Pharmacokinetics and pharmacodynamics of methadone enantiomers after coadministration with amprenavir in opioid-dependent subjects

scientific article published in September 2004

Pharmacokinetics and pharmacodynamics of methadone enantiomers after coadministration with amprenavir in opioid-dependent subjects is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1592/PHCO.24.13.1110.38091
P698PubMed publication ID15460171

P2093author name stringCraig W Hendrix
Mary Beth Wire
Yu Lou
George E Bigelow
Edward J Fuchs
Elizabeth Martinez
Jerry W Snidow
Jared Christopher
John Wakeford
P2860cites workMethadone N-demethylation in human liver microsomes: lack of stereoselectivity and involvement of CYP3A4Q24564971
Decreased methadone effect after ritonavir initiationQ28368991
Absence of opioid withdrawal symptoms in patients receiving methadone and the protease inhibitor lopinavir-ritonavirQ32067953
Pharmacokinetic Interaction between amprenavir and rifabutin or rifampin in healthy malesQ33981408
Stereoselective metabolism of methadone N-demethylation by cytochrome P4502B6 and 2C19.Q34543319
Weak Binding of VX-478 to Human Plasma Proteins and Implications for Anti-Human Immunodeficiency Virus TherapyQ38508315
Pharmacokinetic interaction between amprenavir and clarithromycin in healthy male volunteersQ39473480
The mu1, mu2, delta, kappa opioid receptor binding profiles of methadone stereoisomers and morphineQ44335550
High-dose methadone produces superior opioid blockade and comparable withdrawal suppression to lower doses in opioid-dependent humansQ44338361
Onset, magnitude and duration of opioid blockade produced by buprenorphine and naltrexone in humansQ44352672
Lack of methadone dose alterations or withdrawal symptoms during therapy with lopinavir/ritonavirQ44539534
The protease inhibitor lopinavir-ritonavir may produce opiate withdrawal in methadone-maintained patientsQ44540993
The effects of once-daily saquinavir/minidose ritonavir on the pharmacokinetics of methadoneQ44770188
Pharmacokinetic interaction between ketoconazole and amprenavir after single doses in healthy men.Q44866694
Metabolism of amprenavir in liver microsomes: role of CYP3A4 inhibition for drug interactionsQ47900779
Effects of buprenorphine and methadone in methadone-maintained subjects.Q54493915
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
opioidQ427523
enantiomerQ494483
pharmacodynamicsQ725307
P304page(s)1110-1121
P577publication date2004-09-01
P1433published inPharmacotherapyQ7180800
P1476titlePharmacokinetics and pharmacodynamics of methadone enantiomers after coadministration with amprenavir in opioid-dependent subjects
P478volume24

Reverse relations

cites work (P2860)
Q27692040A review of pharmacological interactions between HIV or hepatitis C virus medications and opioid agonist therapy: implications and management for clinical practice
Q37000733Drug interactions in the management of HIV infection: an update
Q36399718Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug
Q36641870Mechanism of ritonavir changes in methadone pharmacokinetics and pharmacodynamics: II. Ritonavir effects on CYP3A and P-glycoprotein activities
Q34633457Mechanisms of pharmacokinetic and pharmacodynamic drug interactions associated with ritonavir-enhanced tipranavir
Q91386089Methadone Metabolism and Drug-Drug Interactions: In Vitro and In Vivo Literature Review
Q37950478Methadone: a review of drug-drug and pathophysiological interactions
Q44346297Pharmacokinetic interactions between darunavir/ritonavir and opioid maintenance therapy using methadone or buprenorphine/naloxone
Q42660244Pharmacokinetics and pharmacodynamics of methadone enantiomers after coadministration with fosamprenavir-ritonavir in opioid-dependent subjects
Q34487284Pharmacokinetics of methadone

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