Reduced expression of flavocytochrome b558, a component of the NADPH oxidase complex, in neutrophils from patients with myelodysplasia

scientific article published on September 2003

Reduced expression of flavocytochrome b558, a component of the NADPH oxidase complex, in neutrophils from patients with myelodysplasia is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0301-472X(03)00188-7
P698PubMed publication ID12962720
P5875ResearchGate publication ID10576619

P2093author name stringEdo Vellenga
Gwenny M Fuhler
A Lyndsay Drayer
Floris Hooijenga
P2860cites workHuman neutrophil immunodeficiency syndrome is associated with an inhibitory Rac2 mutationQ24678428
Proposals for the classification of the myelodysplastic syndromesQ28275931
The PX domains of p47phox and p40phox bind to lipid products of PI(3)KQ30016925
Mechanisms of expression of NADPH oxidase components in human cultured monocytes: role of cytokines and transcriptional regulators involvedQ32159886
Clinical and laboratory work-up of patients with neutrophil shortage or dysfunctionQ33807646
Current molecular models for NADPH oxidase regulation by Rac GTPaseQ34915029
Respiratory burst enzyme in human neutrophils. Evidence for multiple mechanisms of activationQ36996467
Location of the epitope for 7D5, a monoclonal antibody raised against human flavocytochrome b558, to the extracellular peptide portion of primate gp91phoxQ39611621
Neutrophils exposed to bacterial lipopolysaccharide upregulate NADPH oxidase assemblyQ39797688
Comparison of the roles of mitogen-activated protein kinase kinase and phosphatidylinositol 3-kinase signal transduction in neutrophil effector functionQ41848857
Alteration of c-mpl-mediated signal transduction in CD34(+) cells from patients with myelodysplastic syndromesQ42494430
Mitochondrial disruption and limited apoptosis of erythroblasts are associated with high risk myelodysplasia. An ultrastructural analysisQ43574401
The p40phox and p47phox PX domains of NADPH oxidase target cell membranes via direct and indirect recruitment by phosphoinositides.Q43812779
Granulocyte colony-stimulating factor primes NADPH oxidase in neutrophils through translocation of cytochrome b(558) by gelatinase-granule releaseQ44038889
Decreased phosphorylation of protein kinase B and extracellular signal-regulated kinase in neutrophils from patients with myelodysplasiaQ44279140
Phosphorylation of the respiratory burst oxidase subunit p47phox as determined by two-dimensional phosphopeptide mapping. Phosphorylation by protein kinase C, protein kinase A, and a mitogen-activated protein kinaseQ46600114
PtdIns(3)P regulates the neutrophil oxidase complex by binding to the PX domain of p40phoxQ57057849
Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1Q59053220
Superoxide anion production and expression of cytochrome b 558 by neutrophils are impaired in some patients with myelodysplastic syndromeQ68264521
An Improved Method for the Isolation of Eosinophilic Granulocytes From Peripheral Blood of Normal IndividualsQ68470048
The Rac target NADPH oxidase p67phox interacts preferentially with Rac2 rather than Rac1Q70870969
Superoxide release and NADPH oxidase components in mature human phagocytes: correlation between functional capacity and amount of functional proteinsQ71783579
Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on respiratory burst activity of neutrophiis in patients with myelodysplastic syndromesQ72069153
Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophilsQ72223341
Contribution of mitogen-activated protein kinase to stimulation of phospholipase D by the chemotactic peptide fMet-Leu-Phe in human neutrophilsQ73101558
The mitogen-activated protein kinase extracellular signal-regulated kinase 1/2 pathway is involved in formyl-methionyl-leucyl-phenylalanine-induced p47phox phosphorylation in human neutrophilsQ73112969
Decline in antibiotic enzyme activity of neutrophils is a prognostic factor for infections in patients with myelodysplastic syndromeQ73178110
Cytokine priming of the granulocyte respiratory burst in myelodysplastic syndromesQ73886842
Deficiency of neutrophilic granule membrane glycoproteins in the myelodysplastic syndromes: a common deficiency in 216 patients studied by the Cancer and Leukemia Group BQ73931509
Priming of the neutrophil respiratory burst involves p38 mitogen-activated protein kinase-dependent exocytosis of flavocytochrome b558-containing granulesQ74281351
Activation of mitogen-activated protein kinase cascades during priming of human neutrophils by TNF-alpha and GM-CSFQ77391774
P433issue9
P304page(s)752-759
P577publication date2003-09-01
P1433published inExperimental HematologyQ5421109
P1476titleReduced expression of flavocytochrome b558, a component of the NADPH oxidase complex, in neutrophils from patients with myelodysplasia
P478volume31

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cites work (P2860)
Q98952056Blood collection technique, anticoagulants and storing temperature have minor effects on the isolation of polymorphonuclear neutrophils
Q44859194Disturbed granulocyte macrophage-colony stimulating factor priming of phosphatidylinositol 3,4,5-trisphosphate accumulation and Rac activation in fMLP-stimulated neutrophils from patients with myelodysplasia
Q42231401Impact of human granulocyte and monocyte isolation procedures on functional studies
Q35075796Peripheral neutrophil functions and cell signalling in Crohn`s disease

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