Regulation of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal

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Regulation of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M008048200
P698PubMed publication ID11278380

P2093author name stringLi Z
Du X
Ruggeri ZM
Bodnar RJ
Englund GD
P2860cites workThe alpha and beta chains of human platelet glycoprotein Ib are both transmembrane proteins containing a leucine-rich amino acid sequenceQ24298201
Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factorQ24317407
Human platelet glycoprotein IX: an adhesive prototype of leucine-rich glycoproteins with flank-center-flank structuresQ24339565
Cloning of the alpha chain of human platelet glycoprotein Ib: a transmembrane protein with homology to leucine-rich alpha 2-glycoproteinQ24596653
Purification of botrocetin from Bothrops jararaca venom. Analysis of the botrocetin-mediated interaction between von Willebrand factor and the human platelet membrane glycoprotein Ib-IX complexQ28255295
Identification of a binding sequence for the 14-3-3 protein within the cytoplasmic domain of the adhesion receptor, platelet glycoprotein Ib alphaQ28278900
The cytoplasmic domain of the platelet glycoprotein Ibalpha is phosphorylated at serine 609.Q30811815
Decreased adhesion of giant (Bernard-Soulier) platelets to subendothelium. Further implications on the role of the von Willebrand factor in hemostasisQ33463842
Platelets have more than one binding site for von Willebrand factorQ33821754
Linkage of a membrane skeleton to integral membrane glycoproteins in human platelets. Identification of one of the glycoproteins as glycoprotein IbQ34562071
Functional domains on von Willebrand factor. Recognition of discrete tryptic fragments by monoclonal antibodies that inhibit interaction of von Willebrand factor with platelets and with collagenQ34613209
Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregationQ34624945
Plasma Aggregating Factor (Bovine) for Human Platelets: A Marker for Study of Antihemophilic and von Willebrand FactorsQ34737319
Venom coagglutinin: an activator of platelet aggregation dependent on von Willebrand factorQ35991709
Identification of a membrane skeleton in plateletsQ36218510
Analysis of the roles of 14-3-3 in the platelet glycoprotein Ib-IX-mediated activation of integrin alpha(IIb)beta(3) using a reconstituted mammalian cell expression modelQ36316299
The cytoplasmic domain of glycoprotein (GP) Ibalpha constrains the lateral diffusion of the GP Ib-IX complex and modulates von Willebrand factor bindingQ36892126
The cytoplasmic domain of the alpha-subunit of glycoprotein (GP) Ib mediates attachment of the entire GP Ib-IX complex to the cytoskeleton and regulates von Willebrand factor-induced changes in cell morphologyQ38357855
Human blood platelet adhesion to artery subendothelium is mediated by factor VIII-Von Willebrand factor bound to the subendotheliumQ40713235
Distinct structural attributes regulating von Willebrand factor A1 domain interaction with platelet glycoprotein Ibalpha under flowQ41609653
The role of platelet membrane glycoproteins Ib and IIb-IIIa in platelet adherence to human artery subendotheliumQ44359079
Crystal Structure of NMC-4 Fab anti-von Willebrand Factor A1 DomainQ44600729
Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).Q44645544
Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow.Q45967882
A novel ligand-binding site in the zeta-form 14-3-3 protein recognizing the platelet glycoprotein Ibalpha and distinct from the c-Raf-binding site.Q52532830
Ristocetin-dependent reconstitution of binding of von Willebrand factor to purified human platelet membrane glycoprotein Ib-IX complexQ69021307
Factor VIII/von Willebrand factor has potent lectin activityQ70469644
Design and construction of a linear shear stress flow chamberQ70564668
Signaling across the platelet adhesion receptor glycoprotein Ib-IX induces alpha IIbbeta 3 activation both in platelets and a transfected Chinese hamster ovary cell systemQ73827470
Glycoprotein (GP) Ib-IX-transfected cells roll on a von Willebrand factor matrix under flow. Importance of the GPib/actin-binding protein (ABP-280) interaction in maintaining adhesion under high shearQ74485103
P433issue20
P407language of work or nameEnglishQ1860
P1104number of pages8
P304page(s)16952-16959
P577publication date2001-02-26
P1433published inJournal of Biological ChemistryQ867727
P1476titleRegulation of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal
P478volume276

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cites work (P2860)
Q5233062214-3-3 proteins in platelet biology and glycoprotein Ib-IX signaling.
Q42092628A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications
Q28115628A novel interaction between FlnA and Syk regulates platelet ITAM-mediated receptor signaling and function
Q44693035A palmitylated peptide derived from the glycoprotein Ib beta cytoplasmic tail inhibits platelet activation
Q24603193Actin dynamics in platelets
Q36323239Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling
Q34529610Functional property of von Willebrand factor under flowing blood
Q28216564Genetic abnormalities of Bernard-Soulier syndrome
Q28344289Glycoprotein IIb-IIIa-dependent aggregation by glycoprotein Ibalpha is reinforced by a Src family kinase inhibitor (PP1)-sensitive signalling pathway
Q28193834Glycoprotein Ib cross-linking/ligation on echicetin-coated surfaces or echicetin-IgMkappa in stirred suspension activates platelets by cytoskeleton modulated calcium release
Q24681433Glycoprotein Ibalpha forms disulfide bonds with 2 glycoprotein Ibbeta subunits in the resting platelet
Q33395341Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex
Q30512462High shear-dependent loss of membrane integrity and defective platelet adhesion following disruption of the GPIbα-filamin interaction
Q42816498Identification of a unique filamin A binding region within the cytoplasmic domain of glycoprotein Ibalpha.
Q39596996Improved platelet survival after cold storage by prevention of glycoprotein Ibα clustering in lipid rafts.
Q52570780Insights into abnormal hemostasis in the Quebec platelet disorder from analyses of clot lysis.
Q38294908Interaction between platelet glycoprotein Ibalpha and filamin-1 is essential for glycoprotein Ib/IX receptor anchorage at high shear
Q28216733Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3
Q41916499Mechanism of platelet adhesion to von Willebrand factor and microparticle formation under high shear stress
Q37461882Membrane skeleton orchestrates the platelet glycoprotein (GP) Ib-IX complex clustering and signaling
Q33372673Molecular genetic analysis of a variant Bernard-Soulier syndrome due to compound heterozygosity for two novel glycoprotein Ibbeta mutations
Q42927395Platelet apoptosis by cold‐induced glycoprotein Ibα clustering
Q28586998Platelet biogenesis and functions require correct protein O-glycosylation
Q89879223RNA Sequencing (RNA-Seq) Based Transcriptome Analysis in Immune Response of Holstein Cattle to Killed Vaccine against Bovine Viral Diarrhea Virus Type I
Q28206117Redistribution of glycoprotein Ib within platelets in response to protease-activated receptors 1 and 4: roles of cytoskeleton and calcium
Q34152904Regulation of glycoprotein Ib-IX-von Willebrand factor interaction by cAMP-dependent protein kinase-mediated phosphorylation at Ser 166 of glycoprotein Ib(beta).
Q36057274Role of 14-3-3ζ in platelet glycoprotein Ibα-von Willebrand factor interaction-induced signaling
Q36266049Targeting shear stress-induced platelet activation: is lesion-specific antiplatelet therapy a realistic clinical goal?
Q34323610The organizing principle of the platelet glycoprotein Ib-IX-V complex.
Q36384795The role of Akt in the signaling pathway of the glycoprotein Ib-IX induced platelet activation
Q51807050The transmembrane domain of glycoprotein Ibbeta is critical to efficient expression of glycoprotein Ib-IX complex in the plasma membrane.
Q47861398Von Willebrand factor protects against acute CCl4-induced hepatotoxicity through phospho-p38 MAPK signaling pathway inhibition

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