scholarly article | Q13442814 |
P50 | author | Anthony Maxwell | Q37380949 |
Manlio Palumbo | Q39519418 | ||
P2093 | author name string | L A Mitchenall | |
E Vazquez | |||
C Sissi | |||
A Chemello | |||
P2860 | cites work | Structural insight into the quinolone-DNA cleavage complex of type IIA topoisomerases | Q27655501 |
A crystal structure of the bifunctional antibiotic simocyclinone D8, bound to DNA gyrase | Q27658456 | ||
DNA gyrase as a drug target | Q28139769 | ||
The ATP-binding site of type II topoisomerases as a target for antibacterial drugs | Q28207771 | ||
The interaction between coumarin drugs and DNA gyrase | Q28256018 | ||
Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040. | Q31096529 | ||
DNA gyrase: an enzyme that introduces superhelical turns into DNA | Q34013173 | ||
The interaction of drugs with DNA gyrase: a model for the molecular basis of quinolone action | Q34092838 | ||
The fluoroquinolone antibacterials: past, present and future perspectives | Q34143393 | ||
DNA gyrase: structure and function. | Q34507230 | ||
Mechanism of action of nalidixic acid: Purification of Escherichia coli nalA gene product and its relationship to DNA gyrase and a novel nicking-closing enzyme | Q35059616 | ||
Energy coupling in DNA gyrase and the mechanism of action of novobiocin | Q35994466 | ||
Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II. | Q36136076 | ||
Thirty years of Escherichia coli DNA gyrase: from in vivo function to single-molecule mechanism. | Q36775907 | ||
Discovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents | Q36907300 | ||
Quinolone-mediated bacterial death. | Q36921143 | ||
Antimicrobial resistance in hospitals: how concerned should we be? | Q37088893 | ||
In vivo and in vitro patterns of the activity of simocyclinone D8, an angucyclinone antibiotic from Streptomyces antibioticus | Q37190713 | ||
DNA topoisomerases: harnessing and constraining energy to govern chromosome topology | Q37255381 | ||
Therapeutic challenges in the era of antibiotic resistance | Q37365771 | ||
What's new on the antimicrobial horizon? | Q37365775 | ||
DNA Gyrase and DNA Supercoiling | Q40251916 | ||
The nature of inhibition of DNA gyrase by the coumarins and the cyclothialidines revealed by X-ray crystallography | Q41064279 | ||
Simocyclinone D8, an inhibitor of DNA gyrase with a novel mode of action | Q41093787 | ||
Ciprofloxacin affects conformational equilibria of DNA gyrase A in the presence of magnesium ions | Q43685586 | ||
Sites of reaction of Escherichia coli DNA gyrase on pBR322 in vivo as revealed by oxolinic acid-induced plasmid linearization | Q43785093 | ||
Simocyclinones, novel cytostatic angucyclinone antibiotics produced by Streptomyces antibioticus Tü 6040 II. Structure elucidation and biosynthesis | Q43996029 | ||
The role of GyrB in the DNA cleavage-religation reaction of DNA gyrase: a proposed two metal-ion mechanism | Q44019092 | ||
Simocyclinones, novel cytostatic angucyclinone antibiotics produced by Streptomyces antibioticus Tü 6040. I. Taxonomy, fermentation, isolation and biological activities | Q48744539 | ||
The 43-kilodalton N-terminal fragment of the DNA gyrase B protein hydrolyzes ATP and binds coumarin drugs. | Q52399144 | ||
DNA gyrase requires DNA for effective two-site coordination of divalent metal ions: further insight into the mechanism of enzyme action. | Q53464975 | ||
Conformational changes in DNA gyrase revealed by limited proteolysis. | Q53947449 | ||
Nucleotide binding to the 43-kilodalton N-terminal fragment of the DNA gyrase B protein. | Q54607440 | ||
The Effects of Metal Ions on the Structure and Stability of the DNA Gyrase B Protein | Q59694958 | ||
The Interaction of Coumarin Antibiotics with Fragments of the DNA Gyrase B Protein† | Q59695045 | ||
Domain Structure of Escherichia coli DNA Gyrase As Revealed by Differential Scanning Calorimetry | Q59695058 | ||
On the mechanism of action of quinolone drugs | Q60710070 | ||
Microbial growth and production kinetics of Streptomyces antibioticus Tü 6040 | Q73956986 | ||
Simocyclinones, Novel Cytostatic Angucyclinone Antibiotics Produced by Streptomyces antibioticus Tue 6040. II. Structure Elucidation and Biosynthesis. | Q78429069 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 213-220 | |
P577 | publication date | 2009-10-26 | |
P1433 | published in | Antimicrobial Agents and Chemotherapy | Q578004 |
P1476 | title | Mapping simocyclinone D8 interaction with DNA gyrase: evidence for a new binding site on GyrB. | |
P478 | volume | 54 |
Q27681978 | A New Crystal Structure of the Bifunctional Antibiotic Simocyclinone D8 Bound to DNA Gyrase Gives Fresh Insight into the Mechanism of Inhibition |
Q35791501 | Architecture and conservation of the bacterial DNA replication machinery, an underexploited drug target |
Q34214929 | Exploiting bacterial DNA gyrase as a drug target: current state and perspectives. |
Q28828721 | Identification of novel bacterial DNA gyrase inhibitors: An in silico study |
Q37694351 | In front of and behind the replication fork: bacterial type IIA topoisomerases. |
Q36158288 | Protective effect of Qnr on agents other than quinolones that target DNA gyrase |
Q35680284 | SimReg1 is a master switch for biosynthesis and export of simocyclinone D8 and its precursors |
Q46263843 | Structural insights into simocyclinone as an antibiotic, effector ligand, and substrate |
Q49832269 | Topoisomerases as anticancer targets |
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