Discovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents

scientific article published on January 2007

Discovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.2174/092986707781368414
P698PubMed publication ID17691945
P5875ResearchGate publication ID6147531

P2093author name stringMiha Kotnik
Tom Solmajer
Marko Oblak
P433issue19
P304page(s)2033-2047
P577publication date2007-01-01
P1433published inCurrent Medicinal ChemistryQ3007710
P1476titleDiscovery and development of ATPase inhibitors of DNA gyrase as antibacterial agents
P478volume14

Reverse relations

cites work (P2860)
Q33796345A high-throughput fluorescence polarization assay for inhibitors of gyrase B
Q35791501Architecture and conservation of the bacterial DNA replication machinery, an underexploited drug target
Q37998090Bacterial DNA replication enzymes as targets for antibacterial drug discovery
Q33398170Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue
Q33793074Challenges of antibacterial discovery
Q28284744DNA topoisomerases and their poisoning by anticancer and antibacterial drugs
Q35815665Discovery of Indazole Derivatives as a Novel Class of Bacterial Gyrase B Inhibitors
Q34095957Evaluating the genotoxicity of topoisomerase-targeted antibiotics
Q43473553Evaluation of WO2012177707 and WO2012097269: Vertex's phosphate prodrugs of gyrase and topoisomerase antibacterial agents
Q34214929Exploiting bacterial DNA gyrase as a drug target: current state and perspectives.
Q93083428Identification of an auxiliary druggable pocket in the DNA gyrase ATPase domain using fragment probes
Q37694351In front of and behind the replication fork: bacterial type IIA topoisomerases.
Q54358881Inhibition of DNA gyrase and DNA topoisomerase IV of Staphylococcus aureus and Escherichia coli by aminocoumarin antibiotics.
Q94548290Lead Identification of 8-(Methylamino)-2-oxo-1,2-dihydroquinoline Derivatives as DNA Gyrase Inhibitors: Hit-to-Lead Generation Involving Thermodynamic Evaluation
Q42947154Mapping simocyclinone D8 interaction with DNA gyrase: evidence for a new binding site on GyrB.
Q38068475Multitarget ligands in antibacterial research: progress and opportunities
Q57265865New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity
Q42249570Novel phytochemical-antibiotic conjugates as multitarget inhibitors of Pseudomononas aeruginosa GyrB/ParE and DHFR.
Q51713941Quantitative structure-activity relationship study of antitubercular fluoroquinolones.
Q82816075Schiff bases of indoline-2,3-dione: potential novel inhibitors of Mycobacterium tuberculosis (Mtb) DNA gyrase
Q27675559Structural–Functional Studies of Burkholderia cenocepacia d -Glycero-β- d -manno-heptose 7-Phosphate Kinase (HldA) and Characterization of Inhibitors with Antibiotic Adjuvant and Antivirulence Properties
Q48175813Synthesis and Evaluation of N-Phenylpyrrolamides as DNA Gyrase B Inhibitors
Q37612256Syringa oblata Lindl. Aqueous Extract Is a Potential Biofilm Inhibitor in S. suis
Q35872631Targeting druggable enzymome by exploiting natural medicines: An in silico-in vitro integrated approach to combating multidrug resistance in bacterial infection
Q43221173The challenge of developing robust drugs to overcome resistance
Q45717201Thermodynamic computational approach to capture molecular recognition in the binding of different inhibitors to the DNA gyrase B subunit from Escherichia coli
Q28538023Tricyclic GyrB/ParE (TriBE) inhibitors: a new class of broad-spectrum dual-targeting antibacterial agents
Q42710319Tricyclic sesquiterpenes from Vetiveria zizanoides (L.) Nash as antimycobacterial agents

Search more.