| scholarly article | Q13442814 |
| P50 | author | H.L. Granzier | Q67484897 |
| Boban Stojanović | Q82951202 | ||
| Thomas C Irving | Q90286727 | ||
| Srboljub M Mijailovich | Q92858869 | ||
| Michael A. Geeves | Q50688013 | ||
| P2093 | author name string | Djordje Nedic | |
| Marina Svicevic | |||
| P2860 | cites work | Steric-model for activation of muscle thin filaments 1 1 Edited by P.E. Wright | Q58052724 |
| Myosin Head Configurations in Resting and Contracting Murine Skeletal Muscle | Q58760797 | ||
| Structure of co-crystals of tropomyosin and troponin | Q59071224 | ||
| Mechanically driven contour-length adjustment in rat cardiac titin's unique N2B sequence: titin is an adjustable spring. | Q64975511 | ||
| Proteolytic fragments of troponin C. Localization of high and low affinity Ca2+ binding sites and interactions with troponin I and troponin T | Q67355702 | ||
| X-ray diffraction from striated muscles and nerves in normal and dystrophic mice | Q70379574 | ||
| The calcium and magnesium binding sites on cardiac troponin and their role in the regulation of myofibrillar adenosine triphosphatase | Q70535990 | ||
| Mechanical properties of tropomyosin and implications for muscle regulation | Q71187088 | ||
| Length, force, and Ca(2+)-troponin C affinity in cardiac and slow skeletal muscle | Q72410942 | ||
| Tropomyosin length and two-stranded F-actin flexibility in the thin filament | Q72819623 | ||
| Myofilament lattice spacing as a function of sarcomere length in isolated rat myocardium | Q73112836 | ||
| Differential expression of cardiac titin isoforms and modulation of cellular stiffness | Q73333652 | ||
| Titin-based modulation of calcium sensitivity of active tension in mouse skinned cardiac myocytes | Q73932329 | ||
| Titin-based modulation of active tension and interfilament lattice spacing in skinned rat cardiac muscle | Q81355284 | ||
| The giant muscle protein titin is an adjustable molecular spring | Q83283351 | ||
| A Spatially Explicit Model Shows How Titin Stiffness Modulates Muscle Mechanics and Energetics | Q89088349 | ||
| Nebulin regulates thin filament length, contractility, and Z-disk structure in vivo | Q24299585 | ||
| Mutations in the nebulin gene associated with autosomal recessive nemaline myopathy | Q24649442 | ||
| Titin-based tension in the cardiac sarcomere: molecular origin and physiological adaptations | Q26996063 | ||
| Interactions between connected half-sarcomeres produce emergent mechanical behavior in a mathematical model of muscle | Q27335237 | ||
| The amino acid sequence of bovine cardiac tamponin-C. Comparison with rabbit skeletal troponin-C | Q28205167 | ||
| Regulation of the interaction between actin and myosin subfragment 1: evidence for three states of the thin filament | Q28255352 | ||
| Evidence that nebulin is a protein-ruler in muscle thin filaments | Q28278748 | ||
| Understanding the organisation and role of myosin binding protein C in normal striated muscle by comparison with MyBP-C knockout cardiac muscle | Q28295237 | ||
| Regulation of contraction in striated muscle | Q28610114 | ||
| Single molecule force spectroscopy on titin implicates immunoglobulin domain stability as a cardiac disease mechanism. | Q30425614 | ||
| X-ray diffraction from nonuniformly stretched helical molecules | Q30763453 | ||
| Visualization of cardiac muscle thin filaments and measurement of their lengths by electron tomography | Q30851629 | ||
| Sarcomere-length dependence of lattice volume and radial mass transfer of myosin cross-bridges in rat papillary muscle | Q31041846 | ||
| A spatially explicit nanomechanical model of the half-sarcomere: myofilament compliance affects Ca(2+)-activation | Q33210633 | ||
| A comparison of muscle thin filament models obtained from electron microscopy reconstructions and low-angle X-ray fibre diagrams from non-overlap muscle | Q33247663 | ||
| Nebulin plays a direct role in promoting strong actin-myosin interactions | Q33613267 | ||
| Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole. | Q33654696 | ||
| Myofilament length dependent activation | Q33787650 | ||
| The relationship between curvature, flexibility and persistence length in the tropomyosin coiled-coil | Q33798569 | ||
| Altered myofilament function depresses force generation in patients with nebulin-based nemaline myopathy (NEM2). | Q33798635 | ||
| Molecular model of muscle contraction | Q33855050 | ||
| Cooperative [Ca²+]-dependent regulation of the rate of myosin binding to actin: solution data and the tropomyosin chain model. | Q33922832 | ||
| The force exerted by a single kinesin molecule against a viscous load | Q34018422 | ||
| X-ray diffraction measurements of the extensibility of actin and myosin filaments in contracting muscle | Q34019085 | ||
| X-ray diffraction evidence for the extensibility of actin and myosin filaments during muscle contraction | Q34019091 | ||
| Electron microscopy and persistence length analysis of semi-rigid smooth muscle tropomyosin strands. | Q34032786 | ||
| Compliance of thin filaments in skinned fibers of rabbit skeletal muscle | Q34047209 | ||
| Passive tension in cardiac muscle: contribution of collagen, titin, microtubules, and intermediate filaments | Q34128718 | ||
| Myosin binding-induced cooperative activation of the thin filament in cardiac myocytes and skeletal muscle fibers | Q34129169 | ||
| Compliant realignment of binding sites in muscle: transient behavior and mechanical tuning. | Q34167501 | ||
| Cooperative regulation of myosin-actin interactions by a continuous flexible chain I: actin-tropomyosin systems. | Q34181116 | ||
| Cooperative regulation of myosin-actin interactions by a continuous flexible chain II: actin-tropomyosin-troponin and regulation by calcium. | Q34181121 | ||
| Proposed mechanism of force generation in striated muscle | Q34223986 | ||
| Truncations of titin causing dilated cardiomyopathy. | Q34254460 | ||
| Persistence length of human cardiac α-tropomyosin measured by single molecule direct probe microscopy. | Q34318478 | ||
| Mouse intact cardiac myocyte mechanics: cross-bridge and titin-based stress in unactivated cells. | Q34439598 | ||
| Nebulin deficiency in adult muscle causes sarcomere defects and muscle-type-dependent changes in trophicity: novel insights in nemaline myopathy | Q34482872 | ||
| HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy | Q34491330 | ||
| Nebulin, a major player in muscle health and disease | Q34592389 | ||
| Fast skeletal muscle troponin activation increases force of mouse fast skeletal muscle and ameliorates weakness due to nebulin-deficiency | Q34598238 | ||
| Cardiac titin and heart disease | Q34721100 | ||
| Titin as a modular spring: emerging mechanisms for elasticity control by titin in cardiac physiology and pathophysiology | Q35144639 | ||
| Novel mutations in NEB cause abnormal nebulin expression and markedly impaired muscle force generation in severe nemaline myopathy | Q35166263 | ||
| Genetic variation in titin in arrhythmogenic right ventricular cardiomyopathy-overlap syndromes | Q35197101 | ||
| The sarcomeric protein nebulin: another multifunctional giant in charge of muscle strength optimization | Q35778626 | ||
| The Hill model for binding myosin S1 to regulated actin is not equivalent to the McKillop-Geeves model | Q35836060 | ||
| Direct measurement of stiffness of single actin filaments with and without tropomyosin by in vitro nanomanipulation | Q36015047 | ||
| Titin extensibility in situ: entropic elasticity of permanently folded and permanently unfolded molecular segments | Q36276684 | ||
| Titin/connectin-based modulation of the Frank-Starling mechanism of the heart | Q36384578 | ||
| Titin determines the Frank-Starling relation in early diastole | Q36412370 | ||
| Comparison between the sarcomere length-force relations of intact and skinned trabeculae from rat right ventricle. Influence of calcium concentrations on these relations | Q36476237 | ||
| Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profile | Q36532856 | ||
| Titin strain contributes to the Frank-Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins | Q36646689 | ||
| Titin is a major human disease gene | Q36675841 | ||
| Refinement of the F-actin model against X-ray fiber diffraction data by the use of a directed mutation algorithm. | Q36757327 | ||
| Sarcoplasmic reticulum calcium uptake and speed of relaxation are depressed in nebulin-free skeletal muscle | Q36804918 | ||
| Role of Titin Missense Variants in Dilated Cardiomyopathy | Q36836249 | ||
| Thin filament length dysregulation contributes to muscle weakness in nemaline myopathy patients with nebulin deficiency | Q37223258 | ||
| Recessive truncating titin gene, TTN, mutations presenting as centronuclear myopathy | Q37227067 | ||
| Shortening of the elastic tandem immunoglobulin segment of titin leads to diastolic dysfunction | Q37292468 | ||
| Nebulin alters cross-bridge cycling kinetics and increases thin filament activation: a novel mechanism for increasing tension and reducing tension cost | Q37431381 | ||
| Three-dimensional stochastic model of actin-myosin binding in the sarcomere lattice. | Q37457012 | ||
| Roles of titin in the structure and elasticity of the sarcomere | Q37772087 | ||
| Single particle analysis of relaxed and activated muscle thin filaments. | Q38447830 | ||
| The calcium and magnesium binding sites on troponin and their role in the regulation of myofibrillar adenosine triphosphatase | Q39736326 | ||
| Truncation of titin's elastic PEVK region leads to cardiomyopathy with diastolic dysfunction | Q39955523 | ||
| The stiffness of skeletal muscle in isometric contraction and rigor: the fraction of myosin heads bound to actin | Q40120574 | ||
| Extensibility and symmetry of actin filaments in contracting muscles | Q40154851 | ||
| The measurement and dynamic implications of thin filament lengths in heart muscle | Q40709469 | ||
| Length-dependent activation: its effect on the length-tension relation in cat ventricular muscle | Q41051332 | ||
| Architecture and function in the muscle sarcomere | Q41420199 | ||
| Thin filament length in the cardiac sarcomere varies with sarcomere length but is independent of titin and nebulin | Q41613607 | ||
| Myosin filament activation in the heart is tuned to the mechanical task. | Q41710182 | ||
| The filament lattice of striated muscle | Q41751217 | ||
| Calcium binding to cardiac troponin C | Q41919583 | ||
| Sizes of components in frog skeletal muscle measured by methods of stereology | Q41921074 | ||
| Cooperative regulation of myosin-S1 binding to actin filaments by a continuous flexible Tm-Tn chain | Q42267863 | ||
| The role of super-relaxed myosin in skeletal and cardiac muscle | Q42278153 | ||
| Experimentally Increasing the Compliance of Titin Through RNA Binding Motif-20 (RBM20) Inhibition Improves Diastolic Function In a Mouse Model of Heart Failure With Preserved Ejection Fraction. | Q42382004 | ||
| Cooperativity and switching within the three-state model of muscle regulation. | Q42690203 | ||
| Resolution and uniqueness of estimated parameters of a model of thin filament regulation in solution. | Q43199021 | ||
| Variation of thin filament length in heart muscles | Q43460577 | ||
| The shape and flexibility of tropomyosin coiled coils: implications for actin filament assembly and regulation. | Q46383913 | ||
| Effects of cross-bridge compliance on the force-velocity relationship and muscle power output. | Q47239111 | ||
| Regulation of Contraction by the Thick Filaments in Skeletal Muscle | Q47270685 | ||
| Role of titin in cardiomyopathy: from DNA variants to patient stratification. | Q47296074 | ||
| The complete mouse nebulin gene sequence and the identification of cardiac nebulin | Q47935591 | ||
| Mutations of TTN, encoding the giant muscle filament titin, cause familial dilated cardiomyopathy | Q48324170 | ||
| Elasticity of alpha-helical coiled coils. | Q51923284 | ||
| Titin isoform variance and length dependence of activation in skinned bovine cardiac muscle. | Q52009485 | ||
| Dilated cardiomyopathy myosin mutants have reduced force-generating capacity. | Q52318721 | ||
| Congenital titinopathy: Comprehensive characterisation and pathogenic insights. | Q52565198 | ||
| The length-tension curve in muscle depends on lattice spacing. | Q52757824 | ||
| Titin and the sarcomere symmetry paradox. | Q52863260 | ||
| Nebulin increases thin filament stiffness and force per cross-bridge in slow-twitch soleus muscle fibers | Q57290201 | ||
| Nebulin stiffens the thin filament and augments cross-bridge interaction in skeletal muscle | Q57292344 | ||
| Genotype?phenotype correlations in nemaline myopathy caused by mutations in the genes for nebulin and skeletal muscle ?-actin | Q57394316 | ||
| P433 | issue | 5 | |
| P304 | page(s) | 680-704 | |
| P577 | publication date | 2019-04-04 | |
| P1433 | published in | The Journal of General Physiology | Q1092259 |
| P1476 | title | Nebulin and titin modulate cross-bridge cycling and length-dependent calcium sensitivity | |
| P478 | volume | 151 |
| Q93038990 | Elastic domains of giant proteins in striated muscle: Modeling compliance with rulers |
| Q91692798 | Estimation of Forces on Actin Filaments in Living Muscle from X-ray Diffraction Patterns and Mechanical Data |
| Q93010265 | Expressing a Z-disk nebulin fragment in nebulin-deficient mouse muscle: effects on muscle structure and function |
| Q92946914 | Nebulin: big protein with big responsibilities |
| Q93109792 | Progress on the regulation of myofibrillar function: Part 2 |
| Q90388612 | The mechanism of thin filament regulation: Models in conflict? |
| Q96126584 | Triggering typical nemaline myopathy with compound heterozygous nebulin mutations reveals myofilament structural changes as pathomechanism |
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