Ezrin immunoreactivity is associated with increasing malignancy of astrocytic tumors but is absent in oligodendrogliomas

scientific article published on December 2000

Ezrin immunoreactivity is associated with increasing malignancy of astrocytic tumors but is absent in oligodendrogliomas is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0002-9440(10)64816-X
P932PMC publication ID1885782
P698PubMed publication ID11106550

P50authorAmin DerouicheQ42417783
P2093author name stringK D Geiger
W Schlote
P Stoldt
P2860cites workEzrin is a cyclic AMP-dependent protein kinase anchoring proteinQ24532065
Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2Q24676628
A new 82-kD barbed end-capping protein (radixin) localized in the cell-to-cell adherens junction: purification and characterizationQ24679495
cDNA cloning and sequencing of the protein-tyrosine kinase substrate, ezrin, reveals homology to band 4.1Q28261183
CD43 interacts with moesin and ezrin and regulates its redistribution to the uropods of T lymphocytes at the cell-cell contactsQ28272939
The ezrin protein family: membrane-cytoskeleton interactions and disease associationsQ30428648
The role of cytoskeleton in organizing growth cones: a microfilament-associated growth cone component depends upon microtubules for its localizationQ30442300
Glial fibrillary acidic protein and its fragments discriminate astrocytoma from oligodendrogliomaQ33178432
Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injuryQ34060749
ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transductionQ34414797
ERM proteins: head-to-tail regulation of actin-plasma membrane interactionQ34417697
Histological grading of gliomasQ35236928
Cytovillin, a microvillar Mr 75,000 protein. cDNA sequence, prokaryotic expression, and chromosomal localizationQ35887992
Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factorQ36219929
Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linkerQ36232246
Perturbation of cell adhesion and microvilli formation by antisense oligonucleotides to ERM family membersQ36534860
Essential functions of ezrin in maintenance of cell shape and lamellipodial extension in normal and transformed fibroblastsQ36880922
Microfilament Structure and Function in the Cortical CytoskeletonQ37132256
Prognostic value of tumour associated antigen immunoreactivity and apoptosis in cerebral glioblastomas: an analysis of 168 casesQ37228212
Analysis of proliferation and apoptosis in brain gliomas: prognostic and clinical valueQ38465603
Chemotherapy for brain tumorsQ38552090
Ezrin, a membrane-cytoskeletal linking protein, is involved in the process of invasion of endometrial cancer cellsQ40902115
ICAM-2 redistributed by ezrin as a target for killer cellsQ41183913
Cytokine regulation of ezrin expression in the human colon cancer cell line HT29.Q41222353
Deregulation of genes encoding microfilament-associated proteins during Fos-induced morphological transformationQ41371021
Ezrin: a protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structuresQ41640261
Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein familyQ42720142
Ezrin expression in stromal cells of capillary hemangioblastoma. An immunohistochemical survey of brain tumors.Q42827339
Ki-67 (clone MIB-1) proliferation index in recurrent glial neoplasms: no prognostic significanceQ45041801
Biochemical characterization of ezrin-actin interactionQ46069768
Apoptosis in astrocytomas with different grades of malignancyQ47744732
Three-dimensional analysis of dendritic spines. III. Glial sheathQ48554260
Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.Q55476212
Apoptosis and cell proliferation in human neuroepithelial tumors.Q55480555
Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cellsQ72572435
Mild familial neurofibromatosis 2 associates with expression of merlin with altered COOH-terminusQ73556119
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectoligodendrogliomaQ1318384
P304page(s)1785-1793
P577publication date2000-12-01
P1433published inThe American Journal of PathologyQ4744259
P1476titleEzrin immunoreactivity is associated with increasing malignancy of astrocytic tumors but is absent in oligodendrogliomas
P478volume157

Reverse relations

cites work (P2860)
Q34501518A functional association between merlin and HEI10, a cell cycle regulator.
Q40304710Abnormal ezrin localization is associated with clinicopathological features in invasive breast carcinomas
Q54610607Altered expression of ezrin in esophageal squamous cell carcinoma.
Q34112988Baicalein mediates inhibition of migration and invasiveness of skin carcinoma through Ezrin in A431 cells
Q40564974Co-operative effect of c-Src and ezrin in deregulation of cell-cell contacts and scattering of mammary carcinoma cells
Q42157104Correlation of in vitro infiltration with glioma histological type in organotypic brain slices
Q33532354Differential proteome analysis of human gliomas stratified for loss of heterozygosity on chromosomal arms 1p and 19q.
Q34495193ERM proteins and NF2 tumor suppressor: the Yin and Yang of cortical actin organization and cell growth signaling
Q33698044Epigenetic drugs can stimulate metastasis through enhanced expression of the pro-metastatic Ezrin gene
Q48416282Exposure to environmental enrichment prior to a cerebral cortex stab wound attenuates the postlesional astroglia response in rats
Q43636980Expression and functional significance of ezrin in human brain astrocytoma
Q37065917Ezrin Inhibition Up-regulates Stress Response Gene Expression
Q73739370Ezrin immunoreactivity in relation to survival in serous ovarian carcinoma patients
Q80844578Ezrin in primary cutaneous melanoma
Q39525953Ezrin is key regulator of Src-induced malignant phenotype in three-dimensional environment
Q39817880Ezrin overexpression in gastrointestinal stromal tumors: an independent adverse prognosticator associated with the non-gastric location
Q34187445Ezrin phosphorylation on tyrosine 477 regulates invasion and metastasis of breast cancer cells
Q34047483Ezrin promotes invasion and metastasis of pancreatic cancer cells
Q55474355Ezrin-dependent promotion of glioma cell clonogenicity, motility, and invasion mediated by BCL-2 and transforming growth factor-beta2.
Q55471650Galectin-3 as an immunohistochemical tool to distinguish pilocytic astrocytomas from diffuse astrocytomas, and glioblastomas from anaplastic oligodendrogliomas.
Q38153690Glutamine synthetase as an astrocytic marker: its cell type and vesicle localization
Q53086422Increase in ezrin expression from benign to malignant breast tumours.
Q28305905Increased expression of podoplanin in malignant astrocytic tumors as a novel molecular marker of malignant progression
Q55379731Mesenchymal stem cells enhance tumorigenic properties of human glioblastoma through independent cell-cell communication mechanisms.
Q38972375MicroRNA-204, a direct negative regulator of ezrin gene expression, inhibits glioma cell migration and invasion
Q47183915Molecular Determinants of Malignant Brain Cancers: From Intracellular Alterations to Invasion Mediated by Extracellular Vesicles
Q37218010Neuropathology and HIV dementia
Q39739259Overexpression of ezrin inactivates NF2 tumor suppressor in glioblastoma
Q77360855Peripheral astrocyte processes: monitoring by selective immunostaining for the actin-binding ERM proteins
Q92420947Perspectives for Ezrin and Radixin in Astrocytes: Kinases, Functions and Pathology
Q51805729Pleiotropic function of ezrin in human metastatic melanomas.
Q54422168Prognostic implication of ezrin overexpression in myxofibrosarcomas.
Q56993330Prognostic significance of immunohistochemical expression of ezrin in non-metastatic high-grade osteosarcoma
Q24656634Prognostic value of tumor microinvasion and metalloproteinases expression in intracranial pediatric ependymomas
Q48912859Proteomic analysis of oligodendrogliomas expressing a mutant isocitrate dehydrogenase-1.
Q31156673Screening differentially expressed genes in mouse hepatocarcinoma ascites cell line with high potential of lymphatic metastasis
Q39189513Silence of ezrin modifies migration and actin cytoskeleton rearrangements and enhances chemosensitivity of lung cancer cells in vitro
Q33943320Small molecule inhibitors of ezrin inhibit the invasive phenotype of osteosarcoma cells.
Q40476423Src phosphorylates ezrin at tyrosine 477 and induces a phosphospecific association between ezrin and a kelch-repeat protein family member.
Q55471244Stromal cells in hemangioblastoma: neuroectodermal differentiation and morphological similarities to ependymoma.
Q28582615Structural plasticity of perisynaptic astrocyte processes involves ezrin and metabotropic glutamate receptors.
Q35197224Subcellular distribution and expression of cofilin and ezrin in human colon adenocarcinoma cell lines with different metastatic potential
Q38165795Systematic review of protein biomarkers of invasive behavior in glioblastoma
Q64907768The Cytoskeleton-A Complex Interacting Meshwork.
Q30651861The Prognostic Role of Ezrin Immunoexpression in Osteosarcoma: A Meta-Analysis of Published Data
Q24810263The membrane cytoskeletal crosslinker ezrin is required for metastasis of breast carcinoma cells
Q39904552The role of the membrane cytoskeleton cross-linker ezrin in medulloblastoma cells
Q37263471Two cases of primary malignant fibrous histiocytoma of the liver: immunohistochemical expression of ezrin and its relationship with prognosis
Q36179753Upregulated expression of Ezrin and invasive phenotype in malignantly transformed esophageal epithelial cells
Q35005380ß1 integrin binding phosphorylates ezrin at T567 to activate a lipid raft signalsome driving invadopodia activity and invasion

Search more.