| scholarly article | Q13442814 |
| P356 | DOI | 10.1161/01.RES.0000020401.61826.EA |
| P698 | PubMed publication ID | 12065318 |
| P50 | author | Zoltan Ungvari | Q60324829 |
| P2093 | author name string | Gabor Kaley | |
| Akos Koller | |||
| Michael S Wolin | |||
| Anna Csiszar | |||
| John G Edwards | |||
| Pawel Kaminski | |||
| P433 | issue | 11 | |
| P921 | main subject | phenotypic change | Q113460568 |
| P304 | page(s) | 1159-1166 | |
| P577 | publication date | 2002-06-01 | |
| P1433 | published in | Circulation Research | Q2599020 |
| P1476 | title | Aging-induced phenotypic changes and oxidative stress impair coronary arteriolar function | |
| P478 | volume | 90 |
| Q39379525 | A facile synthesis of PLGA encapsulated cerium oxide nanoparticles: release kinetics and biological activity |
| Q36857395 | A new, potent poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging |
| Q48176579 | ACE2-EPC-EXs protect ageing ECs against hypoxia/reoxygenation-induced injury through the miR-18a/Nox2/ROS pathway |
| Q37474821 | Abnormal nitric oxide production in aged rat mesenteric arteries is mediated by NAD(P)H oxidase-derived peroxide. |
| Q48335448 | Activation of α1A -adrenoceptors desensitizes the rat aorta response to phenylephrine through a neuronal NOS pathway, a mechanism lost with ageing. |
| Q38667709 | Adaptation of the Coronary Microcirculation in Aging |
| Q34784446 | Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia |
| Q43069827 | Adult rats are more sensitive to the vascular effects induced by hyperhomocysteinemia than young rats |
| Q36902585 | Advanced age decreases local calcium signaling in endothelium of mouse mesenteric arteries in vivo |
| Q36986547 | Age Impaired endothelium-dependent vasodilation is improved by resveratrol in rat mesenteric arteries |
| Q37038750 | Age impairs Flk-1 signaling and NO-mediated vasodilation in coronary arterioles |
| Q38015080 | Age related cardiovascular dysfunction and effects of physical activity |
| Q47333148 | Age, weight and decompression sickness in rats. |
| Q91987858 | Age- and sex-dependent alteration of functions and epigenetic modifications of vessel and endothelium related biomarkers |
| Q36507295 | Age-associated proinflammatory secretory phenotype in vascular smooth muscle cells from the non-human primate Macaca mulatta: reversal by resveratrol treatment. |
| Q35142935 | Age-associated vascular oxidative stress, Nrf2 dysfunction, and NF-{kappa}B activation in the nonhuman primate Macaca mulatta. |
| Q37687931 | Age-related alterations in endothelial function of femoral artery in young SHR and WKY rats. |
| Q42914828 | Age-related changes in the contractile and passive arterial properties of murine mesenteric small arteries are altered by caveolin-1 knockout. |
| Q35661804 | Age-related decline of autocrine pituitary adenylate cyclase-activating polypeptide impairs angiogenic capacity of rat cerebromicrovascular endothelial cells. |
| Q35128658 | Age-related endothelial dysfunction : potential implications for pharmacotherapy |
| Q33764615 | Age-related impairment of conducted dilation in human coronary arterioles |
| Q46973591 | Age-related increase in xanthine oxidase activity in human plasma and rat tissues |
| Q36720761 | Aged lymphatic contractility: recent answers and new questions |
| Q46714717 | Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries |
| Q38253051 | Ageing and microvasculature |
| Q83333050 | Ageing reduces the compensatory vasodilatation during hypoxic exercise: the role of nitric oxide |
| Q35056988 | Aging and estrogen alter endothelial reactivity to reactive oxygen species in coronary arterioles |
| Q28390251 | Aging and vascular endothelial function in humans |
| Q30494862 | Aging blunts the dynamics of vasodilation in isolated skeletal muscle resistance vessels |
| Q35954921 | Aging enhances pressure-induced arterial superoxide formation |
| Q36863020 | Aging exacerbates microvascular endothelial damage induced by circulating factors present in the serum of septic patients. |
| Q34378137 | Aging exacerbates obesity-induced cerebromicrovascular rarefaction, neurovascular uncoupling, and cognitive decline in mice |
| Q36907952 | Aging exacerbates obesity-induced oxidative stress and inflammation in perivascular adipose tissue in mice: a paracrine mechanism contributing to vascular redox dysregulation and inflammation |
| Q45368955 | Aging impairs PI3K/Akt signaling and NO-mediated dilation in soleus muscle feed arteries |
| Q37372348 | Aging impairs flow-induced dilation in coronary arterioles: role of NO and H(2)O(2). |
| Q45299667 | Aging influences multiple incidices of oxidative stress in the aortic media of the Fischer 344/NNiaxBrown Norway/BiNia rat. |
| Q34545820 | Aging is associated with greater nuclear NF kappa B, reduced I kappa B alpha, and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans |
| Q28387247 | Aging, estrogen loss and epoxyeicosatrienoic acids (EETs) |
| Q33888187 | Aging-induced collateral dysfunction: impaired responsiveness of collaterals and susceptibility to apoptosis via dysfunctional eNOS signaling |
| Q37015907 | Aging-induced dysregulation of dicer1-dependent microRNA expression impairs angiogenic capacity of rat cerebromicrovascular endothelial cells |
| Q73304618 | Aging‐induced proinflammatory shift in cytokine expression profile in rat coronary arteries |
| Q35090344 | Aldose reductase and AGE-RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats. |
| Q36777049 | Aldose reductase, oxidative stress and diabetic cardiovascular complications |
| Q35906477 | Altered coronary vascular control during cold stress in healthy older adults |
| Q46405976 | Alternative Splicing of NOX4 in the Failing Human Heart. |
| Q35085406 | Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats |
| Q37831940 | Anti-inflammatory effects of resveratrol: possible role in prevention of age-related cardiovascular disease |
| Q37373849 | Anti-oxidative and anti-inflammatory vasoprotective effects of caloric restriction in aging: role of circulating factors and SIRT1. |
| Q28541815 | Anti-peroxynitrite treatment ameliorated vasorelaxation of resistance arteries in aging rats: involvement with NO-sGC-cGKs pathway |
| Q35373624 | Anti-platelet therapy: cyclo-oxygenase inhibition and the use of aspirin with particular regard to dual anti-platelet therapy |
| Q36977086 | Arginase and vascular aging |
| Q37391969 | Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. |
| Q37981952 | Atherosclerosis, vascular aging and therapeutic strategies. |
| Q40448492 | Attenuation of the physiological response to infection on adults over 65 years old admitted to the emergency room (ER). |
| Q37214322 | B6D2F1 Mice are a suitable model of oxidative stress-mediated impaired endothelium-dependent dilation with aging |
| Q34981422 | Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration |
| Q43106793 | Blunting of rapid onset vasodilatation and blood flow restriction in arterioles of exercising skeletal muscle with ageing in male mice |
| Q35087897 | Bone morphogenetic protein-2 induces proinflammatory endothelial phenotype |
| Q36399564 | COX isoforms in the cardiovascular system: understanding the activities of non-steroidal anti-inflammatory drugs |
| Q37728037 | Caloric restriction and heart function: is there a sensible link? |
| Q34001695 | Caloric restriction confers persistent anti-oxidative, pro-angiogenic, and anti-inflammatory effects and promotes anti-aging miRNA expression profile in cerebromicrovascular endothelial cells of aged rats |
| Q34207941 | Caloric restriction: powerful protection for the aging heart and vasculature. |
| Q36965956 | Can anti-inflammatory medications improve symptoms and reduce mortality in schizophrenia? |
| Q37598024 | Cardiovascular determinants of life span. |
| Q37825595 | Cardiovascular protection afforded by caloric restriction: essential role of nitric oxide synthase |
| Q91547414 | Cellular cross-talks in the diseased and aging heart |
| Q30235220 | Cerebral microhemorrhages: mechanisms, consequences, and prevention |
| Q35954840 | Chronic high blood flow potentiates shear stress-induced release of NO in arteries of aged rats |
| Q35102845 | Chronic high pressure-induced arterial oxidative stress: involvement of protein kinase C-dependent NAD(P)H oxidase and local renin-angiotensin system |
| Q36982850 | Chronic treatment with N-acetyl-cystein delays cellular senescence in endothelial cells isolated from a subgroup of atherosclerotic patients |
| Q90331275 | Circulating anti-geronic factors from heterochonic parabionts promote vascular rejuvenation in aged mice: transcriptional footprint of mitochondrial protection, attenuation of oxidative stress, and rescue of endothelial function by young blood |
| Q36709361 | Circulating factors induced by caloric restriction in the nonhuman primate Macaca mulatta activate angiogenic processes in endothelial cells. |
| Q37372863 | Coenzyme Q10 prevents accelerated cardiac aging in a rat model of poor maternal nutrition and accelerated postnatal growth |
| Q34986832 | Coronary circulation in hypertension and aging: an experimental study. |
| Q36956466 | Cytochrome P-450 2C9 signaling does not contribute to age-associated vascular endothelial dysfunction in humans |
| Q42466993 | Cytosolic NADPH may regulate differences in basal Nox oxidase-derived superoxide generation in bovine coronary and pulmonary arteries |
| Q36426806 | Decreased age-related cardiac dysfunction, myocardial nitrative stress, inflammatory gene expression, and apoptosis in mice lacking fatty acid amide hydrolase |
| Q46127624 | Determination of reactive oxygen and nitrogen species in rat aorta using the dichlorofluorescein assay |
| Q28583371 | Development of progressive aortic vasculopathy in a rat model of aging |
| Q44213320 | Different roles of PKC and MAP kinases in arteriolar constrictions to pressure and agonists |
| Q36056243 | Differential modulation of nitric oxide synthases in aging: therapeutic opportunities. |
| Q37730342 | Disease drivers of aging |
| Q36927443 | Distribution of the activity of the angiotensin-converting enzyme in the rat aorta and changes in the activity with aging and by the action of L-NAME. |
| Q53536668 | Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence. |
| Q44750431 | Effect of acute and chronic ascorbic acid on flow-mediated dilatation with sedentary and physically active human ageing |
| Q47230975 | Effects of Apelin on Cardiovascular Aging |
| Q35178856 | Effects of age and sex on cerebrovascular function in the rat middle cerebral artery |
| Q34753737 | Effects of aging and exercise training on spinotrapezius muscle microvascular PO2 dynamics and vasomotor control. |
| Q33914406 | Effects of aging on angiogenesis |
| Q33736693 | Elevated Circulating Trimethylamine N-Oxide Levels Contribute to Endothelial Dysfunction in Aged Rats through Vascular Inflammation and Oxidative Stress |
| Q34132827 | Endogenous sulfur dioxide protects against isoproterenol-induced myocardial injury and increases myocardial antioxidant capacity in rats |
| Q42733136 | Endothelial Nrf2 activation: a new target for resveratrol? |
| Q90484553 | Endothelial Regenerative Capacity and Aging: Influence of Diet, Exercise and Obesity |
| Q62587143 | Endothelial dysfunction and angiogenesis impairment in the ageing vasculature |
| Q38680112 | Endothelial dysfunction and vascular disease - a 30th anniversary update |
| Q42406006 | Endothelial dysfunction and vascular inflammation in type 2 diabetes: interaction of AGE/RAGE and TNF-alpha signaling |
| Q99564899 | Endothelial dysfunction in small arteries and early signs of atherosclerosis in ApoE knockout rats |
| Q34256015 | Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal ligation and puncture |
| Q37038972 | Endothelial function and vascular oxidative stress in long-lived GH/IGF-deficient Ames dwarf mice |
| Q33936813 | Estrogen and oxidative stress: A novel mechanism that may increase the risk for cardiovascular disease in women |
| Q33579228 | Estrogen replacement restores flow-induced vasodilation in coronary arterioles of aged and ovariectomized rats |
| Q34398574 | Estrogen-induced contraction of coronary arteries is mediated by superoxide generated in vascular smooth muscle |
| Q36042219 | Evidence of increased oxidative stress in aged mesenteric lymphatic vessels |
| Q38906962 | Exercise training reverses age-induced diastolic dysfunction and restores coronary microvascular function |
| Q37217931 | Exercise training reverses age-related decrements in endothelium-dependent dilation in skeletal muscle feed arteries |
| Q37270908 | Exposure to high or low glucose levels accelerates the appearance of markers of endothelial cell senescence and induces dysregulation of nitric oxide synthase |
| Q28564249 | Expression levels of TRPC1 and TRPC6 ion channels are reciprocally altered in aging rat aorta: implications for age-related vasospastic disorders |
| Q35590906 | Fetal origin of vascular aging |
| Q38994143 | Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging |
| Q46916981 | Gene transfer of extracellular superoxide dismutase protects against vascular dysfunction with aging |
| Q96303481 | Glucocorticoid Signaling and the Aging Heart |
| Q34182189 | Grape-derived polyphenols improve aging-related endothelial dysfunction in rat mesenteric artery: role of oxidative stress and the angiotensin system |
| Q35947412 | Growth hormone and IGF-1 deficiency exacerbate high-fat diet-induced endothelial impairment in obese Lewis dwarf rats: implications for vascular aging |
| Q64376806 | Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling |
| Q26822806 | Human conditions of insulin-like growth factor-I (IGF-I) deficiency |
| Q54192569 | Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease. |
| Q36410004 | IGF-1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging |
| Q46358618 | Impaired activity of adherens junctions contributes to endothelial dilator dysfunction in ageing rat arteries |
| Q39009007 | Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline |
| Q34307113 | Improvement of aging-associated cardiovascular dysfunction by the orally administered copper(II)-aspirinate complex |
| Q39193273 | In Development-A New Paradigm for Understanding Vascular Disease |
| Q37356167 | Increased NO bioavailability in aging male rats by genistein and exercise training: using 4, 5-diaminofluorescein diacetate. |
| Q30843714 | Increased aortic calpain-1 activity mediates age-associated angiotensin II signaling of vascular smooth muscle cells |
| Q28390561 | Increased arginase II activity contributes to endothelial dysfunction through endothelial nitric oxide synthase uncoupling in aged mice |
| Q35111176 | Increased proinflammatory and oxidant gene expression in circulating mononuclear cells in older adults: amelioration by habitual exercise |
| Q34751597 | Increased protein nitration in mitochondrial diseases: evidence for vessel wall involvement. |
| Q36956379 | Inflammation and endothelial dysfunction during aging: role of NF-kappaB |
| Q60950135 | Inflammation-Accelerated Senescence and the Cardiovascular System: Mechanisms and Perspectives |
| Q33577603 | Inhibition of iNOS protects endothelial-dependent vasodilation in aged rats |
| Q39213770 | Intermittent parathyroid hormone administration attenuates endothelial dysfunction in old rats |
| Q54978553 | Juvenile Traumatic Brain Injury Results in Cognitive Deficits Associated with Impaired Endoplasmic Reticulum Stress and Early Tauopathy. |
| Q33819035 | Kaempferol modulates pro-inflammatory NF-kappaB activation by suppressing advanced glycation endproducts-induced NADPH oxidase |
| Q37714641 | Korean red ginseng water extract restores impaired endothelial function by inhibiting arginase activity in aged mice |
| Q37170519 | Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. |
| Q35845272 | Liver-specific knockdown of IGF-1 decreases vascular oxidative stress resistance by impairing the Nrf2-dependent antioxidant response: a novel model of vascular aging |
| Q40976363 | Local renin-angiotensin system mediates endothelial dilator dysfunction in aging arteries |
| Q33689156 | Long-term high-fat consumption leads to downregulation of Akt phosphorylation of eNOS at Ser1177 and upregulation of Sirtuin-1 expression in rat cavernous tissue |
| Q37162511 | Longevity is associated with increased vascular resistance to high glucose-induced oxidative stress and inflammatory gene expression in Peromyscus leucopus |
| Q46726230 | Loss of adaptation to oxidative stress as a mechanism for aortic damage in aging rats |
| Q35990597 | Mechanisms involved in the aging-induced vascular dysfunction |
| Q57822218 | Mechanisms of Vascular Aging |
| Q34179571 | Mechanisms of vascular aging: new perspectives. |
| Q36713728 | Mechanisms underlying caloric restriction and lifespan regulation: implications for vascular aging. |
| Q50996967 | Melatonin counteracts the loss of agonist-evoked contraction of aortic rings induced by incubation. |
| Q37485286 | Metallothionein Prevents Age-Associated Cardiomyopathy via Inhibiting NF-κB Pathway Activation and Associated Nitrative Damage to 2-OGD. |
| Q39169210 | Microvascular NADPH oxidase in health and disease. |
| Q37780470 | Mitochondria and aging in the vascular system. |
| Q35987094 | Modulation of Macrophage Polarization and HMGB1-TLR2/TLR4 Cascade Plays a Crucial Role for Cardiac Remodeling in Senescence-Accelerated Prone Mice. |
| Q38129354 | Molecular aspects of the cardioprotective effect of exercise in the elderly |
| Q34433600 | Myogenic tone and reactivity of cerebral arteries in type II diabetic BBZDR/Wor rat |
| Q34994570 | NAD(P)H oxidase-derived reactive oxygen species contribute to age-related impairments of endothelium-dependent dilation in rat soleus feed arteries |
| Q37694936 | NO-Synthase Activity in Patients with Coronary Heart Disease Associated with Hypertension of Different Age Groups |
| Q41768344 | Nanoceria exhibit redox state-dependent catalase mimetic activity |
| Q34733988 | Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species |
| Q38791329 | New and old mechanisms associated with hypertension in the elderly. |
| Q64061417 | Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice |
| Q34046440 | Nicotinamide mononucleotide supplementation reverses vascular dysfunction and oxidative stress with aging in mice. |
| Q24645400 | Nitric oxide and peroxynitrite in health and disease |
| Q36889247 | Nitric oxide and superoxide interactions in the kidney and their implication in the development of salt-sensitive hypertension |
| Q34981297 | Nitrite supplementation reverses vascular endothelial dysfunction and large elastic artery stiffness with aging |
| Q28081466 | Noncoding RNA in age-related cardiovascular diseases |
| Q33281864 | Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain |
| Q33606974 | Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans |
| Q37373701 | Oxidative stress and accelerated vascular aging: implications for cigarette smoking |
| Q29347060 | Oxidative stress and endothelial dysfunction in pulmonary arteries of aged rats |
| Q90482481 | Oxidative stress-induced cellular senescence desensitizes cell growth and migration of vascular smooth muscle cells through down-regulation of platelet-derived growth factor receptor-beta |
| Q41810956 | Oxidative-nitrosative stress in a rabbit pup model of germinal matrix hemorrhage: role of NAD(P)H oxidase |
| Q38111280 | Peripheral circulation |
| Q35693660 | Perspectives of Targeting mTORC1-S6K1 in Cardiovascular Aging |
| Q36972415 | Pharmacological Strategies to Retard Cardiovascular Aging |
| Q50896297 | Physiological levels of thrombospondin-1 decrease NO-dependent vasodilation in coronary microvessels from aged rats. |
| Q46675845 | Poly(ADP-ribose)polymerase 1 inhibition protects against age-dependent endothelial dysfunction |
| Q30540978 | Postnatal exposure to voluntary exercise but not the antioxidant catechin protects the vasculature after a switch to an atherogenic environment in middle-age mice |
| Q37281306 | Predictors of Calf Arterial Compliance in Male Veterans With Psychiatric Diagnoses |
| Q90929432 | Prenatal hypoxia affected endothelium-dependent vasodilation in mesenteric arteries of aged offspring via increased oxidative stress |
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| Q34037245 | Pro-atherogenic shear rate patterns in the femoral artery of healthy older adults |
| Q44799815 | Proinflammatory phenotype of coronary arteries promotes endothelial apoptosis in aging |
| Q37276231 | Protective effect of extracellular superoxide dismutase on endothelial function during aging |
| Q43038442 | ROS-sensitive cytochrome P450 activity maintains endothelial dilatation in ageing but is transitory in dyslipidaemic mice. |
| Q43157291 | Reactive oxygen species and the control of vascular function |
| Q92106562 | Redox Regulation of the Microcirculation |
| Q37939948 | Redox balance in the aging microcirculation: new friends, new foes, and new clinical directions. |
| Q35954835 | Reduced release of nitric oxide to shear stress in mesenteric arteries of aged rats |
| Q50773985 | Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells: role of NF-kappaB inhibition. |
| Q33994850 | Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2. |
| Q34573984 | Resveratrol increases vascular oxidative stress resistance |
| Q37264427 | Resveratrol induces mitochondrial biogenesis in endothelial cells |
| Q34658269 | Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase. |
| Q35817892 | Right ventricular nitric oxide signaling in an ovine model of congenital heart disease: a preserved fetal phenotype |
| Q92221423 | Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment |
| Q30545747 | Role of caveolae in shear stress-mediated endothelium-dependent dilation in coronary arteries |
| Q33352994 | Role of inflammation in the pathogenesis of arterial stiffness |
| Q53850917 | Role of oxidative and nitrosative stress, longevity genes and poly(ADP-ribose) polymerase in cardiovascular dysfunction associated with aging. |
| Q37096869 | S-nitrosation of arginase 1 requires direct interaction with inducible nitric oxide synthase |
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| Q37198120 | Single dose treatment with PARP-inhibitor INO-1001 improves aging-associated cardiac and vascular dysfunction |
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