Kinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling

scientific article published on 22 September 2003

Kinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M308318200
P698PubMed publication ID14506231

P50authorSanford BernsteinQ42880156
Michael A. GeevesQ50688013
Miklos NyitraiQ87242985
P2093author name stringBecky M Miller
P2860cites workCrystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke stateQ27765344
The myosin power strokeQ28216645
Fluorescent coumarin-labeled nucleotides to measure ADP release from actomyosinQ28346188
Transient kinetic analysis of the 130-kDa myosin I (MYR-1 gene product) from rat liver. A myosin I designed for maintenance of tension?Q28369644
Functional domains of the Drosophila melanogaster muscle myosin heavy-chain gene are encoded by alternatively spliced exonsQ30450397
Myosin functional domains encoded by alternative exons are expressed in specific thoracic muscles of DrosophilaQ30451591
A flash photolysis fluorescence/light scattering apparatus for use with sub microgram quantities of muscle proteinsQ30660300
Kinetic differences at the single molecule level account for the functional diversity of rabbit cardiac myosin isoformsQ30756973
Kinetic differences in cardiac myosins with identical loop 1 sequencesQ31559470
Alternative exon-encoded regions of Drosophila myosin heavy chain modulate ATPase rates and actin sliding velocity.Q31778397
Spatially and temporally regulated expression of myosin heavy chain alternative exons during Drosophila embryogenesis.Q32079160
The converter domain modulates kinetic properties of Drosophila myosinQ33185427
Structural mechanism of muscle contraction.Q33953597
Determining structure/function relationships for sarcomeric myosin heavy chain by genetic and transgenic manipulation of DrosophilaQ34040305
ATPase activity of myosin correlated with speed of muscle shorteningQ36427606
ADP dissociation from actomyosin subfragment 1 is sufficiently slow to limit the unloaded shortening velocity in vertebrate muscleQ37676214
How molecular motors workQ40649507
An insert in the motor domain determines the functional properties of expressed smooth muscle myosin isoformsQ42062781
Differing ADP release rates from myosin heavy chain isoforms define the shortening velocity of skeletal muscle fibers.Q43759055
The myosin converter domain modulates muscle performanceQ43922164
Alternative myosin hinge regions are utilized in a tissue-specific fashion that correlates with muscle contraction speedQ45267700
A 32 degree tail swing in brush border myosin I on ADP release.Q46016894
A 35-A movement of smooth muscle myosin on ADP release.Q46023129
The effect of EDTA on spectral properties of ATP-, ADP-, and ITP-G-actinQ47955900
The ATPase kinetics of insect fibrillar flight muscle myosin subfragment-1.Q52456987
Fine tuning a molecular motor: the location of alternative domains in the Drosophila myosin head.Q52558743
Exchange between inorganic phosphate and adenosine 5'-triphosphate in the medium by actomyosin subfragment 1.Q52763844
Modulation of Actin Affinity and Actomyosin Adenosine Triphosphatase by Charge Changes in the Myosin Motor Domain†Q58491145
Check your equipmentQ58992292
P433issue50
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)50293-50300
P577publication date2003-09-22
P1433published inJournal of Biological ChemistryQ867727
P1476titleKinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling
P478volume278

Reverse relations

cites work (P2860)
Q36083020A variable domain near the ATP-binding site in Drosophila muscle myosin is part of the communication pathway between the nucleotide and actin-binding sites.
Q37265530Alternative S2 hinge regions of the myosin rod affect myofibrillar structure and myosin kinetics.
Q35059426Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head
Q35782911Alternative relay and converter domains tune native muscle myosin isoform function in Drosophila.
Q35768746An exceptionally fast actomyosin reaction powers insect flight muscle
Q86938290Ankyrin domain of myosin 16 influences motor function and decreases protein phosphatase catalytic activity
Q35749528Biomolecular motors: the F1-ATPase paradigm
Q36553476Conformational changes at the nucleotide site in the presence of bound ADP do not set the velocity of fast Drosophila myosins
Q41200755Drosophila UNC-45 prevents heat-induced aggregation of skeletal muscle myosin and facilitates refolding of citrate synthase.
Q35998580Expression of the inclusion body myopathy 3 mutation in Drosophila depresses myosin function and stability and recapitulates muscle inclusions and weakness
Q52655823Five Alternative Myosin Converter Domains Influence Muscle Power, Stretch Activation, and Kinetics.
Q36178999Invertebrate muscles: muscle specific genes and proteins
Q33987018Mutating the converter-relay interface of Drosophila myosin perturbs ATPase activity, actin motility, myofibril stability and flight ability
Q49651499Myosin storage myopathy mutations yield defective myosin filament assembly in vitro and disrupted myofibrillar structure and function in vivo
Q34829829Myosin subfragment 1 structures reveal a partially bound nucleotide and a complex salt bridge that helps couple nucleotide and actin binding
Q35945731Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency
Q27671822Processive Steps in the Reverse Direction Require Uncoupling of the Lead Head Lever Arm of Myosin VI
Q37946073Shaking the myosin family tree: biochemical kinetics defines four types of myosin motor
Q43219953Similarities and differences between frozen-hydrated, rigor acto-S1 complexes of insect flight and chicken skeletal muscles
Q30381592The Relay/Converter Interface Influences Hydrolysis of ATP by Skeletal Muscle Myosin II.
Q34099091The influence of myosin converter and relay domains on cross-bridge kinetics of Drosophila indirect flight muscle
Q42101523The regulation of myosin binding to actin filaments by Lethocerus troponin.
Q30352527The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms.
Q42093754Transgenic expression and purification of myosin isoforms using the Drosophila melanogaster indirect flight muscle system
Q35150221Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities

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