human | Q5 |
P8446 | Gateway to Research person ID | 101C0D19-FEE1-435A-8E3B-51CB5E1E7A61 |
P496 | ORCID iD | 0000-0002-9364-8898 |
P1153 | Scopus author ID | 7006458343 |
P69 | educated at | University of Bristol | Q459506 |
University of Birmingham | Q223429 | ||
P108 | employer | University of Kent | Q1516684 |
University of California | Q184478 | ||
Max Planck Institute for Molecular Genetics | Q1721667 | ||
P734 | family name | Geeves | Q27631735 |
Geeves | Q27631735 | ||
Geeves | Q27631735 | ||
P735 | given name | Michael | Q4927524 |
Michael | Q4927524 | ||
P106 | occupation | researcher | Q1650915 |
P21 | sex or gender | male | Q6581097 |
Q39283651 | 13 Cryoenzymology: The study of enzyme catalysis at subzero temperatures |
Q43001941 | A kinetic model of the co-operative binding of calcium and ADP to scallop (Argopecten irradians) heavy meromyosin |
Q92764676 | A micro-volume adaptation of a stopped-flow system; use with μg quantities of muscle proteins |
Q74229259 | A modulatory role for the troponin T tail domain in thin filament regulation |
Q58798735 | A novel live-cell imaging system reveals a reversible hydrostatic pressure impact on cell-cycle progression |
Q24534408 | A novel pressure-jump apparatus for the microvolume analysis of protein-ligand and protein-protein interactions: its application to nucleotide binding to skeletal-muscle and smooth-muscle myosin subfragment-1 |
Q71971068 | A novel stopped-flow method for measuring the affinity of actin for myosin head fragments using microgram quantities of protein |
Q35589202 | A systematic nomenclature for mammalian tropomyosin isoforms |
Q36083020 | A variable domain near the ATP-binding site in Drosophila muscle myosin is part of the communication pathway between the nucleotide and actin-binding sites. |
Q43574547 | ADP binding induces an asymmetry between the heads of unphosphorylated myosin. |
Q69780324 | ATP-induced dissociation of rabbit skeletal actomyosin subfragment 1. Characterization of an isomerization of the ternary acto-S1-ATP complex |
Q50687915 | Acetylation regulates tropomyosin function in the fission yeast Schizosaccharomyces pombe. |
Q121177104 | Acetylation stabilises calmodulin‐regulated calcium signalling |
Q52573197 | Actin residue glu(93) is identified as an amino acid affecting myosin binding. |
Q73838653 | Actin-tropomyosin activation of myosin subfragment 1 ATPase and thin filament cooperativity. The role of tropomyosin flexibility and end-to-end interactions |
Q34129446 | Actomyosin kinetics and in vitro motility of wild-type Drosophila actin and the effects of two mutations in the Act88F gene. |
Q42372196 | Actomyosin kinetics of pure fast and slow rat myosin isoforms studied by in vitro motility assay approach. |
Q36007515 | Adenosine diphosphate and strain sensitivity in myosin motors. |
Q121177154 | Alpha and beta myosin isoforms and human atrial and ventricular contraction |
Q98575250 | Alternative N-terminal regions of Drosophila myosin heavy chain II regulate communication of the purine binding loop with the essential light chain |
Q35059426 | Alternative exon 9-encoded relay domains affect more than one communication pathway in the Drosophila myosin head |
Q27674286 | An enzyme-trap approach allows isolation of intermediates in cobalamin biosynthesis |
Q42386692 | Analysis of biophysical and functional consequences of tropomyosin-fluorescent protein fusions. |
Q52306811 | Bisphosphorylation of cardiac troponin I modulates the Ca(2+)-dependent binding of myosin subfragment S1 to reconstituted thin filaments. |
Q30481688 | Calcium sensitivity of the cross-bridge cycle of Myo1c, the adaptation motor in the inner ear |
Q45173722 | Changes in Mg2+ ion concentration and heavy chain phosphorylation regulate the motor activity of a class I myosin |
Q44020719 | Changes in catalytic activity and association state of pyruvate carboxylase which are dependent on enzyme concentration. |
Q38326456 | Characterization of the cardiac holotroponin complex reconstituted from native cardiac troponin T and recombinant I and C. |
Q54014357 | Characterization of the equilibrium between blocked and closed states of muscle thin filaments. |
Q33484633 | Contractile activation and force generation in skinned rabbit muscle fibres: effects of hydrostatic pressure. |
Q42119619 | Contractility parameters of human β-cardiac myosin with the hypertrophic cardiomyopathy mutation R403Q show loss of motor function. |
Q33922832 | Cooperative [Ca²+]-dependent regulation of the rate of myosin binding to actin: solution data and the tropomyosin chain model. |
Q42267863 | Cooperative regulation of myosin-S1 binding to actin filaments by a continuous flexible Tm-Tn chain |
Q34181116 | Cooperative regulation of myosin-actin interactions by a continuous flexible chain I: actin-tropomyosin systems. |
Q34181121 | Cooperative regulation of myosin-actin interactions by a continuous flexible chain II: actin-tropomyosin-troponin and regulation by calcium. |
Q42690203 | Cooperativity and switching within the three-state model of muscle regulation. |
Q40126797 | Cooperativity between the two heads of rabbit skeletal muscle heavy meromyosin in binding to actin. |
Q34562133 | Cooperativity in the Ca2+ regulation of muscle contraction. |
Q42783964 | Cross-talk, cross-bridges, and calcium activation of cardiac contraction. |
Q98171250 | Cryo-EM and Molecular Docking Shows Myosin Loop 4 Contacts Actin and Tropomyosin on Thin Filaments |
Q41967903 | Cryptococcus neoformans senses CO2 through the carbonic anhydrase Can2 and the adenylyl cyclase Cac1 |
Q41192724 | Crystallization and preliminary X-ray crystallographic analysis of full-length yeast tropomyosin 2 from Saccharomyces cerevisiae. |
Q58491146 | Dictyostelium discoideumMyosin II: Characterization of Functional Myosin Motor Fragments† |
Q46917024 | Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis |
Q42690345 | Differential regulation of the actomyosin interaction by skeletal and cardiac troponin isoforms. |
Q58491140 | Differential scanning calorimetric study of the thermal unfolding of the motor domain fragments of Dictyostelium discoideum myosin II |
Q43759055 | Differing ADP release rates from myosin heavy chain isoforms define the shortening velocity of skeletal muscle fibers. |
Q73037295 | Diffusional barrier crossing in a two-state protein folding reaction |
Q52318721 | Dilated cardiomyopathy myosin mutants have reduced force-generating capacity. |
Q118055774 | Distinct effects of two hearing loss–associated mutations in the sarcomeric myosin MYH7b |
Q52576029 | Drosophila ACT88F indirect flight muscle-specific actin is not N-terminally acetylated: a mutation in N-terminal processing affects actin function. |
Q37371692 | Drug effect unveils inter-head cooperativity and strain-dependent ADP release in fast skeletal actomyosin |
Q93519366 | Dynamic interaction between actin and myosin subfragment 1 in the presence of ADP |
Q42606576 | Dynamics of the muscle thin filament regulatory switch: the size of the cooperative unit. |
Q33941983 | Dynamics of tropomyosin in muscle fibers as monitored by saturation transfer EPR of bi-functional probe. |
Q121177152 | Effect of Myosin Isoforms on Cardiac Muscle Twitch of Mice, Rats and Humans |
Q121177149 | Effects of Hydrostatic-Pressure on Muscle Contraction: A Look Back on Some Experimental Findings |
Q71971060 | Effects of hydrostatic pressure on fatiguing frog muscle fibres |
Q43005989 | Effects of pressure on equatorial x-ray fiber diffraction from skeletal muscle fibers. |
Q34188103 | Effects of two familial hypertrophic cardiomyopathy mutations in alpha-tropomyosin, Asp175Asn and Glu180Gly, on the thermal unfolding of actin-bound tropomyosin |
Q36937943 | Erratum to: Identification of functional differences between recombinant human α and β cardiac myosin motors. |
Q93190721 | Evidence of functional deficits at the single muscle fiber level in experimentally-induced renal insufficiency |
Q121177151 | Exploring the super-relaxed state of myosin in myofibrils from fast-twitch, slow-twitch, and cardiac muscle |
Q42722057 | FAD binding, cobinamide binding and active site communication in the corrin reductase (CobR) |
Q37126952 | Fast pressure jumps can perturb calcium and magnesium binding to troponin C F29W |
Q73165952 | Force generation upon hydrostatic pressure release in tetanized intact frog muscle fibres |
Q52568686 | Functional and biophysical analyses of the class XIV Toxoplasma gondii myosin D. |
Q36898618 | Functional homodimers and heterodimers of recombinant smooth muscle tropomyosin |
Q93112689 | High-speed imaging of glutamate release with genetically encoded sensors |
Q36032815 | Identification of functional differences between recombinant human α and β cardiac myosin motors |
Q32872095 | In vitro formation and characterization of the skeletal muscle α·β tropomyosin heterodimers |
Q74104012 | Inhibition of actin-myosin subfragment 1 ATPase activity by troponin I and IC: relationship to the thin filament states of muscle |
Q74252125 | Interaction of actin and ADP with the head domain of smooth muscle myosin: implications for strain-dependent ADP release in smooth muscle |
Q43002735 | Interactions of the two heads of scallop (Argopecten irradians) heavy meromyosin with actin: influence of calcium and nucleotides |
Q34182309 | Ionic interactions play a role in the regulatory mechanism of scallop heavy meromyosin. |
Q44761193 | Isolation and kinetic characterisation of myosin and myosin S1 from the Drosophila indirect flight muscles. |
Q24535798 | KIF1D is a fast non-processive kinesin that demonstrates novel K-loop-dependent mechanochemistry. |
Q58491137 | Kinetic Analysis ofDictyostelium discoideumMyosin Motor Domains with Glycine-to-Alanine Mutations in the Reactive Thiol Region† |
Q73712699 | Kinetic analyses of a truncated mammalian myosin I suggest a novel isomerization event preceding nucleotide binding |
Q44594103 | Kinetic analysis of Drosophila muscle myosin isoforms suggests a novel mode of mechanochemical coupling |
Q40792968 | Kinetic analysis of the slow skeletal myosin MHC-1 isoform from bovine masseter muscle |
Q79167129 | Kinetic and mechanistic basis of the nonprocessive Kinesin-3 motor NcKin3 |
Q36542676 | Kinetic characterization of a cytoplasmic myosin motor domain expressed in Dictyostelium discoideum. |
Q38288079 | Kinetic characterization of the catalytic domain of Dictyostelium discoideum myosin. |
Q59663138 | Kinetics of acto-S1 interaction as a guide to a model for the crossbridge cycle |
Q45114735 | Kinetics of an enzyme-catalyzed reaction measured by electrospray ionization mass spectrometry using a simple rapid mixing attachment. |
Q71715239 | Kinetics of nucleotide binding to pyruvate carboxylase |
Q45226232 | Kinetics of the interaction of 2'(3')-O-(N-methylanthraniloyl)-ATP with myosin subfragment 1 and actomyosin subfragment 1: Characterization of two acto.cntdot.S1.cntdot.ADP complexes |
Q36562803 | Looking at long molecules in solution: what happens when they are subjected to Couette flow? |
Q46568454 | Loop 1 of transducer region in mammalian class I myosin, Myo1b, modulates actin affinity, ATPase activity, and nucleotide access. |
Q74540838 | Loop I can modulate ADP affinity, ATPase activity, and motility of different scallop myosins. Transient kinetic analysis of S1 isoforms |
Q64235498 | Measurement of Myofilament-Localized Calcium Dynamics in Adult Cardiomyocytes and the Effect of Hypertrophic Cardiomyopathy Mutations |
Q70533616 | Mechanism of adenosine 5'-triphosphate cleavage by myosin: studies with oxygen-18-labeled adenosine 5'-triphosphate |
Q48019624 | Mechanism, regulation, and functional properties of Dictyostelium myosin-1B. |
Q90696298 | Mg2+ -free ATP regulates the processivity of native cytoplasmic dynein |
Q74599218 | Microsecond folding of the cold shock protein measured by a pressure-jump technique |
Q38905575 | Modeling the Actin.myosin ATPase Cross-Bridge Cycle for Skeletal and Cardiac Muscle Myosin Isoforms. |
Q28575899 | Modification of loop 1 affects the nucleotide binding properties of Myo1c, the adaptation motor in the inner ear |
Q58491145 | Modulation of Actin Affinity and Actomyosin Adenosine Triphosphatase by Charge Changes in the Myosin Motor Domain† |
Q104694412 | Modulation of post-powerstroke dynamics in myosin II by 2'-deoxy-ADP |
Q48320291 | Modulators of actin-myosin dissociation: basis for muscle type functional differences during fatigue |
Q90857341 | Molecular features of the UNC-45 chaperone critical for binding and folding muscle myosin |
Q36144111 | Molecular mechanism of actomyosin-based motility. |
Q54488142 | More Can Mean Less, or: Simplifying Sometimes Requires Ideas to Be More Complicated. |
Q121177155 | Multiscale modeling of twitch contractions in cardiac trabeculae |
Q58491097 | Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium |
Q40398998 | Mutations in the relay loop region result in dominant-negative inhibition of myosin II function in Dictyostelium |
Q24610102 | Myo1c is designed for the adaptation response in the inner ear |
Q34459239 | Myo1c mutations associated with hearing loss cause defects in the interaction with nucleotide and actin. |
Q26770575 | Myosin isoforms and the mechanochemical cross-bridge cycle |
Q90466801 | Myosin motor domains carrying mutations implicated in early or late onset hypertrophic cardiomyopathy have similar properties |
Q92858875 | Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity |
Q31854490 | Overexpression of human cardiac troponin in Escherichia coli: its purification and characterization. |
Q39234683 | Phosphorylation of Ser283 enhances the stiffness of the tropomyosin head-to-tail overlap domain |
Q38119858 | Polymorphism in tropomyosin structure and function |
Q69680088 | Pressure sensitivity of active tension in glycerinated rabbit psoas muscle fibres: effects of ADP and phosphate |
Q71586048 | Pressure-induced changes in the isometric contractions of single intact frog muscle fibres at low temperatures |
Q44657400 | Probing nucleotide dissociation from myosin in vitro using microgram quantities of myosin. |
Q42118754 | Production of amino-terminally acetylated recombinant proteins in E. coli |
Q72529664 | Protein-bound adenosine 5'-triphosphate: properties of a key intermediate of the magnesium-dependent subfragment 1 adenosinetriphosphatase from rabbit skeletal muscle |
Q48718220 | Proteins: from chemical to physiological mechanism. |
Q28236967 | Rapid folding of the prion protein captured by pressure-jump |
Q38237246 | Rapid reaction kinetic techniques. |
Q43199021 | Resolution and uniqueness of estimated parameters of a model of thin filament regulation in solution. |
Q35610635 | Reversible movement of switch 1 loop of myosin determines actin interaction |
Q38803218 | Review: The ATPase mechanism of myosin and actomyosin. |
Q54295386 | Role of the head-to-tail overlap region in smooth and skeletal muscle beta-tropomyosin. |
Q53929131 | Role of the salt-bridge between switch-1 and switch-2 of Dictyostelium myosin. |
Q80162383 | Role of tropomyosin isoforms in the calcium sensitivity of striated muscle thin filaments |
Q80195387 | Selective perturbation of the myosin recovery stroke by point mutations at the base of the lever arm affects ATP hydrolysis and phosphate release |
Q70782795 | Separation and characterization of the two functional regions of troponin involved in muscle thin filament regulation |
Q37946073 | Shaking the myosin family tree: biochemical kinetics defines four types of myosin motor |
Q121177150 | Single-molecule imaging reveals how mavacamten and PKA modulate ATP turnover in skeletal muscle myofibrils |
Q58491123 | Stabilization of the Actomyosin Complex by Negative Charges on Myosin† |
Q42540953 | Strain-dependent cross-bridge cycle for muscle. |
Q42540958 | Strain-dependent cross-bridge cycle for muscle. II. Steady-state behavior. |
Q43863354 | Stretching the lever-arm theory. |
Q27671754 | Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V |
Q33953597 | Structural mechanism of muscle contraction. |
Q28623694 | Substrate specificity of human nucleoside-diphosphate kinase revealed by transient kinetic analysis |
Q121177105 | TORC2 dependent phosphorylation modulates calcium regulation of fission yeast myosin |
Q83227757 | TORC2-Gad8-dependent myosin phosphorylation modulates regulation by calcium |
Q33784412 | Targeted amino-terminal acetylation of recombinant proteins in E. coli |
Q47406906 | Temperature manifold for a stopped-flow machine to allow measurements from -10 to +40°C. |
Q47591174 | Temperature sensitive point mutations in fission yeast tropomyosin have long range effects on the stability and function of the actin-tropomyosin copolymer |
Q69911341 | Tension responses to increased hydrostatic pressure in glycerinated rabbit psoas muscle fibres |
Q92459947 | The ATPase cycle of human muscle myosin II isoforms: Adaptation of a single mechanochemical cycle for different physiological roles |
Q35836060 | The Hill model for binding myosin S1 to regulated actin is not equivalent to the McKillop-Geeves model |
Q36876238 | The Most Prevalent Freeman-Sheldon Syndrome Mutations in the Embryonic Myosin Motor Share Functional Defects |
Q30381592 | The Relay/Converter Interface Influences Hydrolysis of ATP by Skeletal Muscle Myosin II. |
Q73578570 | The XXVIII European Muscle conference. York, UK, 4-7 September 1999 |
Q82731170 | The XXXVII European muscle conference: Oxford September 2008 |
Q35257399 | The actomyosin ATPase: a two-state system |
Q28247638 | The core FH2 domain of diaphanous-related formins is an elongated actin binding protein that inhibits polymerization |
Q69890965 | The dynamics of the interaction between myosin subfragment 1 and pyrene-labelled thin filaments, from rabbit skeletal muscle |
Q67904532 | The effect of hydrostatic pressure on the interaction of actomyosin subfragment 1 with nucleotides |
Q36143822 | The flexibility of two tropomyosin mutants, D175N and E180G, that cause hypertrophic cardiomyopathy |
Q30356929 | The hypertrophic cardiomyopathy myosin mutation R453C alters ATP binding and hydrolysis of human cardiac β-myosin |
Q72725586 | The influence of 2,3-butanedione 2-monoxime (BDM) on the interaction between actin and myosin in solution and in skinned muscle fibres |
Q71824990 | The limiting rate of the ATP-mediated dissociation of actin from rabbit skeletal muscle myosin subfragment 1 |
Q90388612 | The mechanism of thin filament regulation: Models in conflict? |
Q36288552 | The molecular mechanism of muscle contraction. |
Q38205172 | The myosin-activated thin filament regulatory state, M⁻-open: a link to hypertrophic cardiomyopathy (HCM). |
Q42101523 | The regulation of myosin binding to actin filaments by Lethocerus troponin. |
Q39656476 | The role of three-state docking of myosin S1 with actin in force generation. |
Q79386309 | The slow skeletal muscle isoform of myosin shows kinetic features common to smooth and non-muscle myosins |
Q30352527 | The superfast human extraocular myosin is kinetically distinct from the fast skeletal IIa, IIb, and IId isoforms. |
Q77797693 | The use of fast kinetic systems for the study of ng-microgram quantities of purified muscle proteins |
Q52722149 | The use of pressure perturbations to investigate the interaction of rabbit muscle myosin subfragment 1 with actin in the presence of MgADP. |
Q37457012 | Three-dimensional stochastic model of actin-myosin binding in the sarcomere lattice. |
Q46472537 | Towards a unified theory of muscle contraction. I: foundations. |
Q31050066 | Toxoplasma gondii myosin A and its light chain: a fast, single-headed, plus-end-directed motor |
Q38458847 | Tropomyosin and actin isoforms modulate the localization of tropomyosin strands on actin filaments. |
Q75366742 | Tropomyosin exon 6b is troponin-specific and required for correct acto-myosin regulation |
Q36207989 | Tuning the calcium sensitivity of cardiac muscle |
Q35150221 | Two Drosophila myosin transducer mutants with distinct cardiomyopathies have divergent ADP and actin affinities |
Q38439597 | Ultra short yeast tropomyosins show novel myosin regulation |
Q55396849 | Ultrafast glutamate sensors resolve high-frequency release at Schaffer collateral synapses. |
Q38950646 | Upregulation of cardiomyocyte ribonucleotide reductase increases intracellular 2 deoxy-ATP, contractility, and relaxation. |
Q38237248 | Use of pyrene-labelled actin to probe actin-myosin interactions: kinetic and equilibrium studies. |
Q43116209 | Using fluorescent myosin to directly visualize cooperative activation of thin filaments |
Q39316212 | What kinesin does at roadblocks: the coordination mechanism for molecular walking |
Q46833542 | What limits the velocity of fast-skeletal muscle contraction in mammals? |
Q43092360 | α-Tropomyosin with a D175N or E180G mutation in only one chain differs from tropomyosin with mutations in both chains |
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