scholarly article | Q13442814 |
P50 | author | Jeffrey A Kern | Q63373813 |
P2093 | author name string | Jinbo Liu | |
P2860 | cites work | Thrombin regulates vascular smooth muscle cell growth and heat shock proteins via the JAK-STAT pathway | Q43559449 |
Neuregulin-1 and human epidermal growth factor receptors 2 and 3 play a role in human lung development in vitro. | Q52169558 | ||
Neuregulin-4: a novel growth factor that acts through the ErbB-4 receptor tyrosine kinase | Q22009917 | ||
Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4 | Q24336447 | ||
Identification of heregulin, a specific activator of p185erbB2 | Q24338146 | ||
Humanization of an anti-p185HER2 antibody for human cancer therapy | Q24561842 | ||
ErbB receptor-induced activation of stat transcription factors is mediated by Src tyrosine kinases | Q28198475 | ||
Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2 | Q28609160 | ||
Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and interleukin-6 | Q28637521 | ||
Stat3 as an oncogene | Q29614606 | ||
STATs in oncogenesis | Q29617571 | ||
Janus kinases and their role in growth and disease | Q33664276 | ||
Transcriptional regulation of the cyclin D1 promoter by STAT5: its involvement in cytokine-dependent growth of hematopoietic cells | Q33854194 | ||
Divergent roles of STAT1 and STAT5 in malignancy as revealed by gene disruptions in mice | Q33941361 | ||
C-erbB-2 expression and codon 12 K-ras mutations both predict shortened survival for patients with pulmonary adenocarcinomas. | Q34124421 | ||
HER2/neu: mechanisms of dimerization/oligomerization | Q34130541 | ||
Epidermal growth factor induces the tyrosine phosphorylation and nuclear translocation of Stat 5 in mouse liver | Q34312998 | ||
Spacing of palindromic half sites as a determinant of selective STAT (signal transducers and activators of transcription) DNA binding and transcriptional activity | Q34532143 | ||
The type 1 (EGFR-related) family of growth factor receptors and their ligands | Q35264192 | ||
Constitutive activation of Stat3 signaling abrogates apoptosis in squamous cell carcinogenesis in vivo | Q35676433 | ||
Insect cell-expressed p180erbB3 possesses an impaired tyrosine kinase activity | Q35684026 | ||
Constitutive activation of a slowly migrating isoform of Stat3 in mycosis fungoides: tyrphostin AG490 inhibits Stat3 activation and growth of mycosis fungoides tumor cell lines | Q36239779 | ||
Demonstration of an interferon gamma-dependent tumor surveillance system in immunocompetent mice | Q36497106 | ||
Transcriptionally active Stat1 is required for the antiproliferative effects of both interferon alpha and interferon gamma | Q37432208 | ||
An epidermal growth factor receptor/Jak2 tyrosine kinase domain chimera induces tyrosine phosphorylation of Stat5 and transduces a growth signal in hematopoietic cells | Q38354196 | ||
Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research | Q40445359 | ||
A neu acquaintance for erbB3 and erbB4: a role for receptor heterodimerization in growth signaling | Q40673334 | ||
How receptor tyrosine kinases activate Ras. | Q40778358 | ||
Epidermal growth factor (EGF) receptor kinase-independent signaling by EGF. | Q40816275 | ||
ErbB-2 kinase is required for constitutive stat 3 activation in malignant human lung epithelial cells | Q40925406 | ||
IL-3 dependent regulation of Bcl-xL gene expression by STAT5 in a bone marrow derived cell line | Q40937398 | ||
Regulation of heregulin beta1-induced differentiation in a human breast carcinoma cell line by the extracellular-regulated kinase (ERK) pathway | Q41013193 | ||
Growth effects of alpha-interferon but not of bombesin or angiotensin II are mediated by activation of STAT proteins | Q41029044 | ||
STAT activation by epidermal growth factor (EGF) and amphiregulin. Requirement for the EGF receptor kinase but not for tyrosine phosphorylation sites or JAK1. | Q41205161 | ||
Inhibition of human lung cancer cell line growth by an anti-p185HER2 antibody. | Q41524948 | ||
Mechanisms of p185HER2 expression in human non-small cell lung cancer cell lines | Q41633694 | ||
Specificity within the EGF family/ErbB receptor family signaling network | Q41721612 | ||
Pathogenic poxviruses reveal viral strategies to exploit the ErbB signaling network | Q42657008 | ||
Activation of Stat3 preassembled with platelet-derived growth factor beta receptors requires Src kinase activity | Q42801916 | ||
P433 | issue | 3 | |
P304 | page(s) | 306-313 | |
P577 | publication date | 2002-09-01 | |
P1433 | published in | American Journal of Respiratory Cell and Molecular Biology | Q4744268 |
P1476 | title | Neuregulin-1 activates the JAK-STAT pathway and regulates lung epithelial cell proliferation | |
P478 | volume | 27 |
Q30496278 | A sequence-based approach to identify reference genes for gene expression analysis |
Q38353138 | Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells |
Q35112995 | An association study of polymorphisms in JAK3 gene with lung cancer in the Korean population |
Q48455124 | Bleomycin-induced pulmonary fibrosis is attenuated by a monoclonal antibody targeting HER2. |
Q27853182 | Clinical Translation and Validation of a Predictive Biomarker for Patritumab, an Anti-human Epidermal Growth Factor Receptor 3 (HER3) Monoclonal Antibody, in Patients With Advanced Non-small Cell Lung Cancer |
Q35085222 | Constitutive activation of JAK3/STAT3 in colon carcinoma tumors and cell lines: inhibition of JAK3/STAT3 signaling induces apoptosis and cell cycle arrest of colon carcinoma cells |
Q36776754 | Cucurbitacin I inhibits Rac1 activation in breast cancer cells by a reactive oxygen species-mediated mechanism and independently of Janus tyrosine kinase 2 and P-Rex1. |
Q34412268 | DNA methylation profiles of airway epithelial cells and PBMCs from healthy, atopic and asthmatic children |
Q35135228 | Delineating the prime mover action of progesterone for endometrial receptivity in primates |
Q37032468 | Differential changes in Neuregulin-1 signaling in major brain regions in a lipopolysaccharide-induced neuroinflammation mouse model. |
Q64982800 | Doxycycline inhibits electric field-induced migration of non-small cell lung cancer (NSCLC) cells. |
Q49396162 | Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin |
Q38977527 | ERBB3 is required for metastasis formation of melanoma cells |
Q39570766 | Endogenous expression of Neuregulin-1 (Nrg1) as a potential modulator of prolactin (PRL) secretion in GH3 cells |
Q37675239 | HER2-Positive Metastatic Breast Cancer Patients Receiving Pertuzumab in a Community Oncology Practice Setting: Treatment Patterns and Outcomes |
Q37714469 | Heparan sulfate in lung morphogenesis: The elephant in the room |
Q35013546 | Host-Mycobacterium avium subsp. paratuberculosis interactome reveals a novel iron assimilation mechanism linked to nitric oxide stress during early infection |
Q27002075 | Human epidermal growth factor receptor signaling in acute lung injury |
Q40230876 | Inactivation of neuregulin-1 by nitration. |
Q44559500 | Inhibition of JAK3 induces apoptosis and decreases anaplastic lymphoma kinase activity in anaplastic large cell lymphoma |
Q47931199 | Inhibitory actions of the NRG-1/ErbB4 pathway in macrophages during tissue fibrosis in the heart, skin, and lung. |
Q89993110 | Interleukin-6 is required for Neuregulin-1 induced HER2 signaling in lung epithelium |
Q40075798 | JAK kinases promote invasiveness in VHL-mediated renal cell carcinoma by a suppressor of cytokine signaling-regulated, HIF-independent mechanism |
Q36178175 | JAK-STAT pathway in carcinogenesis: is it relevant to cholangiocarcinoma progression? |
Q35031161 | Janus kinase-3 dependent inflammatory responses in allergic asthma |
Q55364809 | Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells. |
Q35528090 | Neuregulin receptor ErbB4 functions as a transcriptional cofactor for the expression of surfactant protein B in the fetal lung |
Q48897438 | Neuregulin-1 (Nrg1) is mainly expressed in rat pituitary gonadotroph cells and possibly regulates prolactin (PRL) secretion in a juxtacrine manner |
Q37190917 | Neuregulin-1 (Nrg1) signaling has a preventive role and is altered in the frontal cortex under the pathological conditions of Alzheimer's disease |
Q34784406 | Neuregulin-1β regulation of embryonic endothelial progenitor cell survival |
Q64964110 | Neuregulin1 acts as a suppressor in human lung adenocarcinoma via AKT and ERK1/2 pathway. |
Q37982433 | Pertuzumab: in the first-line treatment of HER2-positive metastatic breast cancer |
Q39886940 | Population pharmacokinetic analysis of patritumab, a HER3 inhibitor, in subjects with advanced non-small cell lung cancer (NSCLC) or solid tumors |
Q37539350 | Protein Phosphatase-1 Regulates Expression of Neuregulin-1. |
Q90291834 | Quantification of EGFR family in canine mammary ductal carcinomas in situ: implications on the histological graduation |
Q36745834 | Resection of non-small cell lung cancers reverses tumor-induced gene expression changes in the peripheral immune system |
Q36086059 | Role of STAT3 in lung cancer |
Q36202795 | Roles for neuregulins in human cancer. |
Q37707158 | Signalling between microvascular endothelium and cardiomyocytes through neuregulin |
Q40336558 | Tanapoxvirus lacking the 15L gene inhibits melanoma cell growth in vitro by inducing interferon-λ1 release |
Q37135372 | The ERBB3 receptor in cancer and cancer gene therapy |
Q38352587 | The Potential of panHER Inhibition in Cancer |
Q28067559 | The genetic and epigenetic landscapes of the epithelium in asthma |
Q36704645 | The role of STATs in lung carcinogenesis: an emerging target for novel therapeutics |
Q37452234 | Transcription factor ETV1 is essential for rapid conduction in the heart |
Q38343679 | Transcriptional response of a common permissive cell type to infection by two diverse alphaherpesviruses |
Q40138970 | Treatment of human epidermal growth factor receptor 2-overexpressing breast cancer xenografts with multiagent HER-targeted therapy |
Q37124053 | WASF3 provides the conduit to facilitate invasion and metastasis in breast cancer cells through HER2/HER3 signaling |
Q34096085 | miR-21 promotes the differentiation of hair follicle-derived neural crest stem cells into Schwann cells |
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