| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0306-4522(01)00319-0 |
| P698 | PubMed publication ID | 11682157 |
| P2093 | author name string | Baldo BA | |
| Berridge CW | |||
| España RA | |||
| Kelley AE | |||
| P2860 | cites work | Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior | Q24315738 |
| Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR | Q24675425 | ||
| The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene | Q28142783 | ||
| A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains | Q28145391 | ||
| Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation | Q29615680 | ||
| Neurons containing hypocretin (orexin) project to multiple neuronal systems | Q29619641 | ||
| Orexin A activates locus coeruleus cell firing and increases arousal in the rat. | Q30504135 | ||
| Orexin A excites serotonergic neurons in the dorsal raphe nucleus of the rat. | Q31883018 | ||
| Effect of lateral cerebroventricular injection of the appetite-stimulating neuropeptide, orexin and neuropeptide Y, on the various behavioral activities of rats | Q33854221 | ||
| The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats | Q33892990 | ||
| Reduced number of hypocretin neurons in human narcolepsy | Q33923479 | ||
| Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems | Q34854732 | ||
| Impulse activity of locus coeruleus neurons in awake rats and monkeys is a function of sensory stimulation and arousal | Q36391168 | ||
| Actions of norepinephrine in the cerebral cortex and thalamus: implications for function of the central noradrenergic system | Q36721081 | ||
| ACTH-induced excessive grooming in the rat. | Q40084590 | ||
| The cerebral ventricles as the avenue for the dipsogenic action of intracranial angiotensin | Q40308233 | ||
| The neurobiology of narcolepsy-cataplexy | Q40802530 | ||
| Effects of locus coeruleus activation on electroencephalographic activity in neocortex and hippocampus. | Q41135416 | ||
| Neuronal activities in brain-stem cholinergic nuclei related to tonic activation processes in thalamocortical systems | Q41238674 | ||
| Distribution of orexin neurons in the adult rat brain | Q42471901 | ||
| Orexins stimulate corticosterone secretion of rat adrenocortical cells, through the activation of the adenylate cyclase-dependent signaling cascade | Q42481818 | ||
| Activation of ventrolateral preoptic neurons during sleep | Q42513216 | ||
| Nucleus basalis and thalamic control of neocortical activity in the freely moving rat. | Q42514091 | ||
| Differential sensitivity to the wake-promoting actions of norepinephrine within the medial preoptic area and the substantia innominata | Q43546304 | ||
| Effects of lateral preoptic area application of orexin-A on sleep-wakefulness | Q43830853 | ||
| Corticotropin-releasing factor acts via a third ventricle site to reduce exploratory behavior in rats | Q45169929 | ||
| Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons. | Q46210170 | ||
| Cellular bases of neocortical activation: modulation of neural oscillations by the nucleus basalis and endogenous acetylcholine | Q46267816 | ||
| Distribution and quantification of immunoreactive orexin A in rat tissues. | Q48112935 | ||
| Amphetamine acts within the medial basal forebrain to initiate and maintain alert waking | Q48120837 | ||
| CRF-induced excessive grooming behavior in rats and mice | Q48213236 | ||
| ACTH acts via an anterior ventral third ventricular site to elicit grooming behavior | Q48329119 | ||
| Distribution of orexin receptor mRNA in the rat brain | Q48347303 | ||
| Alpha adrenergic system in medial preoptic area involved in sleep-wakefulness in rats | Q48362649 | ||
| Regional study of cerebral ventricle sensitive sites to angiotensin II | Q48376353 | ||
| Different types of norepinephrinergic receptors are involved in preoptic area mediated independent modulation of sleep-wakefulness and body temperature | Q48431261 | ||
| Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups | Q48456064 | ||
| In vivo intrahippocampal microinfusion of carbachol and bicuculline induces theta-like oscillations in the septally deafferented hippocampus | Q48651372 | ||
| Effects on sleep and wakefulness of the injection of hypocretin-1 (orexin-A) into the laterodorsal tegmental nucleus of the cat. | Q48693700 | ||
| Enhancement of behavioral and electroencephalographic indices of waking following stimulation of noradrenergic beta-receptors within the medial septal region of the basal forebrain. | Q48884127 | ||
| Restraint-stress-induced changes in exploratory behavior appear to be mediated by norepinephrine-stimulated release of CRF. | Q48916358 | ||
| Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat. | Q49116076 | ||
| Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle | Q49162619 | ||
| Hypocretin (orexin) deficiency in human narcolepsy. | Q55033530 | ||
| Prefrontal cortical dopamine systems and the elaboration of functional corticostriatal circuits: implications for schizophrenia and Parkinson's disease | Q72222113 | ||
| Possible involvement of orexin in the stress reaction in rats | Q73585922 | ||
| Centrally administered orexin/hypocretin activates HPA axis in rats | Q73963341 | ||
| Cellular bases of hippocampal EEG in the behaving rat | Q105583587 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 699-715 | |
| P577 | publication date | 2001-01-01 | |
| P1433 | published in | Neuroscience | Q15708571 |
| P1476 | title | Wake-promoting and sleep-suppressing actions of hypocretin (orexin): basal forebrain sites of action | |
| P478 | volume | 106 |
| Q34384326 | A mathematical model towards understanding the mechanism of neuronal regulation of wake-NREMS-REMS states |
| Q34463599 | A proposed hypothalamic-thalamic-striatal axis for the integration of energy balance, arousal, and food reward |
| Q42852085 | Activation of orexin neurons through non-NMDA glutamate receptors evidenced by c-Fos immunohistochemistry |
| Q37342989 | Activation of orexin/hypocretin projections to basal forebrain and paraventricular thalamus by acute nicotine |
| Q37590372 | Activation of the basal forebrain by the orexin/hypocretin neurones. |
| Q35598409 | Activity, modulation and role of basal forebrain cholinergic neurons innervating the cerebral cortex |
| Q38215870 | Advances in the neurobiological bases for food 'liking' versus 'wanting'. |
| Q48460329 | Age-related decline in hypocretin (orexin) receptor 2 messenger RNA levels in the mouse brain. |
| Q34625292 | Age-related loss of orexin/hypocretin neurons. |
| Q35292045 | Aging-related alterations in orexin/hypocretin modulation of septo-hippocampal amino acid neurotransmission |
| Q50731361 | Amphetamine acts within the lateral hypothalamic area to elicit affectively neutral arousal and reinstate drug-seeking. |
| Q46094269 | Antagonism of orexin receptor-1 in the retrotrapezoid nucleus inhibits the ventilatory response to hypercapnia predominantly in wakefulness. |
| Q35104335 | Antagonistic interplay between hypocretin and leptin in the lateral hypothalamus regulates stress responses. |
| Q39135562 | Basal Forebrain Cholinergic System and Orexin Neurons: Effects on Attention |
| Q49989804 | Bmal1 knockdown suppresses wake and increases immobility without altering orexin A, corticotrophin-releasing hormone, or glutamate decarboxylase. |
| Q42015698 | Changes in brain orexin levels in a rat model of depression induced by neonatal administration of clomipramine |
| Q48558685 | Circadian-dependent and circadian-independent behavioral actions of hypocretin/orexin |
| Q37054916 | Complementary roles of orexin and melanin-concentrating hormone in feeding behavior. |
| Q24634619 | Control of sleep and wakefulness |
| Q36298136 | Current models and future directions for understanding the neural circuitries of maternal behaviors in rodents |
| Q30499169 | Delayed orexin signaling consolidates wakefulness and sleep: physiology and modeling |
| Q42503281 | Descending projections from the basal forebrain to the orexin neurons in mice. |
| Q46598680 | Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle. |
| Q100502191 | Dopamine transporter function fluctuates across sleep/wake state: potential impact for addiction |
| Q36956971 | Dual orexin actions on dorsal raphe and laterodorsal tegmentum neurons: noisy cation current activation and selective enhancement of Ca2+ transients mediated by L-type calcium channels |
| Q89619847 | Effects of Intranasal Orexin-A (Hypocretin-1) Administration on Neuronal Activation, Neurochemistry, and Attention in Aged Rats |
| Q41947724 | Effects of hypocretin (orexin) neuronal loss on sleep and extracellular adenosine levels in the rat basal forebrain |
| Q41115569 | Effects of rapid eye movement sleep deprivation on hypocretin neurons in the hypothalamus of a rat model of depression |
| Q26830022 | Energy expenditure: role of orexin |
| Q42446772 | Fos immunoreactivity in hypocretin-synthesizing and hypocretin-1 receptor-expressing neurons: effects of diurnal and nocturnal spontaneous waking, stress and hypocretin-1 administration |
| Q34990730 | Functions of the orexinergic/hypocretinergic system |
| Q45197349 | GABA-mediated control of hypocretin- but not melanin-concentrating hormone-immunoreactive neurones during sleep in rats |
| Q35534146 | Galanthamine plus estradiol treatment enhances cognitive performance in aged ovariectomized rats |
| Q48444350 | Ghrelin microinjection into forebrain sites induces wakefulness and feeding in rats. |
| Q42927248 | Glutamatergic lateral parabrachial neurons innervate orexin-containing hypothalamic neurons in the rat |
| Q35591448 | Highly specific role of hypocretin (orexin) neurons: differential activation as a function of diurnal phase, operant reinforcement versus operant avoidance and light level |
| Q38191600 | Hypocretin (orexin) regulation of sleep-to-wake transitions |
| Q35639591 | Hypocretin /orexin preferentially activates caudomedial ventral tegmental area dopamine neurons |
| Q34893412 | Hypocretin 1/orexin A in the ventral tegmental area enhances dopamine responses to cocaine and promotes cocaine self-administration |
| Q55442317 | Hypocretin as a Hub for Arousal and Motivation. |
| Q44115086 | Hypocretin increases impulse flow in the septohippocampal GABAergic pathway: implications for arousal via a mechanism of hippocampal disinhibition. |
| Q36525478 | Hypocretin receptor 1 blockade preferentially reduces high effort responding for cocaine without promoting sleep |
| Q41925736 | Hypocretin receptor 1 knockdown in the ventral tegmental area attenuates mesolimbic dopamine signaling and reduces motivation for cocaine |
| Q34277180 | Hypocretin-1 causes G protein activation and increases ACh release in rat pons. |
| Q24649135 | Hypocretin-1 dose-dependently modulates maternal behaviour in mice |
| Q37299612 | Hypocretin/Orexin neuropeptides: participation in the control of sleep-wakefulness cycle and energy homeostasis |
| Q35006072 | Hypocretin/Orexin regulation of dopamine signaling and cocaine self-administration is mediated predominantly by hypocretin receptor 1. |
| Q42469028 | Hypocretin/orexin antagonism enhances sleep-related adenosine and GABA neurotransmission in rat basal forebrain |
| Q37596060 | Hypocretin/orexin in arousal and stress |
| Q44835118 | Hypocretin/orexin innervation and excitation of identified septohippocampal cholinergic neurons. |
| Q38013859 | Hypocretin/orexin involvement in reward and reinforcement |
| Q52310246 | Hypocretin/orexin knock-out mice display disrupted behavioral and dopamine responses to cocaine. |
| Q36177962 | Hypocretin/orexin regulation of dopamine signaling: implications for reward and reinforcement mechanisms |
| Q46575698 | Hypocretin/orexin selectively increases dopamine efflux within the prefrontal cortex: involvement of the ventral tegmental area |
| Q34203591 | Hypocretin1/orexinA-immunoreactive axons form few synaptic contacts on rat ventral tegmental area neurons that project to the medial prefrontal cortex |
| Q36260008 | Hypocretins (orexins) and sleep-wake disorders |
| Q38027689 | Hypocretins and the neurobiology of sleep-wake mechanisms |
| Q39543910 | Identifying genes in monoamine nuclei that may determine stress vulnerability and depressive behavior in Wistar-Kyoto rats |
| Q36992168 | Inactivation of median preoptic nucleus causes c-Fos expression in hypocretin- and serotonin-containing neurons in anesthetized rat |
| Q42441383 | Inhibition of rostral basal forebrain neurons promotes wakefulness and induces FOS in orexin neurons |
| Q89178960 | Interaction between postpartum stage and litter age on maternal caregiving and medial preoptic area orexin |
| Q33875437 | Lateral Hypothalamic Control of the Ventral Tegmental Area: Reward Evaluation and the Driving of Motivated Behavior |
| Q27021825 | Lateral hypothalamus, nucleus accumbens, and ventral pallidum roles in eating and hunger: interactions between homeostatic and reward circuitry |
| Q42437760 | Modafinil increases histamine release in the anterior hypothalamus of rats |
| Q37762255 | Narcolepsy in Parkinson's disease |
| Q36541599 | Neural substrates of psychostimulant-induced arousal |
| Q34578843 | Neurobiological mechanisms for the regulation of mammalian sleep-wake behavior: reinterpretation of historical evidence and inclusion of contemporary cellular and molecular evidence |
| Q36531499 | Neuropeptides controlling energy balance: orexins and neuromedins |
| Q34518670 | Neuropharmacology of Sleep and Wakefulness |
| Q36393701 | Neuropharmacology of Sleep and Wakefulness: 2012 Update |
| Q37058637 | Noradrenergic modulation of arousal |
| Q28258629 | Noradrenergic modulation of wakefulness/arousal |
| Q33623396 | Optogenetic deconstruction of sleep-wake circuitry in the brain |
| Q42864406 | Optogenetic examination identifies a context-specific role for orexins/hypocretins in anxiety-related behavior. |
| Q38077489 | Orexin (hypocretin) receptor agonists and antagonists for treatment of sleep disorders. Rationale for development and current status |
| Q48374208 | Orexin A (hypocretin-1) application at the medial preoptic area potentiates male sexual behavior in rats. |
| Q36980393 | Orexin gene therapy restores the timing and maintenance of wakefulness in narcoleptic mice. |
| Q30498843 | Orexin receptor 2 expression in the posterior hypothalamus rescues sleepiness in narcoleptic mice |
| Q37413138 | Orexin receptor antagonists as therapeutic agents for insomnia |
| Q24597418 | Orexin receptors: pharmacology and therapeutic opportunities |
| Q39049017 | Orexin signaling in rostral lateral hypothalamus and nucleus accumbens shell in the control of spontaneous physical activity in high- and low-activity rats. |
| Q47892439 | Orexin stimulates breathing via medullary and spinal pathways |
| Q33643534 | Orexin/hypocretin modulation of the basal forebrain cholinergic system: Role in attention |
| Q42470987 | Organization of hypocretin/orexin efferents to locus coeruleus and basal forebrain arousal-related structures |
| Q42493362 | Organization of noradrenergic efferents to arousal-related basal forebrain structures |
| Q33188004 | Overlapping distributions of orexin/hypocretin- and dopamine-beta-hydroxylase immunoreactive fibers in rat brain regions mediating arousal, motivation, and stress |
| Q58913404 | Parkinson's disease and sleep/wake disturbances |
| Q34419745 | Projections of the suprachiasmatic nucleus and ventral subparaventricular zone in the Nile grass rat (Arvicanthis niloticus) |
| Q34607196 | Promotion of sleep by targeting the orexin system in rats, dogs and humans |
| Q57160068 | Recent advances in understanding the roles of hypocretin/orexin in arousal, affect, and motivation |
| Q34077418 | Regulation of cortical acetylcholine release: insights from in vivo microdialysis studies |
| Q26822482 | Regulation of zebrafish sleep and arousal states: current and prospective approaches |
| Q34040369 | Role of GPR30 in mediating estradiol effects on acetylcholine release in the hippocampus |
| Q27028141 | Role of orexin receptors in obesity: from cellular to behavioral evidence |
| Q28069502 | Role of the Orexin System on the Hypothalamus-Pituitary-Thyroid Axis |
| Q35000948 | Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitions |
| Q37897942 | Sleep neurobiology from a clinical perspective |
| Q57817996 | Sleep-Wake Cycling and Energy Conservation: Role of Hypocretin and the Lateral Hypothalamus in Dynamic State-Dependent Resource Optimization |
| Q48473912 | Sleep/wake fragmentation disrupts metabolism in a mouse model of narcolepsy |
| Q37695385 | State-dependent central chemoreception: a role of orexin |
| Q42723113 | Synaptic interactions between perifornical lateral hypothalamic area, locus coeruleus nucleus and the oral pontine reticular nucleus are implicated in the stage succession during sleep-wakefulness cycle |
| Q45941348 | Systemic and intrabasalis administration of the orexin-1 receptor antagonist, SB-334867, disrupts attentional performance in rats. |
| Q34502802 | The Neurobiology of Sleep and Wakefulness |
| Q37218734 | The brain hypocretins and their receptors: mediators of allostatic arousal. |
| Q37993422 | The cerebrospinal fluid: regulator of neurogenesis, behavior, and beyond |
| Q36587873 | The effect of clomipramine on wake/sleep and orexinergic expression in rats |
| Q33897435 | The hypocretin-orexin system regulates cocaine self-administration via actions on the mesolimbic dopamine system |
| Q52316130 | The hypocretin/orexin system as a target for excessive motivation in alcohol use disorders. |
| Q26830704 | The hypocretins/orexins: integrators of multiple physiological functions |
| Q34623823 | The hypocretins: setting the arousal threshold |
| Q55921579 | The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes |
| Q90463916 | The neurobiological basis of narcolepsy |
| Q35018717 | The role of hypocretin in driving arousal and goal-oriented behaviors. |
| Q34032576 | The tempted brain eats: pleasure and desire circuits in obesity and eating disorders |
| Q36003547 | The wake-promoting effects of hypocretin-1 are attenuated in old rats. |
| Q26795524 | Understanding how discrete populations of hypothalamic neurons orchestrate complicated behavioral states |
| Q40273091 | Upregulation of orexin/hypocretin expression in aged rats: Effects on feeding latency and neurotransmission in the insular cortex |
| Q42501076 | Vigilance state-dependent attenuation of hypercapnic chemoreflex and exaggerated sleep apnea in orexin knockout mice |
| Q48247851 | Wake-promoting actions of noradrenergic α1 - and β-receptors within the lateral hypothalamic area |
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