Signaling across the platelet adhesion receptor glycoprotein Ib-IX induces alpha IIbbeta 3 activation both in platelets and a transfected Chinese hamster ovary cell system

scientific article published on 01 June 2000

Signaling across the platelet adhesion receptor glycoprotein Ib-IX induces alpha IIbbeta 3 activation both in platelets and a transfected Chinese hamster ovary cell system is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.275.22.16779
P698PubMed publication ID10828063

P2093author name stringY Zaffran
J E Fox
K B Reddy
E Negrescu
S C Meyer
P2860cites workInitiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factorQ24317407
Integrins: versatility, modulation, and signaling in cell adhesionQ27860844
Binding of purified 14-3-3 zeta signaling protein to discrete amino acid sequences within the cytoplasmic domain of the platelet membrane glycoprotein Ib-IX-V complexQ28258514
Identification of a binding sequence for the 14-3-3 protein within the cytoplasmic domain of the adhesion receptor, platelet glycoprotein Ib alphaQ28278900
Integrins: emerging paradigms of signal transductionQ28283614
Human platelet glycoprotein V: a surface leucine-rich glycoprotein related to adhesionQ28291698
Purification and preliminary characterization of the glycoprotein Ib complex in the human platelet membraneQ28291722
Interaction of platelet glycoprotein V with glycoprotein Ib-IX regulates expression of the glycoproteins and binding of von Willebrand factor to glycoprotein Ib-IX in transfected cellsQ28303342
Exposure of platelet fibrinogen receptors by ADP and epinephrineQ33473239
Molecular defects in interactions of platelets with the vessel wallQ33477754
von Willebrand factor binding to platelet GpIb initiates signals for platelet activationQ34208569
Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregationQ34549309
Linkage of a membrane skeleton to integral membrane glycoproteins in human platelets. Identification of one of the glycoproteins as glycoprotein IbQ34562071
Interaction of asialo von Willebrand factor with glycoprotein Ib induces fibrinogen binding to the glycoprotein IIb/IIIa complex and mediates platelet aggregationQ34624945
Identification of membrane proteins mediating the interaction of human plateletsQ36201513
Identification of a membrane skeleton in plateletsQ36218510
Integrin cytoplasmic domains mediate inside-out signal transductionQ36233869
Glanzmann thrombasthenia: deficient binding of von Willebrand factor to thrombin-stimulated plateletsQ36314768
Adhesive properties of the beta 3 integrins: comparison of GP IIb-IIIa and the vitronectin receptor individually expressed in human melanoma cellsQ36529569
GPIIb-IIIa: the responsive integrinQ37699902
The cytoplasmic domain of the alpha-subunit of glycoprotein (GP) Ib mediates attachment of the entire GP Ib-IX complex to the cytoskeleton and regulates von Willebrand factor-induced changes in cell morphologyQ38357855
Beta 1 integrin-mediated collagen gel contraction is stimulated by PDGF.Q41745333
Characterization of the unique mechanism mediating the shear-dependent binding of soluble von Willebrand factor to plateletsQ44139530
Specific synergy of multiple substrate-receptor interactions in platelet thrombus formation under flow.Q45967882
Regulation of alphaIIb beta3 function in human B lymphocytesQ48010217
Stimulation of P-selectin glycoprotein ligand-1 on mouse neutrophils activates β2 -integrin mediated cell attachment to ICAM-1Q58808003
Agonist-stimulated ligand binding by the platelet integrin alpha IIb beta 3 in a lymphocyte expression systemQ71703957
Glycoprotein (GP) Ib-IX-transfected cells roll on a von Willebrand factor matrix under flow. Importance of the GPib/actin-binding protein (ABP-280) interaction in maintaining adhesion under high shearQ74485103
Integrin affinity modulationQ77203120
P433issue22
P407language of work or nameEnglishQ1860
P304page(s)16779-16787
P577publication date2000-06-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleSignaling across the platelet adhesion receptor glycoprotein Ib-IX induces alpha IIbbeta 3 activation both in platelets and a transfected Chinese hamster ovary cell system
P478volume275

Reverse relations

cites work (P2860)
Q4448081614-3-3 zeta mediates integrin-induced activation of Cdc42 and Rac. Platelet glycoprotein Ib-IX regulates integrin-induced signaling by sequestering 14-3-3 zeta
Q3731497614-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function
Q42092628A critical role for 14-3-3zeta protein in regulating the VWF binding function of platelet glycoprotein Ib-IX and its therapeutic implications
Q34106615A thrombin receptor function for platelet glycoprotein Ib-IX unmasked by cleavage of glycoprotein V.
Q24603193Actin dynamics in platelets
Q40600278Activation of integrin alpha IIb beta 3 in the glycoprotein Ib-high population of a megakaryocytic cell line, CMK, by inside-out signaling
Q36323239Critical roles for the COOH-terminal NITY and RGT sequences of the integrin beta3 cytoplasmic domain in inside-out and outside-in signaling
Q37215693Endothelium-platelet interactions in inflammatory lung disease
Q28196450Helicobacter pylori binds von Willebrand factor and interacts with GPIb to induce platelet aggregation
Q58481471Integrin αIIbβ3 and shear-dependent action of glycoprotein ibα stimulate platelet-dependent thrombin formation in stirred plasma
Q28216733Lateral clustering of platelet GP Ib-IX complexes leads to up-regulation of the adhesive function of integrin alpha IIbbeta 3
Q28629042Localization of the adhesion receptor glycoprotein Ib-IX-V complex to lipid rafts is required for platelet adhesion and activation
Q41912198Membrane type-1 matrix metalloproteinase stimulates tumour cell-induced platelet aggregation: role of receptor glycoproteins
Q36324236Plasminogen activator inhibitor-1 detaches cells from extracellular matrices by inactivating integrins
Q40850991Platelets as an indicator of vascular repair in elderly Japanese men
Q50323663Possible mechanism underlying the association between height and vascular remodeling in elderly Japanese men.
Q28206117Redistribution of glycoprotein Ib within platelets in response to protease-activated receptors 1 and 4: roles of cytoskeleton and calcium
Q43559368Regulation of von Willebrand factor binding to the platelet glycoprotein Ib-IX by a membrane skeleton-dependent inside-out signal
Q36057274Role of 14-3-3ζ in platelet glycoprotein Ibα-von Willebrand factor interaction-induced signaling
Q43754584Specific inhibiting characteristics of tetramethylpyrazine, one of the active ingredients of the Chinese herbal medicine 'Chuanxiong,' on platelet thrombus formation under high shear rates
Q74248188Synergistic adhesive interactions and signaling mechanisms operating between platelet glycoprotein Ib/IX and integrin alpha IIbbeta 3. Studies in human platelets ans transfected Chinese hamster ovary cells
Q30437474The role of platelets in acute lung injury (ALI)
Q38069013Tissue-specific neutrophil recruitment into the lung, liver, and kidney.
Q73690479Tweezing apart von Willebrand factor-glycoprotein Ib-IX adhesive signaling
Q73690873von Willebrand factor stimulates thrombin-induced exposure of procoagulant phospholipids on the surface of fibrin-adherent platelets

Search more.