| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M403191200 |
| P698 | PubMed publication ID | 15105418 |
| P50 | author | Michelle A Digman | Q62062552 |
| P2093 | author name string | Wonhwa Cho | |
| Robert V Stahelin | |||
| Martina Medkova | |||
| Bharath Ananthanarayanan | |||
| Heather R Melowic | |||
| John D Rafter | |||
| P2860 | cites work | Protein kinase C-delta is a negative regulator of antigen-induced mast cell degranulation | Q24537442 |
| The C2 domain calcium-binding motif: structural and functional diversity | Q24674621 | ||
| Spatial and temporal regulation of protein kinase D (PKD) | Q24678757 | ||
| Ca(2+) bridges the C2 membrane-binding domain of protein kinase Calpha directly to phosphatidylserine | Q27620399 | ||
| Structure of the C2 domain from novel protein kinase Cepsilon. A membrane binding model for Ca(2+)-independent C2 domains | Q27634333 | ||
| Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold | Q27729921 | ||
| Crystal structure of the cys2 activator-binding domain of protein kinase C delta in complex with phorbol ester | Q27730271 | ||
| Crystal structure of the C2 domain from protein kinase C-delta | Q27764892 | ||
| Roles of ionic residues of the C1 domain in protein kinase C-alpha activation and the origin of phosphatidylserine specificity. | Q40849607 | ||
| Protein kinase C. Seeing two domains | Q40935513 | ||
| Mutagenesis of the C2 domain of protein kinase C-alpha. Differential roles of Ca2+ ligands and membrane binding residues | Q41028602 | ||
| The catalytic domain of protein kinase C-delta in reciprocal delta and epsilon chimeras mediates phorbol ester-induced macrophage differentiation of mouse promyelocytes | Q41135284 | ||
| A structure-function study of the C2 domain of cytosolic phospholipase A2. Identification of essential calcium ligands and hydrophobic membrane binding residues. | Q42058981 | ||
| Phosphorylation of protein kinase Cdelta (PKCdelta) at threonine 505 is not a prerequisite for enzymatic activity. Expression of rat PKCdelta and an alanine 505 mutant in bacteria in a functional form | Q42062624 | ||
| Activation mechanisms of conventional protein kinase C isoforms are determined by the ligand affinity and conformational flexibility of their C1 domains | Q42447064 | ||
| Roles of calcium ions in the membrane binding of C2 domains. | Q43000381 | ||
| Role of hydrophobic residues in the C1b domain of protein kinase C delta on ligand and phospholipid interactions | Q43559695 | ||
| Differential roles of ionic, aliphatic, and aromatic residues in membrane-protein interactions: a surface plasmon resonance study on phospholipases A2. | Q43569366 | ||
| Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells | Q43764698 | ||
| Protein kinase Calpha contains two activator binding sites that bind phorbol esters and diacylglycerols with opposite affinities | Q49103877 | ||
| Recombinant C1b domain of PKCdelta triggers meiotic maturation upon microinjection in Xenopus laevis oocytes. | Q50722481 | ||
| Phosphatidylinositol 3-phosphate induces the membrane penetration of the FYVE domains of Vps27p and Hrs. | Q52596156 | ||
| Protein Kinase C δ Inhibits the Proliferation of Vascular Smooth Muscle Cells by Suppressing G1Cyclin Expression | Q58323667 | ||
| Site-directed mutagenesis by overlap extension using the polymerase chain reaction | Q27860503 | ||
| Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells | Q28189278 | ||
| Membrane targeting of C2 domains of phospholipase C-delta isoforms | Q28204978 | ||
| Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta | Q28504684 | ||
| Regulation of protein kinase C zeta by PI 3-kinase and PDK-1 | Q28567633 | ||
| Requirements of protein kinase cdelta for catalytic function. Role of glutamic acid 500 and autophosphorylation on serine 643 | Q28576984 | ||
| Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta | Q28580319 | ||
| Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis | Q28610843 | ||
| The proteolytic cleavage of protein kinase C isotypes, which generates kinase and regulatory fragments, correlates with Fas-mediated and 12-O-tetradecanoyl-phorbol-13-acetate-induced apoptosis | Q28610855 | ||
| Protein kinase C is regulated in vivo by three functionally distinct phosphorylations | Q28616082 | ||
| Regulation of conventional protein kinase C isozymes by phosphoinositide-dependent kinase 1 (PDK-1) | Q28616439 | ||
| Protein kinase C delta (PKC delta): activation mechanisms and functions | Q28616845 | ||
| C2-domains, structure and function of a universal Ca2+-binding domain | Q29619459 | ||
| Protein kinase C-delta C2-like domain is a binding site for actin and enables actin redistribution in neutrophils | Q30679049 | ||
| Differential localization of protein kinase C delta by phorbol esters and related compounds using a fusion protein with green fluorescent protein | Q30827671 | ||
| Multiple pathways control protein kinase C phosphorylation | Q33838086 | ||
| Membrane targeting by C1 and C2 domains | Q34296902 | ||
| Localization, anchoring, and functions of protein kinase C isozymes in the heart. | Q34299145 | ||
| Membrane binding assays for peripheral proteins. | Q34367949 | ||
| Nuclear import of PKCdelta is required for apoptosis: identification of a novel nuclear import sequence | Q34370159 | ||
| Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions | Q34466011 | ||
| Novel "nonkinase" phorbol ester receptors: the C1 domain connection | Q34568760 | ||
| Surface plasmon resonance spectroscopy: an emerging tool for the study of peptide-membrane interactions | Q34850080 | ||
| Move over protein kinase C, you've got company: alternative cellular effectors of diacylglycerol and phorbol esters. | Q34988000 | ||
| Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm | Q35031770 | ||
| Surface plasmon resonance spectroscopy in the study of membrane-mediated cell signalling | Q35083413 | ||
| Divergence and complexities in DAG signaling: looking beyond PKC | Q35579529 | ||
| Phosphorylation sites of protein kinase C delta in H2O2-treated cells and its activation by tyrosine kinase in vitro | Q36227862 | ||
| Tissue and cellular distribution of the extended family of protein kinase C isoenzymes | Q36531203 | ||
| Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies | Q37269275 | ||
| Low affinity binding of phorbol esters to protein kinase C and its recombinant cysteine-rich region in the absence of phospholipids | Q38294230 | ||
| Membrane translocation of novel protein kinase Cs is regulated by phosphorylation of the C2 domain | Q38306802 | ||
| Non-equivalent roles for the first and second zinc fingers of protein kinase Cdelta. Effect of their mutation on phorbol ester-induced translocation in NIH 3T3 cells | Q38354423 | ||
| Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox | Q40674156 | ||
| The molecular basis of differential subcellular localization of C2 domains of protein kinase C-alpha and group IVa cytosolic phospholipase A2. | Q40676859 | ||
| Molecular basis of the specific subcellular localization of the C2-like domain of 5-lipoxygenase | Q40756579 | ||
| Interaction of proteins with lipid headgroups: lessons from protein kinase C. | Q40832939 | ||
| P433 | issue | 28 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 29501-29512 | |
| P577 | publication date | 2004-04-22 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Cdelta | |
| P478 | volume | 279 |
| Q39626922 | 1H, 13C and 15N NMR assignments of the C1A and C1B subdomains of PKC-delta |
| Q30501409 | A cascade of protein kinase C isozymes promotes cytoskeletal polarization in T cells |
| Q39857220 | A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon. |
| Q24339085 | A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28 |
| Q42503419 | A single residue in the C1 domain sensitizes novel protein kinase C isoforms to cellular diacylglycerol production |
| Q37864977 | Accumulation of diacylglycerol in the Chlamydia inclusion vacuole: possible role in the inhibition of host cell apoptosis |
| Q42818619 | Ahnak protein activates protein kinase C (PKC) through dissociation of the PKC-protein phosphatase 2A complex |
| Q30494045 | Amot recognizes a juxtanuclear endocytic recycling compartment via a novel lipid binding domain |
| Q37239601 | Cellular membranes and lipid-binding domains as attractive targets for drug development |
| Q44928988 | Ceramide-1-phosphate binds group IVA cytosolic phospholipase a2 via a novel site in the C2 domain |
| Q37036491 | Characterization of the differential roles of the twin C1a and C1b domains of protein kinase C-delta |
| Q38919003 | Deleting the DAG kinase Dgk1 augments yeast vacuole fusion through increased Ypt7 activity and altered membrane fluidity. |
| Q58006829 | Diacylglycerol-induced Membrane Targeting and Activation of Protein Kinase Cϵ |
| Q40128306 | Differential membrane binding and diacylglycerol recognition by C1 domains of RasGRPs |
| Q42458279 | Differential roles of phosphatidylserine, PtdIns(4,5)P2, and PtdIns(3,4,5)P3 in plasma membrane targeting of C2 domains. Molecular dynamics simulation, membrane binding, and cell translocation studies of the PKCalpha C2 domain |
| Q38268439 | Differential targeting of cPKC and nPKC decodes and regulates Ca²⁺ and lipid signalling |
| Q26799286 | Dynamics and Membrane Interactions of Protein Kinase C |
| Q36213543 | Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors |
| Q36126593 | From lipid second messengers to molecular motors: microtubule-organizing center reorientation in T cells |
| Q34328014 | Identification and characterization of two functionally unknown genes involved in butanol tolerance of Clostridium acetobutylicum |
| Q36458611 | Identification of an alcohol binding site in the first cysteine-rich domain of protein kinase Cdelta |
| Q35063109 | Identification of novel anionic phospholipid binding domains in neutral sphingomyelinase 2 with selective binding preference |
| Q27683701 | Identification of the activator-binding residues in the second cysteine-rich regulatory domain of protein kinase Cθ (PKCθ) |
| Q35492502 | In situ quantitative imaging of cellular lipids using molecular sensors |
| Q34036130 | Increased membrane affinity of the C1 domain of protein kinase Cdelta compensates for the lack of involvement of its C2 domain in membrane recruitment |
| Q36853834 | Insight into intra- and inter-molecular interactions of PKC: design of specific modulators of kinase function |
| Q42206669 | Interfacial partitioning of a loop hinge residue contributes to diacylglycerol affinity of conserved region 1 domains |
| Q54210129 | Intestinal Epithelial Wnt Signaling Mediates Acetylcholine-Triggered Host Defense against Infection. |
| Q39606803 | Intramolecular conformational changes optimize protein kinase C signaling |
| Q45953801 | Kinetic analysis of the interaction of the C1 domain of protein kinase C with lipid membranes by stopped-flow spectroscopy. |
| Q37525124 | Lipid signaling on the mitochondrial surface |
| Q89761970 | Lipidomic Analysis of Cells and Extracellular Vesicles from High- and Low-Metastatic Triple-Negative Breast Cancer |
| Q36236148 | MARCKS protein mediates hydrogen peroxide regulation of endothelial permeability |
| Q50335802 | Mechanism of diacylglycerol-induced membrane targeting and activation of protein kinase Ctheta |
| Q42155934 | Mechanism of membrane redistribution of protein kinase C by its ATP-competitive inhibitors |
| Q24292965 | Mechanistic basis of differential cellular responses of phosphatidylinositol 3,4-bisphosphate- and phosphatidylinositol 3,4,5-trisphosphate-binding pleckstrin homology domains |
| Q38051634 | Microtubule-organizing center polarity and the immunological synapse: protein kinase C and beyond |
| Q38011499 | Mitochondria: signaling with phosphatidic acid |
| Q46231206 | Modeling studies on the structural determinants for the DAG/phorbol ester binding to C1 domain |
| Q35921737 | Molecular basis for failure of "atypical" C1 domain of Vav1 to bind diacylglycerol/phorbol ester |
| Q33581393 | Molecular basis of the potent membrane-remodeling activity of the epsin 1 N-terminal homology domain |
| Q38724298 | Orthogonal lipid sensors identify transbilayer asymmetry of plasma membrane cholesterol |
| Q37910359 | PKC-delta and PKC-epsilon: foes of the same family or strangers? |
| Q50292268 | PKC-delta is activated |
| Q50292266 | PKC-delta translocates to plasma membrane |
| Q36737539 | Phorbol 12-myristate 13-acetate-dependent protein kinase C delta-Tyr311 phosphorylation in cardiomyocyte caveolae |
| Q36298326 | Phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) specifically induces membrane penetration and deformation by Bin/amphiphysin/Rvs (BAR) domains |
| Q35842095 | Phosphatidylserine binding is essential for plasma membrane recruitment and signaling function of 3-phosphoinositide-dependent kinase-1. |
| Q46757435 | Phosphoinositide specificity of and mechanism of lipid domain formation by annexin A2-p11 heterotetramer |
| Q36804658 | Physiological role for phosphatidic acid in the translocation of the novel protein kinase C Apl II in Aplysia neurons |
| Q33850659 | Probing the determinants of diacylglycerol binding affinity in the C1B domain of protein kinase Cα. |
| Q36216413 | Protein kinase Cθ C2 domain is a phosphotyrosine binding module that plays a key role in its activation |
| Q34745605 | Regulation of phosphatidic Acid metabolism by sphingolipids in the central nervous system |
| Q46856695 | Regulation of protein kinase C delta by phorbol ester, endothelin-1, and platelet-derived growth factor in cardiac myocytes |
| Q114674412 | Retracted Article: Synthesis of diacylglycerol analogs bearing photoaffinity tags for labelling mammalian diacylglycerol kinase |
| Q35710950 | Star-PAP control of BIK expression and apoptosis is regulated by nuclear PIPKIα and PKCδ signaling. |
| Q54453781 | Structural and membrane binding analysis of the Phox homology domain of phosphoinositide 3-kinase-C2alpha. |
| Q33973406 | Structural basis of protein kinase C isoform function |
| Q42119485 | Structural bioinformatics prediction of membrane-binding proteins |
| Q47216307 | Structural determinants of phorbol ester binding activity of the C1a and C1b domains of protein kinase C theta. |
| Q54324884 | Synthesis and protein kinase C (PKC)-C1 domain binding properties of diacyltetrol based anionic lipids. |
| Q39004144 | Targeted activation of conventional and novel protein kinases C through differential translocation patterns |
| Q35516520 | The C2 Domain and Altered ATP-Binding Loop Phosphorylation at Ser³⁵⁹ Mediate the Redox-Dependent Increase in Protein Kinase C-δ Activity |
| Q40358838 | The mechanism of membrane targeting of human sphingosine kinase 1. |
| Q40389337 | The origin of C1A-C2 interdomain interactions in protein kinase Calpha. |
| Q38808973 | Tracking Diacylglycerol and Phosphatidic Acid Pools in Budding Yeast |
| Q98771710 | Tubular ER Associates With Diacylglycerol-Rich Structures During Lipid Droplet Consumption |
| Q41851995 | Tyrosine phosphorylation modifies protein kinase C delta-dependent phosphorylation of cardiac troponin I. |
| Q28511917 | Unique membrane interaction mode of group IIF phospholipase A2 |
| Q51476984 | Using Surface Plasmon Resonance to Quantitatively Assess Lipid-Protein Interactions. |
| Q46336206 | Visualizing the temporal effects of vasoconstrictors on PKC translocation and Ca2+ signaling in single resistance arterial smooth muscle cells |
| Q35734162 | Vitamin E isoforms directly bind PKCα and differentially regulate activation of PKCα. |
| Q33787261 | p23/Tmp21 differentially targets the Rac-GAP beta2-chimaerin and protein kinase C via their C1 domains |
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