C-kit gene abnormalities in gastrointestinal stromal tumors (tumors of interstitial cells of Cajal

scientific article published in December 1999

C-kit gene abnormalities in gastrointestinal stromal tumors (tumors of interstitial cells of Cajal is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/J.1349-7006.1999.TB00715.X
P932PMC publication ID5926026
P698PubMed publication ID10665649
P5875ResearchGate publication ID12648981

P2093author name stringS Sakurai
T Fukasawa
A Tanaka
M Fukayama
J M Chong
P2860cites workGain-of-function mutations of c-kit in human gastrointestinal stromal tumorsQ28118852
Mutations of c-kit JM domain are found in a minority of human gastrointestinal stromal tumorsQ30303666
Muscle differentiation and clinicopathologic features of gastrointestinal stromal tumorsQ30311523
Disturbed intestinal movement, bile reflux to the stomach, and deficiency of c-kit-expressing cells in Ws/Ws mutant ratsQ32872145
W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activityQ34719633
Gastrointestinal pacemaker cell tumor (GIPACT): gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of CajalQ34747216
Embryonic form of smooth muscle myosin heavy chain (SMemb/MHC-B) in gastrointestinal stromal tumor and interstitial cells of CajalQ35754561
Mutations in exon 11 of c-Kit occur preferentially in malignant versus benign gastrointestinal stromal tumors and do not occur in leiomyomas or leiomyosarcomasQ35754637
A novel gain-of-function mutation of c-kit gene in gastrointestinal stromal tumorsQ40997984
Pacemaker cells in the gastrointestinal tract: interstitial cells of CajalQ41049564
Familial gastrointestinal stromal tumours with germline mutation of the KIT geneQ47714133
A clinicopathologic and immunohistochemical study of gastrointestinal stromal tumorsQ67741920
Gastrointestinal autonomic nerve tumors. A clinicopathological, immunohistochemical, and ultrastructural study of 12 casesQ70470140
Immunohistologic characterization of gastrointestinal stromal tumors: a study of 82 cases compared with 11 cases of leiomyomasQ70684982
Gastric adenoma ? carcinoma sequence with special reference to p53 and Ki-ras gene alterationsQ71796173
Immunohistochemical phenotyping and PCNA detection in gastrointestinal stromal tumorsQ71986134
Different patterns of DNA copy number changes in gastrointestinal stromal tumors, leiomyomas, and schwannomasQ74576133
Telomerase activity in gastrointestinal stromal tumorsQ77596968
KIT mutation portends poor prognosis in gastrointestinal stromal/smooth muscle tumorsQ77769095
P433issue12
P1104number of pages8
P304page(s)1321-1328
P577publication date1999-12-01
P1433published inJapanese Journal of Cancer ResearchQ26842384
P1476titleC-kit gene abnormalities in gastrointestinal stromal tumors (tumors of interstitial cells of Cajal
P478volume90

Reverse relations

cites work (P2860)
Q42108961A conserved quadruplex motif located in a transcription activation site of the human c-kit oncogene
Q27824814A great majority of GISTs with PDGFRA mutations represent gastric tumors of low or no malignant potential
Q39650027A meta-analysis of prognostic value of KIT mutation status in gastrointestinal stromal tumors
Q53674961A rare case of huge gastrointestinal stromal tumor (GIST) of the stomach extending into the posterior mediastinum.
Q40751543Abnormality of c-kit oncoprotein in certain patients with chronic myelogenous leukemia--potential clinical significance
Q34512501Allelic loss of 14q and 22q, NF2 mutation, and genetic instability occur independently of c-kit mutation in gastrointestinal stromal tumor
Q44490297Alterations of the c-kit gene in testicular germ cell tumors
Q64007381Carbazole Derivatives' Binding to c-KIT G-Quadruplex DNA
Q37099095Clinical significance of oncogenic KIT and PDGFRA mutations in gastrointestinal stromal tumours
Q47271715Clinicopathologic, phenotypic, and genotypic characteristics of gastrointestinal mesenchymal tumors
Q39070576Combined KIT and CTLA-4 Blockade in Patients with Refractory GIST and Other Advanced Sarcomas: A Phase Ib Study of Dasatinib plus Ipilimumab
Q44549290Deletion of Trp-557 and Lys-558 in the juxtamembrane domain of the c-kit protooncogene is associated with metastatic behavior of gastrointestinal stromal tumors
Q52023294Differentially expressed genes in gastric tumors identified by cDNA array.
Q44618426Endoscopic ultrasonography-guided fine needle aspiration biopsy in follow-up patients with gastrointestinal stromal tumours
Q44413967Frequent overexpression of the c-kit protein in large cell neuroendocrine carcinoma of the lung
Q42785249G-quadruplex-binding benzo[a]phenoxazines down-regulate c-KIT expression in human gastric carcinoma cells
Q41852979Gain-of-Function Mutations of Receptor Tyrosine Kinases in Gastrointestinal Stromal Tumors
Q38703103Gastrointestinal (GI) leiomyosarcoma (LMS) case series and review on diagnosis, management, and prognosis.
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Q37874125Gastrointestinal stromal tumors: molecular mechanisms and targeted therapies
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Q44075449KIT 1530ins6 mutation defines a subset of predominantly malignant gastrointestinal stromal tumors of intestinal origin
Q37451719Kinase inhibitors in cancer therapy
Q36856506Large gastrointestinal stromal tumor size does not imply early recurrence
Q33629772Malignant gastrointestinal stromal tumor of the gallbladder
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Q55246254Mutations in c-kit gene exons 9 and 13 in gastrointestinal stromal tumors among Japanese.
Q35745870Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases
Q73287799Mutations of c‐kit at exons 17/13 are rare but clinically relevant in human subjects
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Q44287763c-kit gene mutation at exon 17 or 13 is very rare in sporadic gastrointestinal stromal tumors
Q45095957c-kit gene mutations in intracranial germinomas
Q77648970c-kit mutations in gastrointestinal stromal tumors occur preferentially in the spindle rather than in the epithelioid cell variant