Physiology. Unfolding lipid metabolism

scientific article published on June 2008

Physiology. Unfolding lipid metabolism is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1126/SCIENCE.1159651
P8608Fatcat IDrelease_772wk3jtera75pepm35yy2d7qy
P932PMC publication ID2701207
P698PubMed publication ID18556540
P5875ResearchGate publication ID5299281

P2093author name stringJay D Horton
P2860cites workCoupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Q22011167
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPsQ24290776
Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletionQ24564683
IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein responseQ24672592
IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNAQ28214814
SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevationQ28365331
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetesQ28575190
An essential role in liver development for transcription factor XBP-1Q28593777
SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liverQ29547646
Mutant mammalian cells as tools to delineate the sterol regulatory element-binding protein pathway for feedback regulation of lipid synthesisQ34497858
Endoplasmic reticulum stress in health and diseaseQ36510035
Coordinate regulation of phospholipid biosynthesis and secretory pathway gene expression in XBP-1(S)-induced endoplasmic reticulum biogenesis.Q42832143
A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesisQ69907652
P433issue5882
P407language of work or nameEnglishQ1860
P304page(s)1433-1434
P577publication date2008-06-01
P1433published inScienceQ192864
P1476titlePhysiology. Unfolding lipid metabolism
P478volume320

Reverse relations

cites work (P2860)
Q35152201Different fatty acids inhibit apoB100 secretion by different pathways: unique roles for ER stress, ceramide, and autophagy
Q35186665Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance.
Q33952316Insulin-regulated Srebp-1c and Pck1 mRNA expression in primary hepatocytes from zucker fatty but not lean rats is affected by feeding conditions
Q42578244Old and rising stars in the lymphoid liver
Q43093620Protein targets of thioacetamide metabolites in rat hepatocytes
Q24303825Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation
Q36962066Roles of Vitamin A Metabolism in the Development of Hepatic Insulin Resistance.

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