| scholarly article | Q13442814 |
| P6179 | Dimensions Publication ID | 1023361329 |
| P356 | DOI | 10.1038/CDD.2011.136 |
| P932 | PMC publication ID | 3307979 |
| P698 | PubMed publication ID | 22015606 |
| P5875 | ResearchGate publication ID | 51732373 |
| P50 | author | Jerry E. Chipuk | Q38325376 |
| P2093 | author name string | G P Zambetti | |
| D C Phillips | |||
| J E Rehg | |||
| J R Jeffers | |||
| D R Green | |||
| J T Opferman | |||
| M J Parsons | |||
| S P Garrison | |||
| P2860 | cites work | BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program | Q38269004 |
| Influence of Bcl-2 family members on the cellular response of small-cell lung cancer cell lines to ABT-737. | Q40174205 | ||
| Growth factor modulation of p53-mediated growth arrest versus apoptosis | Q41365779 | ||
| Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death. | Q41808889 | ||
| Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis | Q41860419 | ||
| Apoptosis of leukocytes triggered by acute DNA damage promotes lymphoma formation | Q42033244 | ||
| The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized. | Q42064781 | ||
| FcepsilonRI aggregation promotes survival of connective tissue-like mast cells but not mucosal-like mast cells. | Q42509851 | ||
| Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors | Q46211824 | ||
| Assays to measure p53-dependent and -independent apoptosis. | Q53383173 | ||
| Mpl ligand prevents lethal myelosuppression by inhibiting p53-dependent apoptosis | Q74541750 | ||
| Hierarchical regulation of mitochondrion-dependent apoptosis by BCL-2 subfamilies | Q79370601 | ||
| Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak | Q24296478 | ||
| p53 has a direct apoptogenic role at the mitochondria | Q24298888 | ||
| Direct activation of Bax by p53 mediates mitochondrial membrane permeabilization and apoptosis | Q24307994 | ||
| The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells | Q24650702 | ||
| Puma cooperates with Bim, the rate-limiting BH3-only protein in cell death during lymphocyte development, in apoptosis induction | Q24677017 | ||
| BAX activation is initiated at a novel interaction site | Q27652635 | ||
| Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity | Q28138855 | ||
| Puma is an essential mediator of p53-dependent and -independent apoptotic pathways | Q28213279 | ||
| Apoptosis in the pathogenesis and treatment of disease | Q28235731 | ||
| Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis | Q28511080 | ||
| Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease | Q28513752 | ||
| The BCL-2 protein family: opposing activities that mediate cell death | Q29547380 | ||
| Blinded by the Light: The Growing Complexity of p53 | Q29547590 | ||
| An inhibitor of Bcl-2 family proteins induces regression of solid tumours | Q29547595 | ||
| BH3 domains of BH3-only proteins differentially regulate Bax-mediated mitochondrial membrane permeabilization both directly and indirectly | Q29617135 | ||
| Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics | Q29620467 | ||
| Deletion of Puma protects hematopoietic stem cells and confers long-term survival in response to high-dose gamma-irradiation. | Q33839818 | ||
| Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation | Q33931818 | ||
| Mitochondrial p53 activates Bak and causes disruption of a Bak-Mcl1 complex. | Q34312488 | ||
| Cytokine rescue of p53-dependent apoptosis and cell cycle arrest is mediated by distinct Jak kinase signaling pathways | Q35196865 | ||
| Selective regulation of Bcl-XL by a Jak kinase-dependent pathway is bypassed in murine hematopoietic malignancies | Q35207960 | ||
| The BCL-2 family reunion | Q35568029 | ||
| Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak. | Q36118156 | ||
| Life in the balance: how BH3-only proteins induce apoptosis. | Q36294226 | ||
| Selection against PUMA gene expression in Myc-driven B-cell lymphomagenesis | Q36846076 | ||
| Mechanism of apoptosis induction by inhibition of the anti-apoptotic BCL-2 proteins | Q37068553 | ||
| Living with death: the evolution of the mitochondrial pathway of apoptosis in animals. | Q37152726 | ||
| Bax activation by the BH3-only protein Puma promotes cell dependence on antiapoptotic Bcl-2 family members | Q37237621 | ||
| PUMA cooperates with direct activator proteins to promote mitochondrial outer membrane permeabilization and apoptosis | Q37571324 | ||
| P433 | issue | 4 | |
| P304 | page(s) | 642-649 | |
| P577 | publication date | 2011-10-21 | |
| P1433 | published in | Cell Death & Differentiation | Q2943974 |
| P1476 | title | Genetically defining the mechanism of Puma- and Bim-induced apoptosis | |
| P478 | volume | 19 |
| Q36531482 | 3p21.3 tumor suppressor gene RBM5 inhibits growth of human prostate cancer PC-3 cells through apoptosis |
| Q39222206 | Acidosis blocks CCAAT/enhancer-binding protein homologous protein (CHOP)- and c-Jun-mediated induction of p53-upregulated mediator of apoptosis (PUMA) during amino acid starvation |
| Q36178191 | Angiotensin II regulates activation of Bim via Rb/E2F1 during apoptosis: involvement of interaction between AMPKβ1/2 and Cdk4. |
| Q33769741 | Arsenic trioxide induces apoptosis in the THP1 cell line by downregulating EVI-1 |
| Q36907168 | Caspase-1 is a novel target of p63 in tumor suppression |
| Q28540934 | Cellular inhibitor of apoptosis (cIAP)-mediated ubiquitination of phosphofurin acidic cluster sorting protein 2 (PACS-2) negatively regulates tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) cytotoxicity |
| Q36234278 | Deregulation of Internal Ribosome Entry Site-Mediated p53 Translation in Cancer Cells with Defective p53 Response to DNA Damage |
| Q36343757 | Deubiquitinase USP9x confers radioresistance through stabilization of Mcl-1 |
| Q100750110 | Downregulation of PUMA underlies resistance to FGFR1 inhibitors in the stem cell leukemia/lymphoma syndrome |
| Q93343887 | EVI-1 modulates arsenic trioxide induced apoptosis through JNK signalling pathway in leukemia cells |
| Q38092837 | Getting away with murder: how does the BCL-2 family of proteins kill with immunity? |
| Q41964274 | Grand challenges in cell death and survival: apoptosis vs. necroptosis |
| Q52684406 | Induction of the p53 Tumor Suppressor in Cancer Cells through Inhibition of Cap-Dependent Translation. |
| Q43099640 | Mitochondrial shape governs BAX-induced membrane permeabilization and apoptosis. |
| Q37192687 | Multimodal interaction with BCL-2 family proteins underlies the proapoptotic activity of PUMA BH3 |
| Q38064995 | Nutrient availability links mitochondria, apoptosis, and obesity |
| Q37121933 | PUMA and BIM are required for oncogene inactivation-induced apoptosis. |
| Q40869003 | PUMA-mediated mitochondrial apoptotic disruption by hypoxic postconditioning |
| Q35955331 | Peritoneal expression of Matrilysin helps identify early post-operative recurrence of colorectal cancer. |
| Q38108321 | Role of p53 in Anticancer Drug Treatment- and Radiation-Induced Injury in Normal Small Intestine |
| Q35149652 | TAp73 promotes anabolism |
| Q39068205 | Targeting IRES-Mediated p53 Synthesis for Cancer Diagnosis and Therapeutics |
| Q38193997 | Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies? |
| Q42117299 | Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine |
| Q36882319 | p53 activation by Ni(II) is a HIF-1α independent response causing caspases 9/3-mediated apoptosis in human lung cells |
| Q33576855 | p63 transcriptionally regulates the expression of matrix metallopeptidase 13. |
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