Phenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice.

scientific article published on October 2010

Phenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S00418-010-0747-1
P698PubMed publication ID20886225

P50authorSeddik HammadQ42872147
Jan G HengstlerQ49800573
P2093author name stringPatricio Godoy
Dirk Drasdo
Albert Braeuning
Michael Schwarz
Albrecht Buchmann
Stefan Hoehme
Benjamin Rignall
Yasmin Singh
Amnah Othman
Iris von Recklinghausen
P2860cites workA new mathematical model for relative quantification in real-time RT-PCRQ27860781
beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skinQ28190343
Apc tumor suppressor gene is the "zonation-keeper" of mouse liverQ28589915
Liver-targeted disruption of Apc in mice activates beta-catenin signaling and leads to hepatocellular carcinomasQ28592004
Hepatocellular carcinoma pathogenesis: from genes to environmentQ29615767
Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regenerationQ30495068
Lack of phenobarbital-mediated promotion of hepatocarcinogenesis in connexin32-null mice.Q31443692
Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesisQ35197463
Metabolic zonation of the liver: regulation and implications for liver functionQ35417325
Focus on hepatocellular carcinoma.Q35721877
Evidence that interaction of hepatocytes with the collecting (hepatic) veins triggers position-specific transcription of the glutamine synthetase and ornithine aminotransferase genes in the mouse liverQ36743544
WNT/beta-catenin signaling in liver health and diseaseQ36804161
Roles of gap junctions and connexins in non-neoplastic pathological processes in which cell proliferation is involved.Q36892230
Wnt/beta-catenin pathway in hepatocellular carcinoma pathogenesis and liver physiology.Q37298654
beta-Catenin as a multilayer modulator of zonal cytochrome P450 expression in mouse liverQ37661567
Wnt/beta-catenin signaling activates and determines hepatic zonal expression of glutathione S-transferases in mouse liverQ38346810
Functional specialization of different hepatocyte populationsQ38663205
The RL-ET-14 cell line mediates expression of glutamine synthetase through the upstream enhancer/promoter region.Q40426377
Zonation of metabolism and gene expression in liver.Q40459673
Glutamine synthetase and hepatocarcinogenesisQ40459807
Zonation of parenchymal and nonparenchymal metabolism in liverQ41138372
Zonation of cytochrome P450 expression, drug metabolism and toxicity in liverQ41333879
Heterogeneous distribution of glutamine synthetase among rat liver parenchymal cells in situ and in primary culture.Q41449098
Cell-cell interactions in the regulation of the expression of hepatic enzymes.Q41594522
Zonation of hepatic cytochrome P-450 expression and regulationQ41665962
Induction of glutamine synthetase in periportal hepatocytes by cocultivation with a liver epithelial cell lineQ41720553
Beta-catenin: a key mediator of Wnt signalingQ41732761
Conditional beta-catenin loss in mice promotes chemical hepatocarcinogenesis: role of oxidative stress and platelet-derived growth factor receptor alpha/phosphoinositide 3-kinase signaling.Q42067728
Inducibility of drug-metabolizing enzymes by xenobiotics in mice with liver-specific knockout of Ctnnb1.Q42449884
Conditional deletion of beta-catenin reveals its role in liver growth and regenerationQ42504022
Selective pressure during tumor promotion by phenobarbital leads to clonal outgrowth of beta-catenin-mutated mouse liver tumorsQ43831008
Overexpression of glutamine synthetase is associated with beta-catenin-mutations in mouse liver tumors during promotion of hepatocarcinogenesis by phenobarbital.Q44183092
New targets of beta-catenin signaling in the liver are involved in the glutamine metabolismQ44226601
A beta-catenin-dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumorsQ45096299
Liver-specific loss of beta-catenin blocks glutamine synthesis pathway activity and cytochrome p450 expression in miceQ46224632
Tumor promotion in liver of mice with a conditional Cx26 knockoutQ46727133
Zonal gene expression in murine liver: lessons from tumorsQ46959089
Fate of extrahepatic human stem and precursor cells after transplantation into mouse livers.Q48906218
Extracellular matrix modulates sensitivity of hepatocytes to fibroblastoid dedifferentiation and transforming growth factor beta-induced apoptosis.Q51775502
Expression of gap junction protein connexin32 in chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.Q51990803
Lack of tumorigenesis in the mouse liver after adenovirus-mediated expression of a dominant stable mutant of beta-catenin.Q53391138
Hepatocarcinogenesis in mice with beta-catenin and Ha-ras gene mutationsQ64379604
Reestablishment of the heterogeneous distribution of hepatic glutamine synthetase during regeneration after CCl4-intoxicationQ68090097
Periportal and perivenous hepatocytes retain their zonal characteristics in primary cultureQ70150169
Position-specific gene expression in the liver lobule is directed by the microenvironment and not by the previous cell differentiation stateQ77801036
Zonal gene expression in mouse liver resembles expression patterns of Ha-ras and beta-catenin mutated hepatomasQ79551069
Liver-specific loss of beta-catenin results in delayed hepatocyte proliferation after partial hepatectomyQ79671125
PCB 153, a non-dioxin-like tumor promoter, selects for beta-catenin (Catnb)-mutated mouse liver tumorsQ79748085
Zonal expression of hepatocytic marker enzymes during liver repopulationQ80494884
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)469-481
P577publication date2010-10-01
P1433published inHistochemistry and Cell BiologyQ1524012
P1476titlePhenotype and growth behavior of residual β-catenin-positive hepatocytes in livers of β-catenin-deficient mice
P478volume134

Reverse relations

cites work (P2860)
Q46907265A frequent misinterpretation in current research on liver fibrosis: the vessel in the center of CCl4-induced pseudolobules is a portal vein
Q41777442A novel role of nucleostemin in maintaining the genome integrity of dividing hepatocytes during mouse liver development and regeneration
Q39336968Advances in 2D and 3D in vitro systems for hepatotoxicity testing
Q90641023Amniotic mesenchymal stem cells derived hepatocyte-like cells attenuated liver fibrosis more efficiently by mixed-cell transplantation
Q46166158Creation of Three-Dimensional Liver Tissue Models from Experimental Images for Systems Medicine.
Q35546735Depletion of β-catenin from mature hepatocytes of mice promotes expansion of hepatic progenitor cells and tumor development
Q42731617Gender-specific interplay of signaling through β-catenin and CAR in the regulation of xenobiotic-induced hepatocyte proliferation.
Q41870215Genetic ablation of β-catenin inhibits the proliferative phenotype of mouse liver adenomas
Q46359928Hepatocellular cancer
Q39297334Hepatocyte γ-catenin compensates for conditionally deleted β-catenin at adherens junctions
Q41774035Highlight report: Software for tissue analysis and reconstruction.
Q37833524Histochemistry and cell biology: the annual review 2010.
Q52853229Is the question of phenobarbital as potential liver cancer risk factor for humans really resolved?
Q39356585Pericentral activity of alpha-fetoprotein enhancer 3 and glutamine synthetase upstream enhancer in the adult liver are regulated by β-catenin in mice.
Q46889611Phenobarbital-mediated tumor promotion in transgenic mice with humanized CAR and PXR.
Q84711004Phenotype of single hepatocytes expressing an activated version of β-catenin in liver of transgenic mice
Q30442295Postnatal development, maturation and aging in the mouse cochlea and their effects on hair cell regeneration
Q37717919Protocols for staining of bile canalicular and sinusoidal networks of human, mouse and pig livers, three-dimensional reconstruction and quantification of tissue microarchitecture by image processing and analysis
Q41966844Quantification of three-dimensional structures in liver tissue: bile canalicular and sinusoidal networks
Q37121662Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME.
Q44039549Selective poisoning of Ctnnb1-mutated hepatoma cells in mouse liver tumors by a single application of acetaminophen
Q38879910Signal integration by the CYP1A1 promoter--a quantitative study
Q38601609Spontaneous repopulation of β-catenin null livers with β-catenin-positive hepatocytes after chronic murine liver injury
Q42837606Tumor formation in liver of conditional -catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen
Q40030443Tumor promotion and inhibition by phenobarbital in livers of conditional Apc-deficient mice
Q91643281Wnt signaling in liver disease: emerging trends from a bibliometric perspective

Search more.