase 1 and sphingosine-1-phosphate receptor 1 at lamellipodia to orchestrate cell migration |
| Q38307041 | Identification and characterization of a mirror-image oligonucleotide that binds and neutralizes sphingosine 1-phosphate, a central mediator of angiogenesis |
| Q50718278 | Insulin-like growth factors mediate heterotrimeric G protein-dependent ERK1/2 activation by transactivating sphingosine 1-phosphate receptors. |
| Q41694477 | Investigation of the Cell Surface Proteome of Human Periodontal Ligament Stem Cells. |
| Q37364679 | Involvement of sphingosine kinase in plant cell signalling |
| Q33784010 | Isoflurane via TGF-beta1 release increases caveolae formation and organizes sphingosine kinase signaling in renal proximal tubules |
| Q57457293 | Macrophage reprogramming by negatively charged membrane phospholipids controls infection |
| Q50335802 | Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta |
| Q57372579 | Membrane-permeable Calmodulin Inhibitors (e.g.W-7/W-13) Bind to Membranes, Changing the Electrostatic Surface Potential |
| Q36234717 | Oncogenic K-Ras regulates bioactive sphingolipids in a sphingosine kinase 1-dependent manner |
| Q36298326 | Phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) specifically induces membrane penetration and deformation by Bin/amphiphysin/Rvs (BAR) domains |
| Q35842095 | Phosphatidylserine binding is essential for plasma membrane recruitment and signaling function of 3-phosphoinositide-dependent kinase-1. |
| Q40617807 | Phosphatidylserine externalization and membrane blebbing are involved in the nonclassical export of FGF1 |
| Q34647336 | Phosphatidylserine in the brain: metabolism and function |
| Q38080394 | Protein-phospholipid interactions in nonclassical protein secretion: problem and methods of study. |
| Q36952890 | Ras nanoclusters: molecular structure and assembly |
| Q35988918 | Recruitment of sphingosine kinase to presynaptic terminals by a conserved muscarinic signaling pathway promotes neurotransmitter release |
| Q36715339 | Regulation and functional roles of sphingosine kinases |
| Q35683960 | Regulation of glucose and lipid homeostasis by adiponectin: effects on hepatocytes, pancreatic β cells and adipocytes |
| Q37960383 | Regulation of metabolism and transport of sphingosine-1-phosphate in mammalian cells |
| Q42283814 | Role of sphingosine kinase localization in sphingolipid signaling |
| Q36356934 | Shaping the landscape: metabolic regulation of S1P gradients |
| Q37344550 | Signaling at the membrane interface by the DGK/SK enzyme family |
| Q36307302 | SphK1 mediates hepatic inflammation in a mouse model of NASH induced by high saturated fat feeding and initiates proinflammatory signaling in hepatocytes |
| Q39095601 | Sphingolipids and glycerophospholipids - The "ying and yang" of lipotoxicity in metabolic diseases. |
| Q38809404 | Sphingolipids in mitochondria. |
| Q21296721 | Sphingolipids: a potential molecular approach to treat allergic inflammation |
| Q34121255 | Sphingosine 1-phosphate and cancer |
| Q33855307 | Sphingosine 1-phosphate and sphingosine kinase are involved in a novel signaling pathway leading to acrosomal exocytosis |
| Q38170107 | Sphingosine 1-phosphate axis: a new leader actor in skeletal muscle biology. |
| Q58748929 | Sphingosine Kinase Activates the Mitochondrial Unfolded Protein Response and Is Targeted to Mitochondria by Stress |
| Q29010971 | Sphingosine kinase 1 |
| Q35794452 | Sphingosine kinase 1 as an anticancer therapeutic target |
| Q39795101 | Sphingosine kinase 1 localized to the plasma membrane lipid raft microdomain overcomes serum deprivation induced growth inhibition |
| Q37610181 | Sphingosine kinase A is a pleiotropic and essential enzyme for Leishmania survival and virulence. |
| Q38177794 | Sphingosine kinase and sphingosine-1-phosphate: regulators in autoimmune and inflammatory disease |
| Q33886596 | Sphingosine kinase: Role in regulation of bioactive sphingolipid mediators in inflammation |
| Q35059057 | Sphingosine-1-phosphate acting via the S1P₁ receptor is a downstream signaling pathway in ceramide-induced hyperalgesia |
| Q38448843 | Sphingosine-1-phosphate metabolism: A structural perspective |
| Q37173184 | Sphingosine-1-phosphate: the Swiss army knife of sphingolipid signaling |
| Q37172893 | Targeting SphK1 as a new strategy against cancer |
| Q90642085 | Targeting Sphingosine Kinases for the Treatment of Cancer |
| Q36868420 | Targeting the sphingosine kinase/sphingosine 1-phosphate pathway in disease: review of sphingosine kinase inhibitors |
| Q46979613 | The calmodulin-binding site of sphingosine kinase and its role in agonist-dependent translocation of sphingosine kinase 1 to the plasma membrane |
| Q26997087 | The compartmentalization and translocation of the sphingosine kinases: mechanisms and functions in cell signaling and sphingolipid metabolism |
| Q40109540 | The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells. |
| Q37711953 | The role of sphingolipid signalling in diabetes‑associated pathologies (Review). |
| Q36415172 | The sphingosine and diacylglycerol kinase superfamily of signaling kinases: localization as a key to signaling function |
| Q49571965 | The unmasking of the lipid binding face of sphingosine kinase 1. |
| Q38915115 | Therapeutic Strategies and Pharmacological Tools Influencing S1P Signaling and Metabolism |
| Q37930972 | Therapeutic potential of targeting sphingosine kinase 1 in prostate cancer |
| Q24310414 | Translocation of sphingosine kinase 1 to the plasma membrane is mediated by calcium- and integrin-binding protein 1 |
| Q36724917 | Unraveling the complexities of sphingosine-1-phosphate function: the mast cell model |
| Q92818439 | WITHDRAWN: Ceramide and Sphingosine 1-Phosphate in adipose dysfunction |
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